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dc.creatorAhumada, Edgar
dc.creatorDelgado, Daniel
dc.creatorMartínez, Fleming
dc.date.accessioned2019-07-03T17:58:30Z
dc.date.available2019-07-03T17:58:30Z
dc.date.created2012
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/74504
dc.descriptionThe Extended Hildebrand Solubility Approach(EHSA) was applied in the presentwork to evaluate the solubility of theanalgesic drug acetaminophen (paracetamol)in polyethylene glycol 400 + watermixtures at 298.15 K. An acceptablecorrelative capacity of EHSA was foundusing a regular polynomial model in orderfour (overall deviation below 0.7%),when the W interaction parameter is relatedto the solubility parameter of themixtures. Thus, the deviations obtainedin the estimated solubility with respect toexperimental solubility were lower thanthose obtained directly by means of anempiric regression of the experimentalsolubility as a function of the mixtures’solubility parameters (close to 1.5%).
dc.formatapplication/pdf
dc.publisherUniversidad Nacional de Colombia
dc.relationhttp://revistas.unal.edu.co/index.php/rcolquim/article/view/42917
dc.relation.ispartofUniversidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Química
dc.relation.ispartofRevista Colombiana de Química
dc.relation.ispartofseriesRevista Colombiana de Química; Vol. 41, núm. 3 (2012); 433-448 0120-2804
dc.subjectacetaminophen
dc.subjectbinary mixtures
dc.subjectextended Hildebrand solubility approach
dc.subjectsolubility parameter.
dc.titleSolubility of acetaminophen in polyethylene glycol 400 + water mixtures according to the extended hildebrand solubility approach
dc.typeinfo:eu-repo/semantics/article
dc.type.spaArtículo - Article
dc.type.hasversioninfo:eu-repo/semantics/publishedVersion
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.identifier.bibliographicCitationAhumada, Edgar and Delgado, Daniel and Martínez, Fleming (2012) Solubility of acetaminophen in polyethylene glycol 400 + water mixtures according to the extended hildebrand solubility approach. Revista Colombiana de Química; Vol. 41, núm. 3 (2012); 433-448 0120-2804 .
dc.identifier.eprintshttp://bdigital.unal.edu.co/38981/


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