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dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacional
dc.contributor.advisorCarrillo Bayona, Jorge Alberto
dc.contributor.advisorOrtíz Ruíz, Guillermo
dc.contributor.authorPrieto Granados, Chiesie Camila
dc.date.accessioned2021-01-15T14:28:45Z
dc.date.available2021-01-15T14:28:45Z
dc.date.issued2020-11-25
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/78754
dc.description.abstractObjetivo: estudio de corte retrospectiva para estimar la asociación del puntaje RALE con desenlaces clínicos en pacientes con diagnóstico de SDRA definido por criterios de Berlín. Metodología: Se evaluó el puntaje RALE de 73 pacientes de la Unidad de Cuidado Intensivo del Hospital Universitario Nacional de Colombia en la radiografía inicial y en un control a los 3 días, por dos radiologos, calculandose la concordacioa intra e interobservador con gráficos de dispersión de Bland-Altman y coeficiente de Lin. Se asocio el puntaje RALE con la mortalidad, la supervivencia y los días libres de ventilador usando regresión logística no condicional multivariada, método de Kaplan Meier y modelos de regresión de Cox multivariado. Finalmente, se determinó la asociación del cambio del puntaje RALE en relación a la severidad de SDRA mediante un modelo de regresión lineal multivariado. Resultados: no se encontro correlación significativa entre el Puntaje RALE con la mortalidad y la supervivencia global (OR 0.99 IC 95% 0.94 – 1.05 y HR 0.99 IC 95% 0.95 -1.04), el cambio en el SOFA, la edad y la presencia de falla renal fueron las unicas variables asociadas con la mortalidad con significancia estadistica. Además, se evidencio pobre correlación interobservador al momento de aplicar el puntaje RALE. Conclusión: la muestra de este estudio es menor a la estimada, por lo que las asociaciones evaluadas no tienen relevancia estaditicamente significativa. Además, la pobre concordacia en el puntaje RALE entre radiologos no expertos, denota subjetividad de la escala.
dc.description.abstractObjective: A retrospective cross-sectional study to estimate the association between the RALE score and clinical outcomes, in patients with diagnosis of ARDS defined by the Berlin criteria. Methods: The RALE score of 73 patients from the Intensive Care Unit of the National University Hospital of Colombia was evaluated in the initial radiography and in a follow-up at 3 days, by two radiologists, calculating the intra and interobserver concordance with Bland-Altman plot and Lin's coefficient. The RALE score was associated with mortality, survival, and ventilator-free days using multivariate unconditional logistic regression, Kaplan Meier method, and multivariate Cox regression models. Finally, the association of the change in the RALE score in relation to the severity of ARDS was determined using a multivariate linear regression model. Results: no significant correlation was found between the RALE score with mortality and overall survival (OR 0.99 CI 95% 0.94 – 1.05 y HR 0.99 CI 95% 0.95 -1.04), the change in SOFA, age and the presence of renal failure were the only variables associated with mortality with statistical significance. In addition, a poor inter-observer correlation was evidenced when the RALE score was applied by two non-expert thorax radiologists. Conclusions: the sample of this study is smaller than the estimated one, so the associations evaluated have no statistically significant relevance. Furthermore, the poor concordance in the RALE score among non-expert radiologists denotes subjectivity of the scale.
dc.format.extent77
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.rightsDerechos reservados - Universidad Nacional de Colombia
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc610 - Medicina y salud::616 - Enfermedades
dc.titleAsociación del puntaje de evaluación del Edema Pulmonar en Radiografía de tórax (RALE) con desenlaces clínicos en adultos con síndrome de dificultad respiratoria aguda hospitalizados en dos unidades de cuidado intensivo de la ciudad de Bogotá
dc.title.alternativeAssociation between Radiographic Assessment of Lung Oedema (RALE) score and clinical outcomes in adults with Acute Respiratory distress Syndrome hospitalized in two Intensive Care Units in Bogotá
dc.typeOtro
dc.rights.spaAcceso abierto
dc.type.driverinfo:eu-repo/semantics/other
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.publisher.programBogotá - Medicina - Especialidad en Radiología e Imágenes Diagnósticas
dc.contributor.colaboratorZambrano Muñoz, Fernán Santiago
dc.contributor.colaboratorAranda Hernández, Miguel Andrés
dc.contributor.colaboratorGuerra Londoño, Juan José
dc.contributor.colaboratorCelis Trujillo, Jimmy Julián
dc.contributor.colaboratorPlata Ortega, Nicolás Hernando
dc.description.degreelevelEspecialidades Médicas
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotá
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.subject.proposalAcute Respiratory Distress Syndrome
dc.subject.proposalSíndrome de dificultad respiratoria aguda
dc.subject.proposalPuntuación de evaluación radiográfica del edema pulmonar (RALE)
dc.subject.proposalRadiographic Assessment of Lung Oedema (RALE) score
dc.subject.proposalEdema pulmonar
dc.subject.proposalPulmonary edema
dc.subject.proposalFisiopatología
dc.subject.proposalRadiographic Assessment of Lung Oedema (RALE)
dc.subject.proposalEvaluación Radiográfica del Edema Pulmonar (RALE)
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Atribución-NoComercial-SinDerivadas 4.0 InternacionalThis work is licensed under a Creative Commons Reconocimiento-NoComercial 4.0.This document has been deposited by the author (s) under the following certificate of deposit