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dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacional
dc.contributor.advisorBlanco Castañeda, Liliana
dc.contributor.authorRodríguez Arango, Emiliano
dc.date.accessioned2021-02-22T20:50:18Z
dc.date.available2021-02-22T20:50:18Z
dc.date.issued2020-07-30
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/79283
dc.description.abstractIn this paper we present a study of an response-adaptive design study described in terms of a two-color ball urn model. Through simulations, possible advantages of this design were explored by modifying the values of the initialization parameters. An exploratory analysis of the number of patients assigned to the lower treatment by the design was made and the power of the hypothesis test carried out to compare the two treatments considered was explored. It was found that within the initialization parameters considered those that presented the lowest values of the calculated statistics were = 0:9 and = 0:9. As for the power of the hypothesis test, it was found that they were practically the same (values very close together) for each one of the choices of and considered, under the same diference of the means and the same sample size.
dc.description.abstractEn este trabajo se presenta un estudio de un diseño de respuesta adaptada descrito en términos de un modelo de urna de dos colores. A través de simulaciones se exploraron posibles ventajas de este diseño modi cando los valores de los parámetros de inicialización. Posteriormente se llevó a cabo un análisis exploratorio del número de pacientes asignados al tratamiento inferior por parte del diseño y se exploró la potencia de la prueba de hipótesis realizada para comparar los dos tratamientos considerados. Se encontró que, dentro de los parámetros de inicialización considerados, los que presentaron los valores más bajos de los estadísticos calculados fueron = 0:9 y = 0:9. En cuanto a la potencia de la prueba de hipótesis se encontró que eran prácticamente iguales (valores muy cercanos entre ellas) para cada una de las escogencias de y consideradas, bajo una misma diferencia de medias y un mismo tamaño de muestra.
dc.format.extent1 recurso en línea (68 páginas)
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.rightsDerechos reservados - Universidad Nacional de Colombia
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectUrn Model
dc.subjectDiseño de respuesta adaptada
dc.subjectModelo RRU
dc.subjectModelo MRRU
dc.subject.ddc510 - Matemáticas::519 - Probabilidades y matemáticas aplicadas
dc.titleModelo modificado de urna reforzada aleatoriamente (MRRU) y su aplicación en la asignación aleatoria de pacientes a tratamientos médicos
dc.typeOtro
dc.rights.spaAcceso abierto
dc.subject.keywordUrn Model
dc.subject.keywordResponse Adaptive Designs
dc.subject.keywordRRU Model
dc.description.additionalLínea de Investigación: Procesos estocásticos
dc.type.driverinfo:eu-repo/semantics/other
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.publisher.programBogotá - Ciencias - Maestría en Ciencias - Estadística
dc.publisher.programDepartamento de Estadística
dc.contributor.researchgroupProcesos Estocásticos
dc.description.degreelevelMaestría
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotá
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Atribución-NoComercial-SinDerivadas 4.0 InternacionalThis work is licensed under a Creative Commons Reconocimiento-NoComercial 4.0.This document has been deposited by the author (s) under the following certificate of deposit