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Revisión bibliográfica de conceptos morfológicos en el desarrollo de Enfermedad de Hígado Graso no Alcohólico (EHGNA) y Esteatohepatitis no Alcohólica (EHNA)

dc.rights.licenseAtribución-NoComercial 4.0 Internacional
dc.contributor.advisorArias López, Luz Amparo
dc.contributor.authorGonzález Arias, Julián Enrique
dc.date.accessioned2024-12-11T15:07:57Z
dc.date.available2024-12-11T15:07:57Z
dc.date.issued2024
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/87290
dc.descriptionilustraciones, diagramas
dc.description.abstractLa Enfermedad de Hígado Graso no Alcohólico (EHGNA), es un tipo de hepatopatía crónica que actualmente está en crecimiento e impacta la vida de pacientes con comorbilidades metabólicas como la obesidad y la Diabetes Mellitus tipo II, que con el tiempo pueden desarrollar Esteatohepatitis no Alcohólica (EHNA), en el contexto de inflamación crónica que los pone en riesgo de desarrollar cirrosis y finalmente Hepatocarcinoma. Este tipo de patologías afecta a nivel funcional al hígado, afecciones explicables por alteraciones a múltiples niveles -molecular, celular, tisular y macroscópico-. El objetivo del presente trabajo de grado es realizar una revisión bibliográfica sobre conceptos morfológicos -en cuanto a la embriología, anatomía e histología- del hígado normal y de cómo la comprensión de estos conceptos nos permite entender los cambios patológicos y fisiopatológicos que sufre el hígado en estas patologías. Se encontraron múltiples interacciones complejas en los múltiples niveles mencionados que explican lo que sucede en la enfermedad, permitiendo identificar posibles perspectivas futuras para impactar de forma positiva a los pacientes (Texto tomado de la fuente).
dc.description.abstractNon-Alcoholic Fatty Liver Disease (NAFLD) is a type of chronic liver disease that is currently growing and impacts the lives of patients with metabolic comorbidities such as obesity and Type II Diabetes Mellitus, who over time can develop Non-Alcoholic Steatohepatitis. (NASH), in the context of chronic inflammation that puts them at risk of developing cirrhosis and finally Hepatocarcinoma. This type of pathology affects the liver at a functional level, conditions that can be explained by alterations at multiple levels - molecular, cellular, tissue and macroscopic-. The objective of this tesis is to carry out a bibliographic review on morphological concepts - in terms of embryology, anatomy and histology - of the normal liver and how the understanding of these concepts allows us to understand the pathological and pathophysiological changes that the liver undergoes in these pathologies. Multiple complex interactions were found at the multiple levels mentioned, that explain what happens in the disease, allowing the identification of possible future perspectives to positively impact patients.
dc.format.extent153 páginas
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.publisherUniversidad Nacional de Colombia
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subject.ddc610 - Medicina y salud::616 - Enfermedades
dc.titleRevisión bibliográfica de conceptos morfológicos en el desarrollo de Enfermedad de Hígado Graso no Alcohólico (EHGNA) y Esteatohepatitis no Alcohólica (EHNA)
dc.typeTrabajo de grado - Maestría
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.publisher.programBogotá - Medicina - Maestría en Morfología Humana
dc.description.degreelevelMaestría
dc.description.degreenameMagíster en Morfología Humana
dc.description.researchareaTrabajo de Grado de Profundización
dc.identifier.instnameUniversidad Nacional de Colombia
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourlhttps://repositorio.unal.edu.co/
dc.publisher.facultyFacultad de Medicina
dc.publisher.placeBogotá, Colombia
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotá
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.subject.decsEnfermedad del Hígado Graso no Alcohólico
dc.subject.decsNon-alcoholic Fatty Liver Disease
dc.subject.decsCarcinoma Hepatocelular
dc.subject.decsCarcinoma, Hepatocellular
dc.subject.decsEnfermedades del Sistema Digestivo
dc.subject.decsDigestive System Diseases
dc.subject.proposalEnfermedad por Hígado Graso No Alcohólico
dc.subject.proposalEsteatohepatitis no Alcohólica
dc.subject.proposalAnatomía
dc.subject.proposalEmbriología
dc.subject.proposalHistología
dc.subject.proposalNon-alcoholic Fatty Liver Disease
dc.subject.proposalNon-alcoholic Steatohepatitis
dc.subject.proposalAnatomy
dc.subject.proposalEmbryology
dc.subject.proposalHistology
dc.title.translatedBibliographic review of morphological concepts in the development of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.contentText
dc.type.redcolhttp://purl.org/redcol/resource_type/TM
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2
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dcterms.audience.professionaldevelopmentMaestros


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