Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine
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Artículo de revista
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EspañolPublication Date
2016-05-01Metadata
Mostrar registro completoSummary
Some Schiff bases of pyrazole and 4-amino antipyrine have been synthesized. The antibacterial screening of these synthesized compounds was done in dimethyl forma-mide against four Gram positive bacteria viz. Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidids and Micrococcus luteus, and three Gram negative bacteria viz. Proteus mirabilis, Escherichia coli and Klebsiella aerogenes. It is observed that in comparison to Schiff bases of 4-amino antipyrine, pyrazole Schiff bases are better for inhibition for these selected Gram positive and Gram negative bacterial strains.Summary
Se sintetizaron algunas bases de Schiff a partir de pirazol y 4-amino antipirina. La evaluación de la actividad antibacteriana de estos compuestos en dimetil formamida se realizó frente a cuatro bacterias Gram positivas, Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidids y Micrococcus luteus, y frente a tres bacterias Gram negativas, Proteus mirabilis, Escherichia coli y Klebsiella aerogenes. Se observó mejor inhibición bacteriana frente a las diferentes cepas para las bases de Schiff basadas en pirazol comparadas con aquellas basadas en 4-amino antipirina.Keywords
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