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Solubility of acetaminophen in polyethylene glycol 400 + water mixtures according to the extended hildebrand solubility approach

dc.rights.licenseAtribución-NoComercial 4.0 Internacional
dc.contributor.authorAhumada, Edgar
dc.contributor.authorDelgado, Daniel
dc.contributor.authorMartínez, Fleming
dc.date.accessioned2019-07-03T17:58:30Z
dc.date.available2019-07-03T17:58:30Z
dc.date.issued2012
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/74504
dc.description.abstractThe Extended Hildebrand Solubility Approach(EHSA) was applied in the presentwork to evaluate the solubility of theanalgesic drug acetaminophen (paracetamol)in polyethylene glycol 400 + watermixtures at 298.15 K. An acceptablecorrelative capacity of EHSA was foundusing a regular polynomial model in orderfour (overall deviation below 0.7%),when the W interaction parameter is relatedto the solubility parameter of themixtures. Thus, the deviations obtainedin the estimated solubility with respect toexperimental solubility were lower thanthose obtained directly by means of anempiric regression of the experimentalsolubility as a function of the mixtures’solubility parameters (close to 1.5%).
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.publisherUniversidad Nacional de Colombia
dc.relationhttp://revistas.unal.edu.co/index.php/rcolquim/article/view/42917
dc.relation.ispartofUniversidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Química
dc.relation.ispartofRevista Colombiana de Química
dc.relation.ispartofseriesRevista Colombiana de Química; Vol. 41, núm. 3 (2012); 433-448 0120-2804
dc.rightsDerechos reservados - Universidad Nacional de Colombia
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.titleSolubility of acetaminophen in polyethylene glycol 400 + water mixtures according to the extended hildebrand solubility approach
dc.typeArtículo de revista
dc.type.driverinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.eprintshttp://bdigital.unal.edu.co/38981/
dc.relation.referencesAhumada, Edgar and Delgado, Daniel and Martínez, Fleming (2012) Solubility of acetaminophen in polyethylene glycol 400 + water mixtures according to the extended hildebrand solubility approach. Revista Colombiana de Química; Vol. 41, núm. 3 (2012); 433-448 0120-2804 .
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.subject.proposalacetaminophen
dc.subject.proposalbinary mixtures
dc.subject.proposalextended Hildebrand solubility approach
dc.subject.proposalsolubility parameter.
dc.type.coarhttp://purl.org/coar/resource_type/c_6501
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.contentText
dc.type.redcolhttp://purl.org/redcol/resource_type/ART
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2


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Atribución-NoComercial 4.0 InternacionalEsta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial 4.0.Este documento ha sido depositado por parte de el(los) autor(es) bajo la siguiente constancia de depósito