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dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacional
dc.contributor.advisorArteaga Díaz, Juan Manuel
dc.contributor.advisorMartínez Peñaloza, Daniela
dc.contributor.authorMejía Sandoval, Harvey Julián
dc.date.accessioned2023-01-26T19:55:01Z
dc.date.available2023-01-26T19:55:01Z
dc.date.issued2023-01-25
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/83147
dc.description.abstractPrevalencia de osteoporosis posmenopáusica de muy alto riesgo en el Hospital Universitario Nacional Introducción: La osteoporosis posmenopáusica de muy alto riesgo (OPMAR) incluye las pacientes que tienen una mayor probabilidad de tener fracturas a corto plazo. Se define como la presencia de 1 o más de: fracturas en los últimos 12 meses, durante el tratamiento, asociada a fármaco lesivo, más de una, T-score < -3, alto riesgo de caídas, FRAX de muy alta probabilidad. Hasta el momento ningún estudio ha determinado su frecuencia y caracterización. Objetivos: determinar la frecuencia de OPMAR en el HUN, caracterizar este grupo de pacientes, identificar la distribución de los factores de riesgo, complicaciones y tratamiento recibido. Metodología: estudio observacional, descriptivo de corte transversal. Se realizó búsqueda en sistema HOSVITAL de códigos CIE10 relacionados con osteoporosis (OP) durante 2020 - 2021. Se seleccionaron las pacientes con OP posmenopáusica atendidas en consulta externa de endocrinología. Se determinó frecuencia y caracterización del grupo de muy alto riesgo. Resultados: de 502 pacientes, 221 clasificaron como OPMAR (44%), con media de edad 72. Las comorbilidades más frecuentes fueron hipertensión arterial (32,2%), diabetes tipo 2 (11,8%), insuficiencia cardiaca (10,4%) e hiperparatiroidismo secundario (7,7%). Hubo antecedente de tabaquismo en 8,6%, consumo de inhibidores de bomba de protones en 19,5%, glucocorticoides en 12,2%. El 21,3% presentaron deficiencia de vitamina D, 10,8% reportaron caídas en el último año. 43,4% tuvieron fracturas, 20,3% en columna dorsal. 30,8% recibieron manejo con teriparatida, 14,5% como terapia inicial. Conclusiones: La OPMAR es una condición de elevada frecuencia. La edad avanzada y múltiples factores contribuyen a su aparición. El principal sitio afectado fue columna dorsal. Existe un bajo uso de terapia anabólica, la cual debe preferirse en estos casos. (Texto tomado de l a fuente)
dc.description.abstractPrevalence of very high risk postmenopausal osteoporosis in the national university hospital Introduction: Very high-risk postmenopausal osteoporosis (OPMAR) includes patients who have a higher probability of having fractures in the short term. It is defined as the presence of 1 or more of: fractures in the last 12 months, during treatment, associated with an injurious drug, more than one, T-score < -3, high risk of falls, FRAX with a very high probability. To date, no study has determined its frequency and characterization. Objectives: to determine the frequency of OPMAR in the HUN, to characterize this group of patients, to identify the distribution of risk factors, complications and treatment received. Methodology: observational, descriptive cross-sectional study. A search was made in the HOSVITAL system for ICD10 codes related to osteoporosis (OP) during 2020 - 2021. Patients with postmenopausal OP seen in an endocrinology outpatient clinic were selected. Frequency and characterization of the very high risk group was determined. Results: Of 502 patients, 221 were classified as OPMAR (44%), with a mean age of 72. The most frequent comorbidities were arterial hypertension (32.2%), type 2 diabetes (11.8%), heart failure (10, 4%) and secondary hyperparathyroidism (7.7%). There was a history of smoking in 8.6%, consumption of proton pump inhibitors in 19.5%, glucocorticoids in 12.2%. 21.3% presented vitamin D deficiency, 10.8% reported falls in the last year. 43.4% had fractures, 20.3% in the thoracic column. 30.8% received management with teriparatide, 14.5% as initial therapy. Conclusions: OPMAR is a condition of high frequency. Advanced age and multiple factors contribute to its appearance. The main affected site was the dorsal column. There is a low use of anabolic therapy, which should be preferred in these cases
dc.format.extent75 páginas
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.publisherUniversidad Nacional de Colombia
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc610 - Medicina y salud
dc.titlePrevalencia de osteoporosis posmenopáusica de muy alto riesgo en el Hospital Universitario Nacional
dc.typeTrabajo de grado - Especialidad Médica
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.publisher.programBogotá - Medicina - Especialidad en Endocrinología
dc.description.degreelevelEspecialidades Médicas
dc.description.degreenameEspecialista en Endocrinología
dc.description.methodsDiseño del estudio Estudio observacional descriptivo de corte transversal. Marco muestral Población a estudio: Pacientes con diagnóstico de osteoporosis atendidas en el HUN, en el servicio de consulta externa de endocrinología, registradas en el sistema HOSVITAL. Población blanco: Pacientes con diagnóstico de osteoporosis atendidas en el HUN, durante los años 2020 a 2021, en el servicio de consulta externa de endocrinología y registradas en el sistema HOSVITAL. Se obtendrá este dato a partir de la revisión de todos los diagnósticos CIE10 registrados, relacionados con osteoporosis (M800, M801, M802, M803, M804, M805, M808, M809, M810, M811, M812, M813, M814, M815, M816, M818, M819, M820, M821, M828) en el sistema HOSVITAL, durante los años 2020 a 2021. De este grupo se seleccionarán, a través de la revisión de historias clínicas las pacientes con OPMAR, se determinará la frecuencia y se realizará su caracterización. Tipo de muestreo: Se realizará un muestreo por conveniencia donde se seleccionarán solo los pacientes con diagnóstico de osteoporosis registrados en el sistema HOSVITAL, durante los años 2020 a 2021, atendidos en el HUN.
dc.description.researchareaEndocrinología
dc.identifier.instnameUniversidad Nacional de Colombia
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourlhttps://repositorio.unal.edu.co/
dc.publisher.facultyFacultad de Medicina
dc.publisher.placeBogotá, Colombia
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotá
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.subject.lembOsteoporosis
dc.subject.lembEnfermedad de los huesos
dc.subject.lembBones - diseases
dc.subject.proposalosteoporosis posmenopáusica
dc.subject.proposalFactores de riesgo
dc.subject.proposalMuy alto riesgo
dc.subject.proposalFracturas vertebrales
dc.subject.proposalAgentes anabólicos
dc.subject.proposalPostmenopausal osteoporosis
dc.subject.proposalRisk factors
dc.subject.proposalVery high risk
dc.subject.proposalVertebral fractures
dc.subject.proposalAnabolic agents
dc.title.translatedPrevalence of very high risk postmenopausal osteoporosis in the National University Hospital
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.contentText
dc.type.redcolhttp://purl.org/redcol/resource_type/TM
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2
oaire.awardtitlePrevalencia de osteoporosis posmenopáusica de muy alto riesgo en el Hospital Universitario Nacional
dcterms.audience.professionaldevelopmentEstudiantes
dcterms.audience.professionaldevelopmentInvestigadores
dcterms.audience.professionaldevelopmentMaestros
dcterms.audience.professionaldevelopmentPúblico general
dc.contributor.orcidMejia, Harvey [0000000176595379]


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Atribución-NoComercial-SinDerivadas 4.0 InternacionalEsta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial 4.0.Este documento ha sido depositado por parte de el(los) autor(es) bajo la siguiente constancia de depósito