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Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
dc.rights.license | Atribución-NoComercial-SinDerivadas 4.0 Internacional |
dc.contributor.advisor | Rodríguez Niño, Gerardo |
dc.contributor.author | Flórez Bautista, Bayron Germán |
dc.date.accessioned | 2024-07-03T00:03:36Z |
dc.date.available | 2024-07-03T00:03:36Z |
dc.date.issued | 2024 |
dc.identifier.uri | https://repositorio.unal.edu.co/handle/unal/86364 |
dc.description | ilustraciones (principalmente a color), diagramas, mapas |
dc.description.abstract | El aceite de cannabis debido a la presencia de cannabinoides, terpenoides y flavonoides presenta funciones activas y de valor nutricional o en tratamientos para la epilepsia, manejo del dolor, inflamación y desordenes neurodegenerativos. Debido a la variedad de las propiedades físicas de sus compuestos, esta puede presentar diferentes retos a la hora de su integración como ingrediente activo en productos. Entre estos se relacionan impactos de en el perfil olfativo, impacto en la estabilizas del producto y modificaciones o pérdida de metabolitos deseados. A modo de presentar un abordaje para enfrentar estos retos, se propone la encapsulación del aceite como una metodología que permite cubrir estos frentes. Para este abordaje, se hace un primer acercamiento alrededor de la contextualización de la planta de cannabis, sus compuestos, mercado actual de su extracto y su uso en diferentes productos en el mercado reciente. Posteriormente se aborda los mecanismos de encapsulación, sus principios y el desarrollo de tres diferentes rutas para su obtención. Realizado este contexto, se selecciona la coalescencia como mecanismo de encapsulamiento debido principalmente a su acceso tecnológico y de insumos. Así mismo, debido a la falta de bibliografía de la encapsulación del aceite bajo esta metodología y materiales encapsulantes, se diseña el proceso por medio de la revisión bibliográfica de este en otras aplicaciones. A partir de esto, se obtienen partículas de un tamaño medio de 9,43μm que posteriormente son caracterizadas por medio de la medición de su potencial Z en diferentes medios de pH, análisis termogravimétrico y la presentación de su morfología por medio de microscopia electrónica de barrido. A través de estos análisis se pudo identificar la encapsulación del aceite, así como la estabilidad de estas en un medio dado para la aplicación cosmética planteada. En torno a su aplicación cosmética, se evalúo el impacto a tres diferentes concentraciones (0.15%, 0.20% y 0,25%) dentro de la formulación emulsionada cosmética. Esta estabilidad se desarrolla sometiendo al producto en un ambiente de 45°C en horno y corroborando por medio cualitativo tras su centrifugación la no separación de fases a lo largo del mes de evaluación. Finalmente, se encontró la metodología capaz de formar partículas que proveen la protección y asilamiento del aceite, igualmente, que cargas superficiales pueden favorecer la estabilidad de los sistemas emulsionados (Texto tomado de la fuente). |
dc.description.abstract | Cannabis oil, due to the presence of cannabinoids, terpenoids and flavonoids, has active functions and nutritional value or in treatments for epilepsy, pain management, inflammation, and neurodegenerative disorders. Due to the variety of physical properties of its compounds, it can present different challenges related with its integration as an active ingredient in products. These include impacts on the olfactory profile, impact on the stability of the product and modifications or loss of desired metabolites. To present an approach to face these challenges, oil encapsulation is proposed as a methodology that allows these fronts to be covered. For this approach, at first, it has made the contextualization of the cannabis plant, its compounds, current market for its extract and its use in different products in the recent market. Subsequently, the encapsulation mechanisms, their principles, and the development of three different routes to obtain them. Once this context is realized, coalescence is selected as an encapsulation mechanism mainly due to its technological and input access. Likewise, due to the lack of bibliography on oil encapsulation under this methodology and encapsulating materials, the process is designed through a bibliographic review of it in other applications. From this, particles with an average size of 9.43 μm are obtained, which are subsequently characterized by measuring their Z potential in different pH media, thermogravimetric analysis, and the presentation of their morphology by scanning electron microscopy. Through these analyzes it was possible to identify the encapsulation of the oil, as well as its stability in a specific medium for the proposed cosmetic application. Regarding its cosmetic application, the impact was evaluated at three different concentrations (0.15%, 0.20% and 0.25%) within the cosmetic emulsified formulation. This stability is developed by subjecting the product to an environment of 45°C in an oven and corroborating by qualitative means after centrifugation the non-separation of phases throughout the month of evaluation. Finally, the methodology was found capable of forming particles that provide protection and isolation of the oil, likewise, that surface charges can favor the stability of the emulsified systems (Texto tomado de la fuente). |
dc.format.extent | xx, 105 páginas |
dc.format.mimetype | application/pdf |
dc.language.iso | spa |
dc.publisher | Universidad Nacional de Colombia |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.subject.ddc | 540 - Química y ciencias afines::542 - Técnicas, procedimientos, aparatos, equipos, materiales |
dc.subject.ddc | 660 - Ingeniería química::668 - Tecnología de otros productos orgánicos |
dc.title | Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético |
dc.type | Trabajo de grado - Maestría |
dc.type.driver | info:eu-repo/semantics/masterThesis |
dc.type.version | info:eu-repo/semantics/publishedVersion |
dc.publisher.program | Bogotá - Ingeniería - Maestría en Ingeniería - Ingeniería Química |
dc.contributor.researchgroup | Grupo de Investigación en Procesos Químicos y Bioquímicos |
dc.description.degreelevel | Maestría |
dc.description.degreename | Magíster en Ingeniería - Ingeniería Química |
dc.description.researcharea | Diseño de Producto |
dc.identifier.instname | Universidad Nacional de Colombia |
dc.identifier.reponame | Repositorio Institucional Universidad Nacional de Colombia |
dc.identifier.repourl | https://repositorio.unal.edu.co/ |
dc.publisher.faculty | Facultad de Ingeniería |
dc.publisher.place | Bogotá, Colombia |
dc.publisher.branch | Universidad Nacional de Colombia - Sede Bogotá |
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dc.rights.accessrights | info:eu-repo/semantics/openAccess |
dc.subject.lemb | Cosmética |
dc.subject.lemb | Beauty culture |
dc.subject.lemb | Cosmeticos |
dc.subject.lemb | Cosmetics |
dc.subject.proposal | Microencapsulación |
dc.subject.proposal | Aceite de cannabis |
dc.subject.proposal | Coalescencia |
dc.subject.proposal | Potencial Z |
dc.subject.proposal | Emulsión |
dc.subject.proposal | Cosméticos |
dc.subject.proposal | Microencapsulation |
dc.subject.proposal | Cannabis oil |
dc.subject.proposal | Coalescence |
dc.subject.proposal | Z Potential |
dc.subject.proposal | Emulsion |
dc.subject.proposal | Cosmetics |
dc.title.translated | Encapsulation of cannabis oil for use as an active ingredient in cosmetic consumer products |
dc.type.coar | http://purl.org/coar/resource_type/c_bdcc |
dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.content | Text |
dc.type.redcol | http://purl.org/redcol/resource_type/TM |
oaire.accessrights | http://purl.org/coar/access_right/c_abf2 |
dcterms.audience.professionaldevelopment | Bibliotecarios |
dcterms.audience.professionaldevelopment | Estudiantes |
dcterms.audience.professionaldevelopment | Investigadores |
dcterms.audience.professionaldevelopment | Maestros |
dcterms.audience.professionaldevelopment | Público general |
dc.description.curriculararea | Ingeniería Química y Ambiental.Sede Bogotá |
dc.subject.umls | Aceite de cannabis |
dc.subject.umls | Cannabis oil |
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