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Passiflora ligularis Juss. (granadilla): estudios químicos y farmacológicos de una planta con potencial terapéutico

dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacional
dc.contributor.authorOspina Giraldo, Luis Fernando
dc.contributor.authorCastellanos Hernández, Leonardo
dc.contributor.authorRamos Rodríguez, Freddy Alejandro
dc.contributor.authorModesti Costa, Geison
dc.contributor.authorMena Barreto Silva, Fátima Reina
dc.contributor.authorLópez Vallejo, Fabián
dc.contributor.authorMonzón Daza, Gabriel
dc.contributor.authorMeneses Macías, Carolina
dc.contributor.authorRey Padilla, Diana Patricia
dc.contributor.authorCardona Paredes, María Isabel
dc.contributor.authorEcheverry González, Sandra Milena
dc.contributor.authorSepúlveda, Paula Michelle
dc.contributor.authorGómez Devia, Laura
dc.contributor.editorAragón Novoa, Diana Marcela
dc.date.accessioned2022-09-15T04:42:53Z
dc.date.available2022-09-15T04:42:53Z
dc.date.issued2021-08
dc.identifier.isbn9789587946420
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/82289
dc.descriptionilustraciones
dc.description.abstractEl presente libro es fruto de la investigación interdis- ciplinaria entorno a las hojas de Passiflora ligularis (granadilla) con fines medicinales, entre los grupos de investigación Principios Bioactivos de Plantas Medicinales del Departamento de Farmacia de la Universidad Nacional de Colombia, Estudio y Aprovechamiento de Productos Naturales Marinos y Frutas de Colombia del Departamento de Química de la Universidad Nacional de Colombia y el Grupo de Investigación en Fitoquímica de la Pontificia Universidad Javeriana, con apoyo del Ministerio de Ciencia, Tecnología e Innovación de Colombia. A lo largo de estas páginas, se resumen algunos de los resultados y avances más destacados de estos grupos de investigación en cuanto a la caracterización química de las hojas de esta especie dando énfasis a los flavonoides y saponinas, al estudio in silico, in vitro e in vivo de su actividad farmacológica, principalmente como hipoglicemiante y antinflamatorio, al desarrollo de metodologías analíticas precisas, exactas y reproducibles que permitan la completa caracterización del extracto optimizado obtenido como un ingrediente activo promisorio para el desarrollo de productos fitoterapéuticos, etapa actualmente en progreso. Se pretende que esta publicación permita la divulgación técnica y científica de los resultados de varios años de estudio con el fin de dar valor agregado a los cultivos de Passiflora ligularis, una planta de gran interés comercial debido a sus frutos y cuyas hojas en la actualidad son simplemente un subproducto de su cosecha, desconociendo el potencial terapéutico de las mismas y la posibilidad de convertirse en un materia prima para la obtención de productos fitoterapéuticos estables, seguros y eficaces. (texto tomado de la fuente)
dc.description.tableofcontentsPresentación -- Capítulo 1. Estudio in silico y evaluación in vitro de la actividad inhibitoria de flavonoides y saponinas identificados en hojas de Passiflora ligularis Juss. sobre las enzimas α-amilasa y α-glucosidasa -- Capítulo 2. Evaluación de la actividad antiinflamatoria del extracto acuoso, la fracción butanólica y compuestos identificados en las hojas de Passiflora ligularis Juss. -- Capítulo 3. Efecto del extracto acuoso de hojas de Passiflora ligularis Juss. y de sus metabolitos mayoritarios sobre la homeostasis de glucosa -- Capítulo 4. Metodologías analíticas para el estudio y cuantificación de flavonoides en extractos de hojas de Passiflora ligularis Juss. -- Capítulo 5. Estandarización del extracto de hojas de Passiflora ligularis Juss. (granadilla)
dc.format.extent150 páginas
dc.format.mimetypeapplication/pdf
dc.language.isospa
dc.publisherUniversidad Nacional de Colombia. Facultad de Ciencias. Departamento de Farmacia
dc.rightsUniversidad Nacional de Colombia, 2021
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc580 - Plantas::581 - Temas específicos en historia natural de las plantas
dc.titlePassiflora ligularis Juss. (granadilla): estudios químicos y farmacológicos de una planta con potencial terapéutico
dc.typeLibro
dc.type.driverinfo:eu-repo/semantics/book
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.coverage.countryColombia
dc.description.editionPrimera edición
dc.identifier.instnameUniversidad Nacional de Colombia
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourlhttps://repositorio.unal.edu.co/
dc.publisher.departmentSede Bogotá
dc.publisher.placeBogotá
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.subject.lembPlantas medicinales
dc.subject.lembBotánica médica
dc.subject.lembAnálisis químico de las plantas
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dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
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