Evaluación del potencial de la bioprospección de recursos naturales para el descubrimiento de nuevos agentes terapéuticos en salud pública
dc.contributor.advisor | Henao Riveros, Sandra Consuelo | |
dc.contributor.author | Rodriguez Pava, Cristian Nicolas | |
dc.date.accessioned | 2025-04-07T16:29:06Z | |
dc.date.available | 2025-04-07T16:29:06Z | |
dc.date.issued | 2025-03-07 | |
dc.description | ilustraciones, ilustraciones, tablas | spa |
dc.description.abstract | Las crecientes amenazas a la salud pública, como enfermedades crónicas, infecciones resistentes y la escasez de nuevos tratamientos, destacan la urgencia de soluciones innovadoras. En este contexto, Colombia, como uno de los países más biodiversos del mundo, ofrece un enorme potencial para la Bioprospección, definida como la exploración sistemática de la biodiversidad en busca de compuestos bioactivos con aplicaciones terapéuticas. Este campo abarca dimensiones económicas, sociales, éticas y políticas, reguladas por normativas como el Convenio sobre la Diversidad Biológica y el Protocolo de Nagoya. La Bioprospección en Colombia puede impulsar el desarrollo de terapias novedosas y el crecimiento económico, siempre que se respeten principios de equidad en el reparto de beneficios y se priorice la conservación de la biodiversidad. Este estudio evaluó el potencial de la Bioprospección de recursos naturales como estrategia para descubrir nuevos agentes terapéuticos en salud pública. Mediante una revisión bibliográfica y un análisis cualitativo con herramientas de codificación, se examinaron estudios relevantes, comparando Bioprospección terrestre y marina, y revisando marcos normativos globales y locales. Los resultados identificaron compuestos prometedores antimicrobianos, antiinflamatorios y anticancerígenos con casos exitosos en la Amazonía y ecosistemas marinos. Se concluye que la Bioprospección es una oportunidad clave para nuevos tratamientos, aunque enfrenta retos como la falta de financiación y la implementación efectiva de regulaciones. Se recomienda un enfoque sostenible y equitativo que integre a las comunidades y proteja la biodiversidad, posicionando a Colombia como líder si se fortalecen la normativa y la colaboración entre actores (Texto tomado de la fuente) | spa |
dc.description.abstract | The escalating threats to public health, including chronic diseases, resistant infections, and the scarcity of new treatments, underscore the urgent need for innovative solutions. In this context, Colombia, one of the world’s most biodiverse countries, holds immense potential for bioprospecting defined as the systematic exploration of biodiversity to identify bioactive compounds with therapeutic applications. This field encompasses economic, social, ethical, and political dimensions, governed by frameworks such as the Convention on Biological Diversity and the Nagoya Protocol. Bioprospecting in Colombia can drive the development of novel therapies and economic growth, provided equitable benefit-sharing and biodiversity conservation are prioritized. This study assessed the potential of bioprospecting natural resources as a strategy for discovering new therapeutic agents in public health. Through a literature review and qualitative analysis using coding tools, relevant studies were examined, comparing terrestrial and marine bioprospecting and reviewing global and local regulations. Results identified promising compounds antimicrobial, anti-inflammatory, and anticáncer with successful cases from the Amazon and marine ecosystems. The findings highlight bioprospecting as a key opportunity for new treatments, though it faces challenges like insufficient funding and regulatory implementation. A sustainable, equitable approach that integrates communities and safeguards biodiversity is recommended, positioning Colombia as a leader if regulations and stakeholder collaboration are strengthened. | eng |
dc.description.degreelevel | Maestría | spa |
dc.description.degreename | Magíster en Salud Pública | spa |
dc.format.extent | 112 páginas | spa |
dc.format.mimetype | application/pdf | spa |
dc.identifier.instname | Universidad Nacional de Colombia | spa |
dc.identifier.reponame | Repositorio Institucional Universidad Nacional de Colombia | spa |
dc.identifier.repourl | https://repositorio.unal.edu.co/ | spa |
dc.identifier.uri | https://repositorio.unal.edu.co/handle/unal/87867 | |
dc.language.iso | spa | spa |
dc.publisher | Universidad Nacional de Colombia | spa |
dc.publisher.branch | Universidad Nacional de Colombia - Sede Bogotá | spa |
dc.publisher.faculty | Facultad de Medicina | spa |
dc.publisher.place | Bogotá, Colombia | spa |
dc.publisher.program | Bogotá - Medicina - Maestría en Salud Pública | spa |
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dc.relation.references | Van Boeckel, T. P., et al. (2019). Global trends in antimicrobial use in food animals. Proceedings of the National Academy of Sciences, 116(22), 11507-11513. | spa |
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dc.relation.references | World Health Organization. (2015). Plan de acción global sobre la resistencia a los antimicrobianos. | spa |
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dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.license | Atribución-NoComercial 4.0 Internacional | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | spa |
dc.subject.ddc | 610 - Medicina y salud::613 - Salud y seguridad personal | spa |
dc.subject.decs | Biodiversidad | spa |
dc.subject.decs | Biodiversity | eng |
dc.subject.decs | Legislación como Asunto | spa |
dc.subject.decs | Legislation as Topic | eng |
dc.subject.decs | Investigación Biomédica | spa |
dc.subject.decs | Biomedical Research | eng |
dc.subject.decs | Antiinflamatorios | spa |
dc.subject.decs | Anti-Inflammatory Agents | eng |
dc.subject.proposal | Bioprospección | spa |
dc.subject.proposal | Salud pública | spa |
dc.subject.proposal | Agentes terapeuticos | spa |
dc.subject.proposal | Biodiversidad | spa |
dc.subject.proposal | Resistencia antimicrobiana | spa |
dc.subject.proposal | Desarrollo económico | spa |
dc.subject.proposal | Conservación | spa |
dc.subject.proposal | Bioprospecting | eng |
dc.subject.proposal | Biodiversity | eng |
dc.subject.proposal | Bioactive compounds | eng |
dc.subject.proposal | Public health | eng |
dc.subject.proposal | Antimicrobial resistance | eng |
dc.subject.proposal | Economic development | eng |
dc.subject.proposal | Conservation | eng |
dc.subject.proposal | Compuestos bioactivos | spa |
dc.title | Evaluación del potencial de la bioprospección de recursos naturales para el descubrimiento de nuevos agentes terapéuticos en salud pública | spa |
dc.title.translated | Evaluation of the potential of natural resource bioprospecting for the discovery of novel therapeutic agents in public health | eng |
dc.type | Trabajo de grado - Maestría | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_bdcc | spa |
dc.type.coarversion | http://purl.org/coar/version/c_ab4af688f83e57aa | spa |
dc.type.content | Text | spa |
dc.type.driver | info:eu-repo/semantics/masterThesis | spa |
dc.type.redcol | http://purl.org/redcol/resource_type/TM | spa |
dc.type.version | info:eu-repo/semantics/acceptedVersion | spa |
dcterms.audience.professionaldevelopment | Público general | spa |
oaire.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
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