MRI- γ Detector Hybrid System
| dc.contributor.advisor | Luis, Agulles Pedrós | spa |
| dc.contributor.advisor | Lopéz, Jairo Alexis | spa |
| dc.contributor.author | Abril Fajardo, Andrea Johana | spa |
| dc.date.accessioned | 2020-09-09T14:45:45Z | spa |
| dc.date.available | 2020-09-09T14:45:45Z | spa |
| dc.date.issued | 2017-12-20 | spa |
| dc.description.abstract | The medical imaging field can be divided in 2 imaging modalities: those generating the imaging information from outside the body (basically all x-ray combinations) and ones sending the image information from inside the body (nuclear medicine, US and MRI). The advantage of the latest is that they are able to give functional information (better contrast), however they lack of image resolution compared with CT, for example. The combination of resolution and functional information can be found in hybrid equipment like PET/CT, widely extended commercially. Recent advances in MRI have achieved spatial resolution close those possible with CT, while maintaining superior contrast and functional information. This has promoted its use as hybrid technique, like PET/MR or SPECT/MR. The handicap of these equipment is the influence of the magnetic field, on the γ detection system, whose solution implies high cost and sophisticated electronics . In the current study, we propose the use of MR implementing a dosimetric gel to obtain the functional image. Then it is possible to adapt the γ detector to any clinical MRI. As a result, a low cost and versatil hybrid MRI-γ detector is presented. | spa |
| dc.description.abstract | El campo de la imagen médica se puede dividir en 2 modalidades: las que generan información desde fuera del cuerpo (básicamente todas las combinaciones de rayos x) y los que envían la información de la imagen desde interior del cuerpo (medicina nuclear, US, PET y la RM). La ventaja de las últimas es que tienen la capacidad de ofrecer información funcional (mejor contraste), sin embargo; carecen de buena resolución de imagen en comparación con la CT, por ejemplo. La combinación de resolución e información funcional se puede encontrar en equipos híbridos como la PET/CT, ampliamente comercializado. Recientemente, el gran avance en RM ha sido lograr una resolución espacial cercana a la del CT, manteniendo el mejor contraste y la información funcional. Esto ha promovido su uso en equipos híbridos como la PET/MR o SPECT/MR. El mayor inconveniente de estos es la influencia del campo magnético en el sistema de detección γ , cuya solución implica altos costos y una electrónica sofisticada. En el presente estudio, se propone utilizar RM adaptando el uso de gel dosimétrico para la obtención de la imagen funcional. De esta manera es posible adaptar cada componente a un equipo de RM clínico como una alternativa versátil y de bajo costo para la obtención de imágenes con información anatómica y funcional. | spa |
| dc.description.degreelevel | Doctorado | spa |
| dc.description.project | Design and development of a low field MRI prototype for nuclear medicine | spa |
| dc.description.sponsorship | COLCIENCIAS | spa |
| dc.format.extent | 109 | spa |
| dc.format.mimetype | application/pdf | spa |
| dc.identifier.uri | https://repositorio.unal.edu.co/handle/unal/78427 | |
| dc.language.iso | eng | spa |
| dc.publisher.branch | Universidad Nacional de Colombia - Sede Bogotá | spa |
| dc.publisher.department | Departamento de Física | spa |
| dc.publisher.program | Bogotá - Ciencias - Doctorado en Ciencias - Física | spa |
| dc.relation | One dimensional spatial resolution optimization on a hybrid low field MRI-gamma detector | spa |
| dc.relation | 2D dose distribution images of a hybrid low field MRI-γ detector | spa |
| dc.relation | ACONDICIONAMIENTO DEL CAMPO MAGNETICO ́ ULTRA BAJO EN UN EQUIPO DE IRM PARA USO H ́IBRIDO EN MEDICINA NUCLEAR | spa |
| dc.relation.references | NIST photon cross section data base. \url{https://www.nist.gov/pml/xcom-photon-cross-sections-database. Accessed: 2017-11-22. | spa |
| dc.relation.references | {Agostinelli2003 S.~Agostinelli, J.~Allison, K.~Amako, J.~Apostolakis, H.~Araujo, and et.~al Arce. GEANT4 - A simulation toolkit. \em Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 506(3):250--303, 2003. | spa |
| dc.relation.references | Back Sven A~J Back. \em {Implementation of MRI gel dosimetry in radiation therapy. 1998. | spa |
| dc.relation.references | Baldock2011 C~Baldock, Y~De Deene, S~Doran, G~Ibbott, A~Jirasek, M~Lepage, M~Oldham, and L~J Schreiner. Topical Review: Polymer gel dosimetry. \em Physics in Medicine and Biology, 55(5):1--87, 2011. | spa |
| dc.relation.references | Beyer2012 T.~Beyer, L.~S. Freundenberg, J.~Czernin, and D.~W. Townsend. Erratum to: The future of hybrid imaging-part 3: Pet/mr, small-animal imaging and beyond (Insights Imaging, 10.1007/s13244-011-0085-4). \em Insights into Imaging, 3(2):189, 2012. | spa |
| dc.relation.references | Beyer2011 Thomas Beyer, Lutz~S. Freudenberg, David~W. Townsend, and Johannes Czernin. The future of hybrid imaging—part 1: hybrid imaging technologies and SPECT/CT. \em Insights into Imaging, 2(2):161--169, 2011. | spa |
| dc.relation.references | Beyer2011ct Thomas Beyer, David~W. Townsend, Johannes Czernin, and Lutz~S. Freudenberg. The future of hybrid imaging—part 2: PET/CT. \em Insights into Imaging, 2(3):225--234, 2011. | spa |
| dc.relation.references | PhysRev.73.679 N.~Bloembergen, E.~M. Purcell, and R.~V. Pound. Relaxation effects in nuclear magnetic resonance absorption. \em Phys. Rev., 73:679--712, Apr 1948. | spa |
| dc.relation.references | Bourbia2016 Nadjla Bourbia and Karim Mansour. Use of magic gel for diagnostic nuclear medicine dosimetry. \em Acta Physica Polonica B, 47(2):315--321, 2016. | spa |
| dc.relation.references | Kelly Braun, Dale Bailey, Brendan Hill, and Clive Baldock. Preliminary investigation of PAGAT polymer gel radionuclide dosimetry of Tc-99m. \em Journal of Physics: Conference Series, 164:012050, 2009. | spa |
| dc.relation.references | Cardinal Health. FDA-approved radiopharmaceuticals. pages 1--6, 2014. | spa |
| dc.relation.references | Diego Cecchin, Davide Poggiali, Lucia Riccardi, Paolo Turco, Franco Bui, and Stefano {De Marchi. Analytical and experimental FWHM of a gamma camera: theoretical and practical issues. \em PeerJ, 3:e722, 2015. | spa |
| dc.relation.references | Simon~R Cherry. Physics in Nuclear Medicine. Elsevier Health Sciences, 2012. | spa |
| dc.relation.references | Paulo~Roberto Costa, Elisabeth~Mateus Yoshimura, Denise~Yanikian Nersissian, and Camila~Souza Melo. Correlation between effective dose and radiological risk: general concepts. Radiologia Brasileira, 49(3):176--181, 2016. | spa |
| dc.relation.references | jour STEIN~GABRIEL DAY M.~J. Chemical effects of ionizing radiation in some gels. \em Nature, 1950. | spa |
| dc.relation.references | De Deene. Gel dosimetry for the dose verification of intensity modulated radiotherapy treatments. \Zeitschrift fur Medizinische Physik, 12(2):77--88, 2002. | spa |
| dc.relation.references | Yves De Deene. Review of quantitative MRI principles for gel dosimetry. \em Journal of Physics: Conference Series, 164(1):12033, 2009. | spa |
| dc.relation.references | Y~De Deene. Essential characteristics of polymer gel dosimeters. \em Journal of Physics: Conference Series, 3:34--57, 2004. | spa |
| dc.relation.references | Y~De Deene. Essential characteristics of polymer gel dosimeters. \em Journal of Physics: Conference Series, 3:34--57, 2004. | spa |
| dc.relation.references | Roger Eckhardt. Stan Ulam, John von Neumann, and the Monte Carlo Method. \em Los Alamos Science, Special Is:131--141, 1987. | spa |
| dc.relation.references | Frederic~H Fahey, Alison~B Goodkind, Donika Plyku, Kitiwat Khamwan, Shannon~E O'Reilly, Xinhua Cao, Eric~C Frey, Ye~Li, Wesley~E Bolch, George Sgouros, and S~Ted Treves. Dose Estimation in Pediatric Nuclear Medicine. \em Seminars in Nuclear Medicine, 47(2):118--125, 2017. | spa |
| dc.relation.references | Juliana~Polezze Fernandes, Bruno~Fraccini Pastorello, Draulio~Barros de~Araujo, and Oswaldo Baffa. Formaldehyde increases MAGIC gel dosimeter melting point and sensitivity. \em Physics in Medicine and Biology, 53(4):N53--N58, 2008. | spa |
| dc.relation.references | J.~S. Fleming and D.~E. Simpson. A technique for simulation of the point spread function of a gamma camera. \em Physics in Medicine and Biology, 39(9):1457--1473, 1994. | spa |
| dc.relation.references | P~M Fong, D~C Keil, M~D Does, and J~C Gore. Polymer gels for magnetic resonance imaging of radiation dose distributions at normal room atmosphere. \em Physics in medicine and biology, 46:3105--3113, 2001. | spa |
| dc.relation.references | J~I Gear, G~D Flux, E~Charles-Edwards, M~Partridge, G~Cook, and R~J Ott. The application of polymer gel dosimeters to dosimetry for targeted radionuclide therapy. \em Physics in Medicine \& Biology, 51(14):3503, 2006. | spa |
| dc.relation.references | H\'aKon Gudbjartsson and Samuel Patz. The rician distribution of noisy mri data. \em Magnetic Resonance in Medicine, 34(6):910--914, 1995. | spa |
| dc.relation.references | Haacke, E.M. Brown, R.W, Y.C.N. Cheng, M.R. Thompson, and R.~Venkatesan. \em Magnetic Resonance Imaging: Physical Principles and Sequence Design. Wiley, 2014. | spa |
| dc.relation.references | E.~L. Hahn. Spin echoes. \em Phys. Rev., 80:580--594, Nov 1950. | spa |
| dc.relation.references | Gingold E.L Cann~C.E Hasegawa~B.H, Reilly~S.M. Design considerations for simultaneous emission transmission ct scanner. | spa |
| dc.relation.references | R.E. Hendrick. \em Breast MRI: Fundamentals and Technical Aspects. Springer New York, 2007 | spa |
| dc.relation.references | Brian~F. Hutton and Michael Braun. Software for image registration: Algorithms, accuracy, efficacy. \em Seminars in Nuclear Medicine, 33(3):180--192, 2003 | spa |
| dc.relation.references | Glenn Knoll. \em Radiation Detection and Measurement. John Wiley and Sons, 2000. | spa |
| dc.relation.references | William Leo. \em Radiation Detection and Measurements. Springer-Verlag, 1987. | spa |
| dc.relation.references | M.H. Levitt. \em Spin Dynamics: Basics of Nuclear Magnetic Resonance. Wiley, 2008. | spa |
| dc.relation.references | Marek~J. Maryanski, Geoffrey~S. Ibbott, P.~Eastman, Robert~J. Schulz, and John~C. Gore. Radiation therapy dosimetry using MRI of polymer gels, 1996. | spa |
| dc.relation.references | Johan Nuyts, Girish Bal, Frank Kehren, Matthias Fenchel, Christian Michel, and Charles Watson. Completion of a truncated attenuation image from the attenuated PET emission data. \em IEEE Transactions on Medical Imaging, 32(2):237--246, 2013. | spa |
| dc.relation.references | Joseph Perl. Introduction to Geant4 Visualization Introduction to Geant4 Visualization. Technical Report January, CERN, 2014. | spa |
| dc.relation.references | Saha2013 Gopal~B. Saha. \em Physics and radiobiology of nuclear medicine. Springer-Verlag, New York, fourth edi edition, 2013. | spa |
| dc.relation.references | MARCELO MENNA~BARRETO SCHWARCKE. \em Caracteriza\cc\~ao do Gel Polim\'erico MAGIC-f para Aplica\cc\~ao em Medicina Nuclear Utilizando Imagens de Resson\^ancia Magn\'etica. PhD thesis, Universidade de Sao Paulo, 2013 | spa |
| dc.relation.references | J.~Seco and F.~Verhaegen. \em Monte Carlo Techniques in Radiation Therapy. Imaging in medical diagnosis and therapy. CRC Press, 2016. | spa |
| dc.relation.references | Cherry~SR. Shao~Y. Combined PET / CT : the historical perspective. \em Phys Med Biol, 70(42):10, 1997. | spa |
| dc.relation.references | James~A. Sorenson and Michael~E. Phelps. The Anger Camera: Performance Characteristics. \em Physics in Nuclear Medicine, pages 331--345, 1987. | spa |
| dc.relation.references | Varian~Medical Systems. Eclipse™ Treatment Planning System – New in 2012, 2012. | spa |
| dc.relation.references | Richard~E. Toohey, Michael~G. Stabin, and Evelyn~E. Watson. The AAPM/RSNA Physics Tutorial for Residents. \em RadioGraphics, 20(2):533--546, 2000. | spa |
| dc.relation.references | David~W Townsend. Combined PET / CT : the historical perspective. \em Seminars in Ultrasound, CT, and MRI, 29(4):232--235, 2009. | spa |
| dc.relation.references | Gustav~K. von Schulthess. Clinical positron emission tomography/ magnetic resonance imaging applications. \em Nuclear Medicine, 2013. | spa |
| dc.relation.references | Marijke Welvaert and Yves Rosseel. On the definition of signal-to-noise ratio and contrast-to-noise ratio for fMRI data. \em PLoS ONE, 8(11), 2013. | spa |
| dc.relation.references | J.~R. Zimmerman and W.~E. Brittin. Nuclear magnetic resonance studies in multiple phase systems: Lifetime of a water molecule in an adsorbing phase on silica gel. \em The Journal of Physical Chemistry, 61(10):1328--1333, 1957. | spa |
| dc.rights | Derechos reservados - Universidad Nacional de Colombia | spa |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.license | Atribución-NoComercial-SinDerivadas 4.0 Internacional | spa |
| dc.rights.spa | Acceso abierto | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | spa |
| dc.subject.ddc | 530 - Física | spa |
| dc.subject.proposal | MRI | eng |
| dc.subject.proposal | IRM | spa |
| dc.subject.proposal | Medical image | eng |
| dc.subject.proposal | Imagen médica | spa |
| dc.subject.proposal | Imagen híbrida | spa |
| dc.subject.proposal | Hybrid image | eng |
| dc.subject.proposal | Imagen anatómica | spa |
| dc.subject.proposal | Anatomical image | eng |
| dc.subject.proposal | Functional image | eng |
| dc.subject.proposal | Imagen funcional | spa |
| dc.title | MRI- γ Detector Hybrid System | spa |
| dc.type | Trabajo de grado - Doctorado | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_db06 | spa |
| dc.type.coarversion | http://purl.org/coar/version/c_ab4af688f83e57aa | spa |
| dc.type.content | Text | spa |
| dc.type.driver | info:eu-repo/semantics/doctoralThesis | spa |
| dc.type.version | info:eu-repo/semantics/acceptedVersion | spa |
| oaire.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |

