Prevalencia de osteoporosis posmenopáusica de muy alto riesgo en el Hospital Universitario Nacional

dc.contributor.advisorArteaga Díaz, Juan Manuel
dc.contributor.advisorMartínez Peñaloza, Daniela
dc.contributor.authorMejía Sandoval, Harvey Julián
dc.contributor.orcidMejia, Harvey [0000000176595379]spa
dc.date.accessioned2023-01-26T19:55:01Z
dc.date.available2023-01-26T19:55:01Z
dc.date.issued2023-01-25
dc.description.abstractPrevalencia de osteoporosis posmenopáusica de muy alto riesgo en el Hospital Universitario Nacional Introducción: La osteoporosis posmenopáusica de muy alto riesgo (OPMAR) incluye las pacientes que tienen una mayor probabilidad de tener fracturas a corto plazo. Se define como la presencia de 1 o más de: fracturas en los últimos 12 meses, durante el tratamiento, asociada a fármaco lesivo, más de una, T-score < -3, alto riesgo de caídas, FRAX de muy alta probabilidad. Hasta el momento ningún estudio ha determinado su frecuencia y caracterización. Objetivos: determinar la frecuencia de OPMAR en el HUN, caracterizar este grupo de pacientes, identificar la distribución de los factores de riesgo, complicaciones y tratamiento recibido. Metodología: estudio observacional, descriptivo de corte transversal. Se realizó búsqueda en sistema HOSVITAL de códigos CIE10 relacionados con osteoporosis (OP) durante 2020 - 2021. Se seleccionaron las pacientes con OP posmenopáusica atendidas en consulta externa de endocrinología. Se determinó frecuencia y caracterización del grupo de muy alto riesgo. Resultados: de 502 pacientes, 221 clasificaron como OPMAR (44%), con media de edad 72. Las comorbilidades más frecuentes fueron hipertensión arterial (32,2%), diabetes tipo 2 (11,8%), insuficiencia cardiaca (10,4%) e hiperparatiroidismo secundario (7,7%). Hubo antecedente de tabaquismo en 8,6%, consumo de inhibidores de bomba de protones en 19,5%, glucocorticoides en 12,2%. El 21,3% presentaron deficiencia de vitamina D, 10,8% reportaron caídas en el último año. 43,4% tuvieron fracturas, 20,3% en columna dorsal. 30,8% recibieron manejo con teriparatida, 14,5% como terapia inicial. Conclusiones: La OPMAR es una condición de elevada frecuencia. La edad avanzada y múltiples factores contribuyen a su aparición. El principal sitio afectado fue columna dorsal. Existe un bajo uso de terapia anabólica, la cual debe preferirse en estos casos. (Texto tomado de l a fuente)spa
dc.description.abstractPrevalence of very high risk postmenopausal osteoporosis in the national university hospital Introduction: Very high-risk postmenopausal osteoporosis (OPMAR) includes patients who have a higher probability of having fractures in the short term. It is defined as the presence of 1 or more of: fractures in the last 12 months, during treatment, associated with an injurious drug, more than one, T-score < -3, high risk of falls, FRAX with a very high probability. To date, no study has determined its frequency and characterization. Objectives: to determine the frequency of OPMAR in the HUN, to characterize this group of patients, to identify the distribution of risk factors, complications and treatment received. Methodology: observational, descriptive cross-sectional study. A search was made in the HOSVITAL system for ICD10 codes related to osteoporosis (OP) during 2020 - 2021. Patients with postmenopausal OP seen in an endocrinology outpatient clinic were selected. Frequency and characterization of the very high risk group was determined. Results: Of 502 patients, 221 were classified as OPMAR (44%), with a mean age of 72. The most frequent comorbidities were arterial hypertension (32.2%), type 2 diabetes (11.8%), heart failure (10, 4%) and secondary hyperparathyroidism (7.7%). There was a history of smoking in 8.6%, consumption of proton pump inhibitors in 19.5%, glucocorticoids in 12.2%. 21.3% presented vitamin D deficiency, 10.8% reported falls in the last year. 43.4% had fractures, 20.3% in the thoracic column. 30.8% received management with teriparatide, 14.5% as initial therapy. Conclusions: OPMAR is a condition of high frequency. Advanced age and multiple factors contribute to its appearance. The main affected site was the dorsal column. There is a low use of anabolic therapy, which should be preferred in these caseseng
dc.description.degreelevelEspecialidades Médicasspa
dc.description.degreenameEspecialista en Endocrinologíaspa
dc.description.methodsDiseño del estudio Estudio observacional descriptivo de corte transversal. Marco muestral Población a estudio: Pacientes con diagnóstico de osteoporosis atendidas en el HUN, en el servicio de consulta externa de endocrinología, registradas en el sistema HOSVITAL. Población blanco: Pacientes con diagnóstico de osteoporosis atendidas en el HUN, durante los años 2020 a 2021, en el servicio de consulta externa de endocrinología y registradas en el sistema HOSVITAL. Se obtendrá este dato a partir de la revisión de todos los diagnósticos CIE10 registrados, relacionados con osteoporosis (M800, M801, M802, M803, M804, M805, M808, M809, M810, M811, M812, M813, M814, M815, M816, M818, M819, M820, M821, M828) en el sistema HOSVITAL, durante los años 2020 a 2021. De este grupo se seleccionarán, a través de la revisión de historias clínicas las pacientes con OPMAR, se determinará la frecuencia y se realizará su caracterización. Tipo de muestreo: Se realizará un muestreo por conveniencia donde se seleccionarán solo los pacientes con diagnóstico de osteoporosis registrados en el sistema HOSVITAL, durante los años 2020 a 2021, atendidos en el HUN.spa
dc.description.researchareaEndocrinologíaspa
dc.format.extent75 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameUniversidad Nacional de Colombiaspa
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombiaspa
dc.identifier.repourlhttps://repositorio.unal.edu.co/spa
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/83147
dc.language.isospaspa
dc.publisherUniversidad Nacional de Colombiaspa
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotáspa
dc.publisher.facultyFacultad de Medicinaspa
dc.publisher.placeBogotá, Colombiaspa
dc.publisher.programBogotá - Medicina - Especialidad en Endocrinologíaspa
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacionalspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.subject.ddc610 - Medicina y saludspa
dc.subject.lembOsteoporosisspa
dc.subject.lembEnfermedad de los huesosspa
dc.subject.lembBones - diseaseseng
dc.subject.proposalosteoporosis posmenopáusicaspa
dc.subject.proposalFactores de riesgospa
dc.subject.proposalMuy alto riesgospa
dc.subject.proposalFracturas vertebralesspa
dc.subject.proposalAgentes anabólicosspa
dc.subject.proposalPostmenopausal osteoporosiseng
dc.subject.proposalRisk factorseng
dc.subject.proposalVery high riskeng
dc.subject.proposalVertebral fractureseng
dc.subject.proposalAnabolic agentseng
dc.titlePrevalencia de osteoporosis posmenopáusica de muy alto riesgo en el Hospital Universitario Nacionalspa
dc.title.translatedPrevalence of very high risk postmenopausal osteoporosis in the National University Hospitaleng
dc.typeTrabajo de grado - Especialidad Médicaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/masterThesisspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TMspa
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
dcterms.audience.professionaldevelopmentEstudiantesspa
dcterms.audience.professionaldevelopmentInvestigadoresspa
dcterms.audience.professionaldevelopmentMaestrosspa
dcterms.audience.professionaldevelopmentPúblico generalspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.awardtitlePrevalencia de osteoporosis posmenopáusica de muy alto riesgo en el Hospital Universitario Nacionalspa

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