Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida

dc.contributor.advisorUscategui Daccarett, Angélica Maríaspa
dc.contributor.authorBedoya Morales, Ana Maritzaspa
dc.contributor.researchgroupNeuroped-Unalspa
dc.contributor.subjectmatterexpertEcheverria Palacio, Carlos Mariospa
dc.date.accessioned2022-02-05T01:45:55Z
dc.date.available2022-02-05T01:45:55Z
dc.date.issued2021
dc.descriptionilustraciones, gráficas, tablasspa
dc.description.abstractIntroducción: La epilepsia es una patología importante con consecuencias neurobiológicas, cognitivas, psicológicas y sociales, entre un 10-20% de los pacientes serán refractarios a manejo farmacológico, el pobre control de crisis epilépticas tiene un impacto negativo para el individuo y su familia, generando un compromiso en la calidad de vida. Dentro de las opciones de tratamiento se encuentra la cirugía de epilepsia, que busca impactar de forma integral en los pacientes. Objetivo: Determinar el impacto en calidad de vida de los niños y adolescentes con epilepsia refractaria que han sido tratados con cirugía de epilepsia, usando como herramienta de medición la escala ECANIVAE-LICCE. Metodología: Estudio observacional, se revisaron las historias clínicas de los pacientes pediátricos ingresados al programa de cirugía de epilepsia entre enero de 2017 y diciembre de 2019, se evaluó la escala ECANIVAE-LICCE pre y postquirúrgica. Resultados: Se analizaron 24 pacientes, 91,7% con un síndrome epiléptico focal, 100% con alteraciones en neuroimagenes, en promedio requirieron el uso de 3 medicamentos de forma simultánea, el 37,5% recibieron intervenciones no farmacológicas, la mediana de edad al momento de la cirugía fue de 10.5 años, 54,2% de los pacientes quedaron libres de crisis posterior a cirugía. Continuaban con igual puntuación en la escala de calidad de vida el 54,2%, estaban en peor condición el 25% y con una mejor condición que previo a la intervención el 20,8%. Conclusiones: Los pacientes evaluados lograron disminución en la frecuencia de crisis posterior a la intervención quirúrgica, sin embargo esto no influyó en la modificación de la escala de calidad vida. (Texto tomado de la fuente).spa
dc.description.abstractIntroduction: Epilepsy is an important pathology with neurobiological, cognitive, psychological and social consequences, between 10-20% of patients will be refractory to pharmacological management, poor control of epileptic seizures has a negative impact on the individual and their family, generating a commitment to quality of life. Among the treatment options is epilepsy surgery, which seeks to have a comprehensive impact on patients. Objective: To determine the impact on the quality of life of children and adolescents with refractory epilepsy who have been treated with epilepsy surgery, using the ECANIVAE-LICCE scale as a measurement tool. Methodology: Observational study, the medical records of pediatric patients admitted to the epilepsy surgery program between January 2017 and December 2019 were reviewed, the pre and post-surgical ECANIVAE-LICCE scale was evaluated. Results: 24 patients were analyzed, 91.7% with a focal epileptic syndrome, 100% with neuroimaging alterations, on average they required the use of 3 drugs simultaneously, 37.5% received non-pharmacological interventions, the median age at the time of surgery, it was 10.5 years, 54.2% of the patients were seizure-free after surgery. 54.2% continued with the same score on the quality of life scale, 25% were in a worse condition and 20.8% were in a better condition than before the intervention. Conclusions: The evaluated patients achieved a decrease in the frequency of seizures after the surgical intervention, however it did not influence the modification of the quality of life scale.eng
dc.description.degreelevelEspecialidades Médicasspa
dc.description.degreenameEspecialista en Neuropediatríaspa
dc.description.methods-Tipo de estudio Estudio observacional con componente descriptivo y analítico de tipo corte transversal. -Población de estudio Niños y adolescentes con epilepsia refractaria que fueron valorados en el programa de cirugía de epilepsia de UNIEPILEPSIAS, durante el periodo de enero de 2017 a diciembre de 2019. -Criterios de inclusión • Edad entre 0 y 17 años y 11 meses. • Diagnóstico de epilepsia refractaria. • Ingresados en el programa de cirugía de epilepsia durante el periodo de enero de 2017 a diciembre de 2019. • Que hayan sido tratados con cualquier tipo de procedimiento quirúrgico para el tratamiento de la epilepsia. • Que hayan diligenciado la escala de calidad de vida ECAVINAE-LICCE al ingreso y a los 6 meses de la intervención. -Criterios de exclusión • Niños y adolescentes que no hayan diligenciado la escala ECANIVAE-LICCE. • Que no sean candidatos a ningún tipo de manejo quirúrgico para la epilepsia. -Diseño muestral Muestra por conveniencia de niños y adolescentes que cumplieron con los criterios de inclusión y exclusión. -Instrumento utilizado para evaluación de calidad de vida Escala ECANIVAE-LICCE según grupo de edad correspondiente: - 0 a 3 años. - 4 a 10 años. - 11 a 17 años y 11 meses. -Instrumento de recolección de la información Diseño de instrumento de recolección de datos (Anexo A). - Aspectos operativos - Identificación de pacientes: Se buscará pacientes con diagnóstico de epilepsia refractaria ingresados al programa de cirugía de epilepsia del centro UNIEPILEPSIAS, basados en los registros de la institución y las historias clínicas de los pacientes - Los datos sociodemográficos, clínicos, y los resultados de la aplicación de la escala ECAVINAE-LICCE (Anexo D) serán obtenidos a partir de la historia clínica institucional. - Los datos que no puedan recolectarse de la historia clínica, serán diligenciados a través de llamada telefónica al paciente y/o acudiente del paciente -Variables del estudio Ver tabla de descripción de variables en el Anexo C. -Programa a utilizar para análisis de datos Se digitarán los datos en una hoja de cálculo de Microsoft Excel, cuya tabulación corresponderá a lo establecido en la definición para cada variable estudiada definido en el instrumento de recolección de datos, de forma posterior se realizará un análisis estadístico con el programa Statistical Package for the Social Sciences (SPSS). -Plan de análisis de la información Se realizará un análisis univariado de las variables cualitativas en términos de frecuencias absolutas y relativas, Se determinará la distribución de estas variables como normal o no normal con el uso de la prueba estadística de normalidad de Shapiro-Wilks, con lo cual se podrá definir para las variables de distribución no normal la mediana y los percentiles, y para las variables de distribución normal se definirá la media y sus desviaciones estándar. Para el análisis bivariado de las variables cuantitativas se buscará su asociación tomando como significativa un valor de p <0.05%, la medida de asociación será el Odds ratio (OR), sobre el que se estimarán sus respectivos intervalos de confianza (IC) a 95%. Para estimar las asociaciones con variables cuantitativas se utilizará la prueba de Mann-Whitney U. Recursos -Recurso humano Para la investigación se requirió: • Estudiante investigador • Tutor • Epidemiólogo -Recursos físicos Para la realización del estudio se usaron los siguientes componentes físicos: • Computador con acceso a internet • Papelería (hojas y lapiceros) • Acceso al archivo de historias clínicas en físicospa
dc.description.notesIncluye anexosspa
dc.description.researchareaLínea de investigación en epilepsiaspa
dc.format.extentxvii, 61 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameUniversidad Nacional de Colombiaspa
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombiaspa
dc.identifier.repourlhttps://repositorio.unal.edu.co/spa
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/80888
dc.language.isospaspa
dc.publisherUniversidad Nacional de Colombiaspa
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotáspa
dc.publisher.departmentDepartamento de Pediatríaspa
dc.publisher.facultyFacultad de Medicinaspa
dc.publisher.placeBogotá, Colombiaspa
dc.publisher.programBogotá - Medicina - Especialidad en Neuropediatríaspa
dc.relation.indexedBiremespa
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.licenseAtribución-NoComercial 4.0 Internacionalspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/spa
dc.subject.ddc610 - Medicina y saludspa
dc.subject.decsSalud del Niñospa
dc.subject.decsChild Healtheng
dc.subject.decsEpilepsia/cirugíaspa
dc.subject.decsEpilepsy/surgeryeng
dc.subject.decsComodidad del Pacientespa
dc.subject.decsPatient Comforteng
dc.subject.proposalEpilepsiaspa
dc.subject.proposalPediatríaspa
dc.subject.proposalCirugía de epilepsiaspa
dc.subject.proposalCalidad de vidaspa
dc.subject.proposalEpilepsyeng
dc.subject.proposalPediatricseng
dc.subject.proposalEpilepsy surgeryeng
dc.subject.proposalQuality of lifeeng
dc.titleCaracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vidaspa
dc.title.translatedCharacterization of pediatric patients before and after epilepsy surgery: a focus on quality of lifeeng
dc.typeTrabajo de grado - Especialidad Médicaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
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dc.type.redcolhttp://purl.org/redcol/resource_type/TMspa
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
dcterms.audience.professionaldevelopmentPúblico generalspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa

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