Cáncer de tiroides: características clinicopatológicas en una serie de casos del Hospital Universitario Nacional 2017-2020

dc.contributor.advisorAcosta Forero, Bernarda Jinnethspa
dc.contributor.advisorRicaurte Guerrero, Orlandospa
dc.contributor.authorBarrero Flórez, Fabián Gonzalospa
dc.coverage.temporal2017-2020
dc.date.accessioned2023-02-10T16:13:48Z
dc.date.available2023-02-10T16:13:48Z
dc.date.issued2022
dc.descriptionilustraciones, fotografías, gráficas, tablasspa
dc.description.abstractObjetivos: Describir en una población con diagnóstico de cáncer de tiroides, las características patológicas relacionadas con comportamiento biológico y riesgo de recurrencia. Métodos: Se incluyeron casos con diagnóstico histopatológico de carcinoma de tiroides entre los años 2017 y 2020, cuyos reportes de patología fueron revisados para recopilar información respecto a las variables sociodemográficas y patológicas asociadas con recurrencia. Se registraron los datos y se cuantificaron medidas de frecuencia para la muestra en general y con las submuestras: microcarcinomas y tumores mayores de un 1 centímetro. Resultados: De los 959 casos, se presentaron con mayor frecuencia en mujeres (84.98%) y en edades entre los 40 a 59 años (46.71%), el tipo histológico más frecuente fue el papilar (95.93%), seguido por el medular (1.15%). El 40.46% de los casos correspondían a microcarcinomas, los cuales presentaban menor frecuencia de características asociadas a recurrencia en comparación con los tumores mayores de un centímetro: metástasis a ganglios linfáticos (38.15% vs 63.15%), extensión extratiroidea macroscópica (1.80% vs 8.95%), compromiso de los márgenes de sección (20.10% vs 44.04%). Dentro de los microcarcinomas con metástasis a ganglios linfáticos hay una mayor presentación a edades más tempranas y de tumores multifocales, en comparación con los que no presentan metástasis. Conclusiones: El carcinoma de tiroides es una entidad frecuente en Colombia, donde los microcarcinomas comprenden una importante proporción de los casos, y los cuales se caracterizan por presentar un comportamiento menos agresivo dado por una menor prevalencia de características asociadas a recurrencia, en comparación con tumores mayores de 1 centímetro.spa
dc.description.abstractObjectives: In a case series with diagnosis of thyroid cancer, to make a description about the clinical and pathological features, especially those which are related to biological behavior and recurrence risk. Methods: A search was performed in the archives of the pathology´s laboratory at Hospital Universitario Nacional, the cases with pathological diagnosis of thyroid carcinoma between the years of 2017 and 2020 were selected. Each report of pathology was reviewed, and the information related to sociodemográfic and pathological features were recorded in a database, and statistical measures like percentage and absolute frequencies were calculated. The results were compared against researchs performed in other countries. Results: 959 cases of thyroid carcinoma were found, 84.98% were in female patients, the most common age was between 40 and 59 years (46.71%). The papillary carcinoma was the most common histologic type (95.93%), followed by medullary carcinoma (1.15%), 40.46% were microcarcinomas, which showed less prevalence versus larger carcinomas in variables such as: lymph node metastasis (38.15% vs 63.15%), gross extrathyroidal invasion (1.80% vs 8.95%) and positive surgical margins (20.10% vs 44.04%). The microcarcinomas with lymph node metastasis tends to occur frequently in younger people and when there are multifocal. Conclusions: In Colombia the thyroid carcinoma is a common entity, and microcarcinomas are frequently observed in our hospital, and show a less aggressive phenotype than larger tumors, when comparing presence of recurrence features.eng
dc.description.degreelevelEspecialidades Médicasspa
dc.description.degreenameEspecialista en Patología Anatómica y Clínicaspa
dc.description.methodsEstudio descriptivo retrospectivospa
dc.format.extentxviii, 71 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameUniversidad Nacional de Colombiaspa
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombiaspa
dc.identifier.repourlhttps://repositorio.unal.edu.co/spa
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/83417
dc.language.isospaspa
dc.publisherUniversidad Nacional de Colombiaspa
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotáspa
dc.publisher.facultyFacultad de Medicinaspa
dc.publisher.placeBogotá, Colombiaspa
dc.publisher.programBogotá - Medicina - Especialidad en Patología Anatómica y Clínicaspa
dc.relation.indexedBiremespa
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacionalspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.subject.ddc610 - Medicina y salud::616 - Enfermedadesspa
dc.subject.decsNeoplasias de la Tiroides/patologíaspa
dc.subject.decsThyroid Neoplasms/pathologyeng
dc.subject.decsEnfermedades de la Tiroides/patologíaspa
dc.subject.decsThyroid Diseases/pathologyeng
dc.subject.decsEnfermedades de la Tiroides/epidemiologíaspa
dc.subject.decsThyroid Diseases/epidemiologyeng
dc.subject.proposalNeoplasias de la tiroidesspa
dc.subject.proposalPatologíaspa
dc.subject.proposalPathologyeng
dc.subject.proposalCarcinoma, Papillaryeng
dc.subject.proposalCarcinoma papilarspa
dc.subject.proposalInformes de casosspa
dc.subject.proposalCase reportseng
dc.subject.proposalThyroid neoplasmseng
dc.titleCáncer de tiroides: características clinicopatológicas en una serie de casos del Hospital Universitario Nacional 2017-2020spa
dc.title.translatedThyroid cancer: clinico-pathological features in a case series from Hospital Universitario Nacional 2017-2020eng
dc.typeTrabajo de grado - Especialidad Médicaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/masterThesisspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TMspa
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
dcterms.audience.professionaldevelopmentEstudiantesspa
dcterms.audience.professionaldevelopmentInvestigadoresspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa

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