Obesidad abdominal, aumenta el riesgo de pólipos colorrectales

Abstract

Objetivo: Determinar la relación entre la presencia de pólipos colonicos y la obesidad Materiales y Métodos: Es un estudio observacional analítico, de tipo transversal prospectivo, entre marzo de 2012 y junio de 2013. Un total de 405 pacientes, los cuales se tomaron del servicio de gastroenterología de tres diferentes centros hospitalarios de referencia, dos de ellos de Colombia y uno de Venezuela., 225 (55.5%) cumplían con criterios de obesidad abdominal (International Diabetes Federation, IDF), 154 (38%) presentaron pólipos durante la colonoscopía (tabla 1), de los cuales 113 (73%) (P= 0.01), cumplían con criterios de obesidad abdominal y 41 (27%) (p=0.03), no cumplían con criterios de obesidad abdominal, el análisis univariado se encontró: (OR 1.055; IC 95% 0.684 - 1.625; P=0.810), talla (OR 0.305; IC 95% 0.025 – 3.722: P=0.352), antecedentes familiares de cáncer de colon en primer grado de consanguinidad (OR 2.254; IC 95% 1.190 – 4,271; P=0.013), antecedente personales positivos para hipertensión arterial, diabetes mellitus, dislipidemia, infarto agudo de miocardio y/o enfermedad cerebrovascular (OR 1.63; IC 95% 1.092 – 2.452; P=0.017), Índice de masa corporal (IMC) (OR 1.131; IC 95% 1.073 – 1.193;P=0.000), perímetro abdominal (OR 1.053; IC 95% 1.034 – 1.071; P=0.000), Peso (OR 1.032; IC 95% 1.014 – 1.051; P=0.000), edad (OR 1.024; IC 95% 1.008 – 1.040; P=0.004), análisis de regresión logística simple OR (1.042; IC 95%1.019 – 1.065; P=0.000). Conclusion: Se encontró una asociación estadísticamente significativa entre la obesidad abdominal representada en la circunferencia de la cintura y la presencia de pólipos colonicos en la población estudiada

Abstract. Objective: To determine the relationship between the presence of colonic polyps and obesity Materials and Methods : An observational study , a prospective cross-sectional , between March 2012 and June 2013. A total of 405 patients , which were taken from the gastroenterology service of three different reference hospitals , two from Colombia and one from Venezuela, 225 (55.5 %) met criteria for abdominal obesity ( International Diabetes Federation , IDF ) , 154 ( 38 %) had polyps during colonoscopy (Table 1 ), of which 113 (73 %) ( p = 0.01) met criteria for abdominal obesity and 41 ( 27% ) (p = 0.03 ), no met criteria for abdominal obesity, univariate analysis was found ( OR 1.055 , 95% CI 0684-1625 , P = 0.810 ), height ( OR 0.305 , 95% CI 0025-3722 : P = 0.352 ), family history of cancer colon in the first degree of consanguinity (OR 2.254 , 95% CI 1190 to 4.271 , P = 0.013 ) , positive personal history for hypertension, diabetes mellitus , dyslipidemia , acute myocardial infarction and / or cerebrovascular disease (OR 1.63 ; 95% CI 1092-2452 , P = 0.017 ) , body mass index (BMI ) (OR 1.131 , 95% CI 1073-1193 , P = 0.000 ) , waist circumference (OR 1.053 , 95% CI 1034-1071 , P = 0.000 ) , weight (OR 1.032 , 95% CI 1014-1051 , P = 0.000 ) , age (OR 1.024 , 95% CI 1008-1040 , P = 0.004 ) , Simple logistic regression analysis OR ( 1.042 , 95% CI 1.019 - 1.065 , P = 0.000 ) . Conclusion : A statistically significant association between abdominal obesity shown in waist circumference and the presence of colonic polyps in the study population was found