Hallazgos ecocardiográficos en recién nacidos pretérmino con conducto arterioso permeable a la altura de Bogotá, durante los años 2016 a 2018.
Autores
Sánchez-Pinzón, Carlos Andrés
Director
Díaz Góngora, Gabriel
Márquez, Alicia
Vega Padilla, Juan David
Tipo de contenido
Trabajo de grado - Especialidad Médica
Idioma del documento
EspañolFecha de publicación
2020-01-15
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Resumen
Objetivo: Describir los hallazgos ecocardiográficos en recién nacidos pretérmino
con conducto arterioso permeable en una clínica a la altura de Bogotá durante los
años 2016 a 2018.
Pacientes y métodos: Estudio observacional, analítico, de corte transversal,
llevado a cabo en una clínica a la altura de Bogotá. Se revisaron los registros
clínicos y ecocardiográficos de una muestra de 139 neonatos proveniente de una
población de 536 neonatos pretérmino.
Resultados: El sexo masculino fue más frecuente con 56,1 %, una mediana de
edad gestacional de 33 semanas (RIQ 3 semanas), mediana de peso al nacer de
1880 gr (RIQ 700 gr) y nacidos por cesárea en el 93,5%. El 28,1% presentó CAP
persistente en el primer ecocardiograma el cual se realizó a una media de 3,6 días.
El patrón de flujo más observado fue el de ductus en cierre con 76,9%. El factor de
riesgo para la necesidad de cierre terapéutico (farmacológico o quirúrgico) después
del análisis multivariado fue la relación del diámetro ventrículo izquierdo/peso
mayor a 1 (OR 108 IC 95% 6,6; 177 valor p 0,001) y como factores protectores que
indicarían el cierre espontaneo se identificó patrón de ductus en cierre (OR 0,0009
IC 95% 0,000; 0,025 valor p 0,006) y una edad gestacional mayor a 30 semanas
(OR 0,020 IC 95% 0,001; 0,457 valor p 0,014).
Objective: To describe the echocardiographic findings in preterm infants with patent ductus arteriosus in a clinic at the height of Bogotá during the years 2016 to 2018. Patients and methods: An observational, analytical, cross-sectional study, carried out in a clinic at the height of Bogotá, the clinical and echocardiographic records of a sample of 139 infants from a population of 536 preterm infants were reviewed. Results: Male sex was more frequent with 56.1%, a median gestational age of 33 weeks (IQR 3 weeks), median birth weight of 1880 grams (IQR 700 grams) and born by caesarean section in 93.5%. 28.1% presented persistent PDA in the first echocardiogram which was performed at an average of 3.6 days. The most observed flow pattern was that of ductus at closure with 76.9%. The risk factor for therapeutic closure (pharmacological or surgical) after multivariate analysis was the ratio of left ventricle diameter/weight greater than 1 (OR 108 95% CI 6.6; 177 pvalue 0.001) and protective factors indicating spontaneous closure were identified as ductus pattern at closure (OR 0.0009 95% CI 0.000; 0.025 p-value 0.006) and gestational age greater than 30 weeks (OR 0.020 95% CI 0.001; 0.457 p-value 0.014).
Objective: To describe the echocardiographic findings in preterm infants with patent ductus arteriosus in a clinic at the height of Bogotá during the years 2016 to 2018. Patients and methods: An observational, analytical, cross-sectional study, carried out in a clinic at the height of Bogotá, the clinical and echocardiographic records of a sample of 139 infants from a population of 536 preterm infants were reviewed. Results: Male sex was more frequent with 56.1%, a median gestational age of 33 weeks (IQR 3 weeks), median birth weight of 1880 grams (IQR 700 grams) and born by caesarean section in 93.5%. 28.1% presented persistent PDA in the first echocardiogram which was performed at an average of 3.6 days. The most observed flow pattern was that of ductus at closure with 76.9%. The risk factor for therapeutic closure (pharmacological or surgical) after multivariate analysis was the ratio of left ventricle diameter/weight greater than 1 (OR 108 95% CI 6.6; 177 pvalue 0.001) and protective factors indicating spontaneous closure were identified as ductus pattern at closure (OR 0.0009 95% CI 0.000; 0.025 p-value 0.006) and gestational age greater than 30 weeks (OR 0.020 95% CI 0.001; 0.457 p-value 0.014).