Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros

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dc.contributor.advisorJairo Aureliano, Jaime Correaspa
dc.contributor.authorCarrillo Torres, Adriana Carolinaspa
dc.contributor.researchgroupCentro de Investigación en Infectología e Inmunología Veterinaria (Ci3V)spa
dc.date.accessioned2024-04-09T18:49:57Z
dc.date.available2024-04-09T18:49:57Z
dc.date.issued2023-10-01
dc.descriptionilustraciones, diagramas, fotografíasspa
dc.description.abstractLa enfermedad respiratoria bovina (ERB) provoca una considerable morbilidad y mortalidad en terneros, resultando en pérdidas económicas significativas. La ERB se caracteriza por ser un complejo donde hay interacciones entre factores medioambientales, el estado inmunológico del huésped y la presencia de agentes virales y/o bacterianos. Los agentes virales primarios asociados a ERB son el herpesvirus bovino 1 (BoHV-1), virus de la diarrea viral bovina (BVDV-1), virus de la parainfluenza bovina (BPIV3) y el virus sincitial respiratorio bovino (BRSV). Este proyecto planteó como objetivo principal la detección mediante RT-PCR / qPCR de los principales virus asociados a ERB (BRSV, BPIV3, BoHV-1 y BVDV). Para lo anterior, se colectaron muestras de tejido pulmonar (P) y raspado nasal (RN) de terneros menores a seis meses de edad provenientes de hatos lecheros, colectadas en planta de beneficio. Los resultados revelaron una tasa de positividad del 25% para BRSV en las muestras de raspado nasal (RN) por PCR. Por su parte, en el caso de BPIV3, se observó una positividad del 14,6% mediante PCR y un aumento significativo al 41,7% mediante qPCR en las muestras de RN. Al analizar las muestras de pulmón, se constató que la positividad fue del 4% mediante PCR y del 26% mediante qPCR para BPIV3. Además, se logró secuenciar el gen P del BPIV3, determinando que la cepa colombiana corresponde al genotipo A. En la evaluación histopatológica, se identificó la neumonía intersticial como el diagnóstico más común. Este estudio representa el primer reporte de BRSV y BPIV3 en Colombia, lo que lo convierte en una contribución pionera en el ámbito académico. (Texto tomado de la fuente),spa
dc.description.abstractBovine respiratory disease (BRD) causes considerable morbidity and mortality in calves, resulting in significant economic losses, characterized by a complex interaction between environmental factors, host immune status and the presence of viral and/or bacterial agents. The primary viral agents associated with BRD are bovine herpesvirus 1 (BoHV-1), bovine viral diarrhea virus (BVDV-1), bovine parainfluenza virus (BPIV3) and bovine respiratory syncytial virus (BRSV). The main objective of this project was the detection by RT-PCR/qPCR of the main viruses associated with BSE (BRSV, BPIV3, BoHV-1 and BVDV). For this purpose, samples of lung tissue (P) and nasal scraping (RN) were collected from calves under six months of age from dairy herds, collected at the processing plant. The results revealed a 25% positivity rate for BRSV in nasal scraping (NR) samples by PCR. For BPIV3, a positivity of 14.6% was observed by PCR and a significant increase to 41.7% by qPCR in NR samples. When lung samples were analyzed, positivity was found to be 4% by PCR and 26% by qPCR for BPIV3. In addition, the P gene of BPIV3 was sequenced and it was determined that the Colombian strain corresponds to genotype A. Histopathological evaluation identified interstitial pneumonia as the most common diagnosis. This study represents the first report of BRSV and BPIV3 in Colombia, which makes it a pioneering contribution in the academic field.eng
dc.description.degreelevelMaestríaspa
dc.description.degreenameMagíster en Salud Animal o Magíster en Producción Animalspa
dc.description.researchareaMicrobiología e inmunologíaspa
dc.format.extentxvi, 80 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameUniversidad Nacional de Colombiaspa
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombiaspa
dc.identifier.repourlhttps://repositorio.unal.edu.co/spa
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/85886
dc.language.isospaspa
dc.publisherUniversidad Nacional de Colombiaspa
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotáspa
dc.publisher.facultyFacultad de Medicina Veterinaria y de Zootecniaspa
dc.publisher.placeBogotá, Colombiaspa
dc.publisher.programBogotá - Medicina Veterinaria y de Zootecnia - Maestría en Salud y Producción Animalspa
dc.relation.indexedAgrosaviaspa
dc.relation.indexedAgrovocspa
dc.relation.referencesZhu YM, Shi HF, Gao YR, et al. Isolation and genetic characterization of bovine parainfluenza virus type 3 from cattle in China. Veterinary Microbiology. 2011;149(3):446-451. doi:10.1016/j.vetmic.2010.11.011spa
dc.relation.referencesBryson DG, McFerran JB, Ball HJ, Neill SD. Observations on outbreaks of respiratory disease in housed calves--(1) Epidemiological, clinical and microbiological findings. Vet Rec. 1978;103(22):485-489. doi:10.1136/vr.103.22.485spa
dc.relation.referencesEllis JA. Update on viral pathogenesis in BRD. Anim Health Res Rev. 2009;10(2):149-153. doi:10.1017/S146625230999020Xspa
dc.relation.referencesHay KE, Ambrose RCK, Morton JM, et al. Effects of exposure to Bovine viral diarrhoea virus 1 on risk of bovine respiratory disease in Australian feedlot cattle. Preventive Veterinary Medicine. 2016;126:159-169. doi:10.1016/j.prevetmed.2016.01.025spa
dc.relation.referencesMurray GM, O’Neill RG, Lee AM, et al. The bovine paranasal sinuses: Bacterial flora, epithelial expression of nitric oxide and potential role in the in-herd persistence of respiratory disease pathogens. Melcher U, ed. PLoS ONE. 2017;12(3):e0173845. doi:10.1371/journal.pone.0173845spa
dc.relation.referencesHorwood PF, Mahony TJ. Multiplex real-time RT-PCR detection of three viruses associated with the bovine respiratory disease complex. Journal of Virological Methods. 2011;171(2):360-363. doi:10.1016/j.jviromet.2010.11.020spa
dc.relation.referencesBlakebrough-Hall C, McMeniman JP, González LA. An evaluation of the economic effects of bovine respiratory disease on animal performance, carcass traits, and economic outcomes in feedlot cattle defined using four BRD diagnosis methods. J Anim Sci. 2020;98(2):skaa005. doi:10.1093/jas/skaa005spa
dc.relation.referencesGorden PJ, Plummer P. Control, Management, and Prevention of Bovine Respiratory Disease in Dairy Calves and Cows. Veterinary Clinics of North America: Food Animal Practice. 2010;26(2):243-259. doi:10.1016/j.cvfa.2010.03.004spa
dc.relation.referencesBolaños D, Donado P, Oliver Espinosa OJ. The Effect Of Management Factors On Morbidity And Mortality Calves Up To Two Months Of Age In Colombian Dairy Farms At high Altitudes. In: Vol XIX. ; 1996.spa
dc.relation.referencesEscobar Vargas A, Bonilla Quintero R, Oliver Espinosa O, Donado P. Factores de Manejo Que Afectan La Morbilidad y Mortalidad En Terneros Durante Sus Primeros Tres Meses de Vida En El Municipio de San Pedro de Los Milagros, Departamento de Antioquia. 1997.spa
dc.relation.referencesMejía Ortega G, Oliver Espinosa OJ. Estudio Sobre Los Factores Que Afectan La Morbilidad y La Mortalidad de Terneros Durante Sus Primeros Cuatro Meses de Edad En Hatos Selectos de La Sabana de Bogotá. 2005.spa
dc.relation.referencesVeit HP, Farrell RL. The anatomy and physiology of the bovine respiratory system relating to pulmonary disease. Cornell Vet. 1978;68(4):555-581.spa
dc.relation.referencesMariassy AT, Plopper CG, Dungworth DL. Characteristics of bovine lung as observed by scanning electron microscopy. Anat Rec. 1975;183(1):13-26. doi:10.1002/ar.1091830103spa
dc.relation.referencesCooper VL, Brodersen BW. Respiratory Disease Diagnostics of Cattle. Veterinary Clinics of North America: Food Animal Practice. 2010;26(2):409-416. doi:10.1016/j.cvfa.2010.04.009spa
dc.relation.referencesDubrovsky SA, Van Eenennaam AL, Karle BM, Rossitto PV, Lehenbauer TW, Aly SS. Epidemiology of bovine respiratory disease (BRD) in preweaned calves on California dairies: The BRD 10K study. Journal of Dairy Science. 2019;102(8):7306-7319. doi:10.3168/jds.2018-14774spa
dc.relation.referencesAmbrose RK, Blakebrough-Hall C, Gravel JL, Gonzalez LA, Mahony TJ. Characterisation of the Upper Respiratory Tract Virome of Feedlot Cattle and Its Association with Bovine Respiratory Disease. BIOLOGY; 2022. doi:10.20944/preprints202212.0438.v1spa
dc.relation.referencesAmbrose RK, Blakebrough-Hall C, Gravel JL, Gonzalez LA, Mahony TJ. Characterisation of the Upper Respiratory Tract Virome of Feedlot Cattle and Its Association with Bovine Respiratory Disease. Viruses. 2023;15(2):455. doi:10.3390/v15020455spa
dc.relation.referencesHause BM, Collin EA, Anderson J, Hesse RA, Anderson G. Bovine Rhinitis Viruses Are Common in U.S. Cattle with Bovine Respiratory Disease. Melcher U, ed. PLoS ONE. 2015;10(3):e0121998. doi:10.1371/journal.pone.0121998spa
dc.relation.referencesMitra N, Cernicchiaro N, Torres S, Li F, Hause BM. Metagenomic characterization of the virome associated with bovine respiratory disease in feedlot cattle identified novel viruses and suggests an etiologic role for influenza D virus. Journal of General Virology. 2016;97(8):1771-1784. doi:10.1099/jgv.0.000492spa
dc.relation.referencesNg TFF, Kondov NO, Deng X, Van Eenennaam A, Neibergs HL, Delwart E. A Metagenomics and Case-Control Study To Identify Viruses Associated with Bovine Respiratory Disease. Perlman S, ed. J Virol. 2015;89(10):5340-5349. doi:10.1128/JVI.00064-15spa
dc.relation.referencesNissly RH, Zaman N, Ibrahim PAS, et al. Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD): Emerging role of orthomyxoviruses in the pathogenesis of BRD. Virology. 2020;551:10-15. doi:10.1016/j.virol.2020.08.014spa
dc.relation.referencesPanciera RJ, Confer AW. Pathogenesis and Pathology of Bovine Pneumonia. Veterinary Clinics of North America: Food Animal Practice. 2010;26(2):191-214. doi:10.1016/j.cvfa.2010.04.001spa
dc.relation.referencesBaltimore classification ~ ViralZone. Accessed April 24, 2021. https://viralzone.expasy.org/254spa
dc.relation.referencesTaxon Details | ICTV. Accessed February 10, 2023. https://ictv.global/taxonomy/taxondetails?taxnode_id=202101650spa
dc.relation.referencesGuzman E, Taylor G. Immunology of bovine respiratory syncytial virus in calves. Molecular Immunology. 2015;66(1):48-56. doi:10.1016/j.molimm.2014.12.004spa
dc.relation.referencesFurze J, Wertz G, Lerch R, Taylor G. Antigenic heterogeneity of the attachment protein of bovine respiratory syncytial virus. J Gen Virol. 1994;75 ( Pt 2):363-370. doi:10.1099/0022-1317-75-2-363spa
dc.relation.referencesSchrijver RS, Daus F, Kramps JA, et al. Subgrouping of bovine respiratory syncytial virus strains detected in lung tissue. Vet Microbiol. 1996;53(3-4):253-260. doi:10.1016/s0378-1135(96)01223-0spa
dc.relation.referencesLarsen LE, Uttenthal A, Arctander P, et al. Serological and genetic characterisation of bovine respiratory syncytial virus (BRSV) indicates that Danish isolates belong to the intermediate subgroup: no evidence of a selective effect on the variability of G protein nucleotide sequence by prior cell culture adaption and passages in cell culture or calves. Vet Microbiol. 1998;62(4):265-279. doi:10.1016/s0378-1135(98)00226-0spa
dc.relation.referencesMallipeddi SK, Samal SK. Sequence variability of the glycoprotein gene of bovine respiratory syncytial virus. J Gen Virol. 1993;74 ( Pt 9):2001-2004. doi:10.1099/0022-1317-74-9-2001spa
dc.relation.referencesYaegashi G, Seimiya YM, Seki Y, Tsunemitsu H. Genetic and antigenic analyses of bovine respiratory syncytial virus detected in Japan. J Vet Med Sci. 2005;67(2):145-150. doi:10.1292/jvms.67.145spa
dc.relation.referencesJia S, Yao X, Yang Y, et al. Isolation, identification, and phylogenetic analysis of subgroup III strain of bovine respiratory syncytial virus contributed to outbreak of acute respiratory disease among cattle in Northeast China. Virulence. 2021;12(1):404-414. doi:10.1080/21505594.2021.1872178spa
dc.relation.referencesYazici Z, Ozan E, Tamer C, et al. Circulation of Indigenous Bovine Respiratory Syncytial Virus Strains in Turkish Cattle: The First Isolation and Molecular Characterization. Animals. 2020;10(9):1700. doi:10.3390/ani10091700spa
dc.relation.referencesLeme RA, Dall Agnol AM, Balbo LC, et al. Molecular characterization of Brazilian wild-type strains of bovine respiratory syncytial virus reveals genetic diversity and a putative new subgroup of the virus. Veterinary Quarterly. 2020;40(1):83-96.doi:10.1080/01652176.2020.1733704spa
dc.relation.referencesKlem TB, Rimstad E, Stokstad M. Occurrence and phylogenetic analysis of bovine respiratory syncytial virus in outbreaks of respiratory disease in Norway. BMC Vet Res. 2014;10(1):15. doi:10.1186/1746-6148-10-15spa
dc.relation.referencesValarcher JF, Schelcher F, Bourhy H. Evolution of bovine respiratory syncytial virus. J Virol. 2000;74(22):10714-10728. doi:10.1128/jvi.74.22.10714-10728.2000spa
dc.relation.referencesValarcher JF, Taylor G. Bovine respiratory syncytial virus infection. Vet Res. 2007;38(2):153-180. doi:10.1051/vetres:2006053spa
dc.relation.referencesSwiss Institute of Bioinformatics. Orthopneumovirus ~ ViralZone. Orthopneumovirus. Published 2023. Accessed August 1, 2023. https://viralzone.expasy.org/90?outline=all_by_speciesspa
dc.relation.referencesStott EJ, Thomas LH, Collins AP, et al. A survey of virus infections of the respiratory tract of cattle and their association with disease. J Hyg (Lond). 1980;85(2):257-270. Accessed April 27, 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133932/spa
dc.relation.referencesElvander M. Severe respiratory disease in dairy cows caused by infection with bovine respiratory syncytial virus. Vet Rec. 1996;138(5):101-105. doi:10.1136/vr.138.5.101spa
dc.relation.referencesHussain KJ, Al-Farwachi MI, Hassan SD. Seroprevalence and risk factors of bovine respiratory syncytial virus in cattle in the Nineveh Governorate, Iraq. Vet World. 2019;12(11):1862-1865. doi:10.14202/vetworld.2019.1862-1865spa
dc.relation.referencesFigueroa-Chávez D, Segura-Correa JC, García-Márquez LJ, Pescador-Rubio A, Valdivia-Flores AG. Detection of antibodies and risk factors for infection with bovine respiratory syncytial virus and parainfluenza virus 3 in dual-purpose farms in Colima, Mexico. Trop Anim Health Prod. 2012;44(7):1417-1421. doi:10.1007/s11250-012-0081-9spa
dc.relation.referencesKimman TG, Zimmer GM, Westenbrink F, Mars J, van Leeuwen E. Epidemiological study of bovine respiratory syncytial virus infections in calves: influence of maternal antibodies on the outcome of disease. Vet Rec. 1988;123(4):104-109. doi:10.1136/vr.123.4.104spa
dc.relation.referencesCosta R, Caffarena D, Mirazo S, Diab S. Neumonía por el virus respiratorio sincitial bovino (BRSV) en bovinos lecheros de Colonia, Uruguay. In: ; 2017. https://www.researchgate.net/publication/317648662_Neumonia_por_el_virus_respiratorio_sincitial_bovino_BRSV_en_bovinos_lecheros_de_Colonia_Uruguayspa
dc.relation.referencesVan der Poel WHM, Kramps JA, Middel WGJ, Van Oirschot JT, Brand A. Dynamics of bovine respiratory syncytial virus infections: a longitudinal epidemiological study in dairy herds. Archives of Virology. 1993;133(3):309-321. doi:10.1007/BF01313771spa
dc.relation.referencesViuff B, Uttenthal A, Tegtmeier C, Alexandersen S. Sites of replication of bovine respiratory syncytial virus in naturally infected calves as determined by in situ hybridization. Vet Pathol. 1996;33(4):383-390. doi:10.1177/030098589603300403spa
dc.relation.referencesSchlender J, Zimmer G, Herrler G, Conzelmann KK. Respiratory Syncytial Virus (RSV) Fusion Protein Subunit F2, Not Attachment Protein G, Determines the Specificity of RSV Infection. J Virol. 2003;77(8):4609-4616. doi:10.1128/JVI.77.8.4609-4616.2003spa
dc.relation.referencesViuff B, Tjørnehøj K, Larsen LE, et al. Replication and Clearance of Respiratory Syncytial Virus. The American Journal of Pathology. 2002;161(6):2195-2207. doi:10.1016/S0002-9440(10)64496-3spa
dc.relation.referencesEckardt-Michel J, Lorek M, Baxmann D, Grunwald T, Keil GM, Zimmer G. The Fusion Protein of Respiratory Syncytial Virus Triggers p53-Dependent Apoptosis. J Virol. 2008;82(7):3236-3249. doi:10.1128/JVI.01887-07spa
dc.relation.referencesHorwood PF, Gravel JL, Mahony TJ. Identification of two distinct bovine parainfluenza virus type 3 genotypes. Journal of General Virology. 2008;89(7):1643-1648. doi:10.1099/vir.0.2008/000026-0spa
dc.relation.referencesMurphy F, Gibbs E, Horzinek M, Studdert M. Veterinary Virology: The Third Edition. Vol 24.; 2000.spa
dc.relation.referencesAlatorre-García TA, Fonseca-Coronado S, González-Candelas F. Homologous recombination as a mechanism of genetic changes in bovine parainfluenza-3 virus. Veterinary Microbiology. 2021;261:109185. doi:10.1016/j.vetmic.2021.109185spa
dc.relation.referencesSakai Y, Suzu S, Shioda T, Shibuta H. Nucleotide sequence of the bovine parainfluenza 3 virus genome: its 3’ end and the genes of NP, P, C and M proteins. Nucleic Acids Res. 1987;15(7):2927-2944. Accessed August 15, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC340707/spa
dc.relation.referencesNeill JD, Ridpath JF, Valayudhan BT. Identification and genome characterization of genotype B and genotype C bovine parainfluenza type 3 viruses isolated in the United States. BMC Vet Res. 2015;11:112. doi:10.1186/s12917-015-0431-8spa
dc.relation.referencesSobhy NM, Mor SK, Bastawecy IM, Fakhry HM, Youssef CRB, Goyal SM. Surveillance, isolation and complete genome sequence of bovine parainfluenza virus type 3 in Egyptian cattle. International Journal of Veterinary Science and Medicine. 2017;5(1):8-13. doi:10.1016/j.ijvsm.2017.02.004spa
dc.relation.referencesOem JK, Lee EY, Lee KK, Kim SH, Lee MH, Hyun BH. Molecular characterization of a Korean bovine parainfluenza virus type 3 isolate. Vet Microbiol. 2013;162(1):224-227. doi:10.1016/j.vetmic.2012.10.013spa
dc.relation.referencesKonishi M, Ohkura T, Shimizu M, Akiyama M, Kameyama K ichiro, Takeuchi K. Complete Genome Sequence of the First Isolate of Genotype C Bovine Parainfluenza Virus Type 3 in Japan. Genome Announc. 2014;2(6):e01215-14. doi:10.1128/genomeA.01215-14spa
dc.relation.referencesFulton RW. Viruses in Bovine Respiratory Disease in North America. Vet Clin North Am Food Anim Pract. 2020;36(2):321-332. doi:10.1016/j.cvfa.2020.02.004spa
dc.relation.referencesMaidana SS, Lomonaco PM, Combessies G, et al. Isolation and characterization of bovine parainfluenza virus type 3 from water buffaloes (Bubalus bubalis) in Argentina. BMC Vet Res. 2012;8(1):83. doi:10.1186/1746-6148-8-83spa
dc.relation.referencesSwiss Institute of Bioinformatics. Respirovirus ~ ViralZone. Viral Zone. Published 2023. Accessed August 1, 2023. https://viralzone.expasy.org/87?outline=all_by_speciesspa
dc.relation.referencesReisinger RC, Heddleston KL, Manthei CA. A myxovirus (SF-4) associated with shipping fever of cattle. J Am Vet Med Assoc. 1959;135(3):147-152.spa
dc.relation.referencesEllis JA. Bovine Parainfluenza-3 Virus. Veterinary Clinics of North America: Food Animal Practice. 2010;26(3):575-593. doi:10.1016/j.cvfa.2010.08.002spa
dc.relation.referencesKapil S, Basaraba RJ. Infectious Bovine Rhinotracheitis, Parainfluenza-3, and Respiratory Coronavirus. Veterinary Clinics of North America: Food Animal Practice. 1997;13(3):455-469. doi:10.1016/S0749-0720(15)30308-Xspa
dc.relation.referencesAllen JW, Viel L, Bateman KG, Nagy E, Røsendal S, Shewen PE. Serological titers to bovine herpesvirus 1, bovine viral diarrhea virus, parainfluenza 3 virus, bovine respiratory syncytial virus and Pasteurella haemolytica in feedlot calves with respiratory disease: associations with bacteriological and pulmonary cytological variables. Can J Vet Res. 1992;56(4):281-288.spa
dc.relation.referencesFulton RW, Purdy CW, Confer AW, et al. Bovine viral diarrhea viral infections in feeder calves with respiratory disease: interactions with Pasteurella spp., parainfluenza-3 virus, and bovine respiratory syncytial virus. Can J Vet Res. 2000;64(3):151-159.spa
dc.relation.referencesDurham PJK, Hassard LE. Prevalence of antibodies to infectious bovine rhinotracheitis, parainfluenza 3, bovine respiratory syncytial, and bovine viral diarrhea viruses in cattle in Saskatchewan and Alberta. Can Vet J. 1990;31(12):815-820. Accessed June 18, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1480901/spa
dc.relation.referencesKestaitiene K, Salomskas A, Jacevičius E, et al. Prevalence of bovine parainfluenza 3 and respiratory syncytial virus in lithuanian cattle. Veterinarija ir Zootechnika. 2010;47:32-36.spa
dc.relation.referencesLyon M, Leroux C, Greenland T, Chastang J, Patet J, Mornex JF. Presence of a unique parainfluenza virus 3 strain identified by RT-PCR in visna-maedi virus infected sheep. Veterinary Microbiology. 1997;57(2-3):95-104. doi:10.1016/S0378-1135(97)00104-1spa
dc.relation.referencesYener Z, Sağlam YS, Timurkaan N, Ilhan F. Immunohistochemical detection of parainfluenza type 3 virus antigens in paraffin sections of pneumonic caprine lungs. J Vet Med A Physiol Pathol Clin Med. 2005;52(6):268-271. doi:10.1111/j.1439-0442.2005.00724.xspa
dc.relation.referencesOhsawa K, Yamada A, Takeuchi K, Watanabe Y, Miyata H, Sato H. Genetic characterization of parainfluenza virus 3 derived from guinea pigs. J Vet Med Sci. 1998;60(8):919-922. doi:10.1292/jvms.60.919spa
dc.relation.referencesZarnke RL, Erickson GA. Serum antibody prevalence of parainfluenza 3 virus in a free-ranging bison (Bison bison) herd from Alaska. J Wildl Dis. 1990;26(3):416-419. doi:10.7589/0090-3558-26.3.416spa
dc.relation.referencesFischer-Tenhagen C, Hamblin C, Quandt S, Frölich K. Serosurvey for selected infectious disease agents in free-ranging black and white rhinoceros in Africa. J Wildl Dis. 2000;36(2):316-323. doi:10.7589/0090-3558-36.2.316spa
dc.relation.referencesThorsen J, Henderson JP. Survey for antibody to infectious bovine rhinotracheitis (IBR), bovine virus diarrhea (BVD) and parainfluenza 3 (PI3) in moose sera. J Wildl Dis. 1971;7(2):93-95. doi:10.7589/0090-3558-7.2.93spa
dc.relation.referencesHaanes EJ, Guimond P, Wardley R. The bovine parainfluenza virus type-3 (BPIV-3) hemagglutinin/neuraminidase glycoprotein expressed in baculovirus protects calves against experimental BPIV-3 challenge. Vaccine. 1997;15(6-7):730-738. doi:10.1016/S0264-410X(96)00231-9spa
dc.relation.referencesSwift BL, Trueblood MS. The present status of the role of the Parainfluenza-3 (PI-3) virus in fetal disease of cattle and sheep. Theriogenology. 1974;2(4):101-107. doi:10.1016/0093-691X(74)90004-1spa
dc.relation.referencesLamb RA, Paterson RG, Jardetzky TS. Paramyxovirus membrane fusion: Lessons from the F and HN atomic structures. Virology. 2006;344(1):30-37. doi:10.1016/j.virol.2005.09.007spa
dc.relation.referencesEllis JA. Bovine Parainfluenza-3 Virus. Veterinary Clinics of North America: Food Animal Practice. 2010;26(3):575-593. doi:10.1016/j.cvfa.2010.08.002spa
dc.relation.referencesBryson DG, McNulty MS, Ball HJ, Neill SD, Connor TJ, Cush PF. The experimental production of pneumonia in calves by intranasal inoculation of parainfluenza type III virus. Vet Rec. 1979;105(25-26):566-573.spa
dc.relation.referencesOgunbiyi PO, Black WD, Eyre P. Parainfluenza-3 virus-induced enhancement of histamine release from calf lung mast cells--effect of levamisole. J Vet Pharmacol Ther. 1988;11(4):338-344. doi:10.1111/j.1365-2885.1988.tb00193.xspa
dc.relation.referencesSlauson DO, Lay JC, Castleman WL, Neilsen NR. Alveolar Macrophage Phagocytic Kinetics Following Pulmonary Parainfluenza-3 Virus Infection. Journal of Leukocyte Biology. 1987;41(5):412-420. doi:10.1002/jlb.41.5.412spa
dc.relation.referencesBasaraba RJ, Brown PR, Laegreid WW, Silflow RM, Evermann JF, Leid RW. Suppression of lymphocyte proliferation by parainfluenza virus type 3-infected bovine alveolar macrophages. Immunology. 1993;79(2):179-188.spa
dc.relation.referencesNuijten P, Cleton N, van der Loop J, Makoschey B, Pulskens W, Vertenten G. Early Activation of the Innate Immunity and Specific Cellular Immune Pathways after Vaccination with a Live Intranasal Viral Vaccine and Challenge with Bovine Parainfluenza Type 3 Virus. Vaccines. 2022;10(1):104. doi:10.3390/vaccines10010104spa
dc.relation.referencesSmith DB, Meyers G, Bukh J, et al. Proposed revision to the taxonomy of the genus Pestivirus, family Flaviviridae. J Gen Virol. 2017;98(8):2106-2112. doi:10.1099/jgv.0.000873spa
dc.relation.referencesRivas J, Hasanaj A, Deblon C, Gisbert P, Garigliany MM. Genetic diversity of Bovine Viral Diarrhea Virus in cattle in France between 2018 and 2020. Front Vet Sci. 2022;9:1028866. doi:10.3389/fvets.2022.1028866spa
dc.relation.referencesDeng M, Chen N, Guidarini C, et al. Prevalence and genetic diversity of bovine viral diarrhea virus in dairy herds of China. Veterinary Microbiology. 2020;242:108565. doi:10.1016/j.vetmic.2019.108565spa
dc.relation.referencesWalker PJ, Siddell SG, Lefkowitz EJ, et al. Changes to virus taxonomy and the Statutes ratified by the International Committee on Taxonomy of Viruses (2020). Arch Virol. 2020;165(11):2737-2748. doi:10.1007/s00705-020-04752-xspa
dc.relation.referencesDecaro N. HoBi-Like Pestivirus and Reproductive Disorders. Frontiers in Veterinary Science. 2020;7. Accessed March 12, 2023. https://www.frontiersin.org/articles/10.3389/fvets.2020.622447spa
dc.relation.referencesGiammarioli M, Ridpath JF, Rossi E, Bazzucchi M, Casciari C, De Mia GM. Genetic detection and characterization of emerging HoBi-like viruses in archival foetal bovine serum batches. Biologicals. 2015;43(4):220-224. doi:10.1016/j.biologicals.2015.05.009spa
dc.relation.referencesYeşilbağ K, Alpay G, Becher P. Variability and Global Distribution of Subgenotypes of Bovine Viral Diarrhea Virus. Viruses. 2017;9(6):128. doi:10.3390/v9060128spa
dc.relation.referencesBecher P, Orlich M, König M, Thiel HJ. Nonhomologous RNA Recombination in Bovine Viral Diarrhea Virus: Molecular Characterization of a Variety of Subgenomic RNAs Isolated during an Outbreak of Fatal Mucosal Disease. J Virol. 1999;73(7):5646-5653.spa
dc.relation.referencesTautz N, Tews BA, Meyers G. Chapter Two - The Molecular Biology of Pestiviruses. In: Kielian M, Maramorosch K, Mettenleiter TC, eds. Advances in Virus Research. Vol 93. Academic Press; 2015:47-160. doi:10.1016/bs.aivir.2015.03.002spa
dc.relation.referencesLazar C, Zitzmann N, Dwek RA, Branza-Nichita N. The pestivirus Erns glycoprotein interacts with E2 in both infected cells and mature virions. Virology. 2003;314(2):696-705. doi:https://doi-org.ezproxy.unal.edu.co/10.1016/S0042-6822(03)00510-5spa
dc.relation.referencesSwiss Institute of Bioinformatics. Pestivirus ~ ViralZone. Viral Zone. Published 2023. Accessed March 13, 2023. https://viralzone.expasy.org/39spa
dc.relation.referencesRichter V, Lebl K, Baumgartner W, Obritzhauser W, Käsbohrer A, Pinior B. A systematic worldwide review of the direct monetary losses in cattle due to bovine viral diarrhoea virus infection. The Veterinary Journal. 2017;220:80-87. doi:10.1016/j.tvjl.2017.01.005spa
dc.relation.referencesPeterhans E, Schweizer M. BVDV: A pestivirus inducing tolerance of the innate immune response. Biologicals. 2013;41(1):39-51. doi:10.1016/j.biologicals.2012.07.006spa
dc.relation.referencesWaldner CL, Kennedy RI. Associations between health and productivity in cow-calf beef herds and persistent infection with bovine viral diarrhea virus, antibodies against bovine viral diarrhea virus, or antibodies against infectious bovine rhinotracheitis virus in calves. Am J Vet Res. 2008;69(7):916-927. doi:10.2460/ajvr.69.7.916spa
dc.relation.referencesKnapek KJ, Georges HM, Van Campen H, et al. Fetal Lymphoid Organ Immune Responses to Transient and Persistent Infection with Bovine Viral Diarrhea Virus. Viruses. 2020;12(8):816. doi:10.3390/v12080816spa
dc.relation.referencesHarding MJ, Cao X, Shams H, et al. Role of bovine viral diarrhea virus biotype in the establishment of fetal infections. American Journal of Veterinary Research. 2002;63(10):1455-1463. doi:10.2460/ajvr.2002.63.1455spa
dc.relation.referencesRidpath J. The Contribution of Infections with Bovine Viral Diarrhea Viruses to Bovine Respiratory Disease. Veterinary Clinics of North America: Food Animal Practice. 2010;26(2):335-348. doi:10.1016/j.cvfa.2010.04.003spa
dc.relation.referencesFulton RW, Hessman BE, Ridpath JF, et al. Multiple diagnostic tests to identify cattle with Bovine viral diarrhea virus and duration of positive test results in persistently infected cattle. Can J Vet Res. 2009;73(2):117-124. Accessed July 2, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666316/spa
dc.relation.referencesChase CCL. The impact of BVDV infection on adaptive immunity. Biologicals. 2013;41(1):52-60. doi:10.1016/j.biologicals.2012.09.009spa
dc.relation.referencesRan X, Chen X, Ma L, et al. A systematic review and meta-analysis of the epidemiology of bovine viral diarrhea virus (BVDV) infection in dairy cattle in China. Acta Tropica. 2019;190:296-303. doi:10.1016/j.actatropica.2018.08.031spa
dc.relation.referencesMartin SW, Bohac JG. The association between serological titers in infectious bovine rhinotracheitis virus, bovine virus diarrhea virus, parainfluenza-3 virus, respiratory syncytial virus and treatment for respiratory disease in Ontario feedlot calves. Can J Vet Res. 1986;50(3):351-358. Accessed July 2, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1255225/spa
dc.relation.referencesO’Connor A, Martin SW, Nagy E, Menzies P, Harland R. The relationship between the occurrence of undifferentiated bovine respiratory disease and titer changes to bovine coronavirus and bovine viral diarrhea virus in 3 Ontario feedlots. Can J Vet Res. 2001;65(3):137-142. Accessed July 2, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189666/spa
dc.relation.referencesDeng M, Ji S, Fei W, et al. Prevalence Study and Genetic Typing of Bovine Viral Diarrhea Virus (BVDV) in Four Bovine Species in China. PLoS One. 2015;10(4):e0121718. doi:10.1371/journal.pone.0121718spa
dc.relation.referencesCasaubon J, Vogt HR, Stalder H, Hug C, Ryser-Degiorgis MP. Bovine viral diarrhea virus in free-ranging wild ruminants in Switzerland: low prevalence of infection despite regular interactions with domestic livestock. BMC Vet Res. 2012;8:204. doi:10.1186/1746-6148-8-204spa
dc.relation.referencesPeterhans E, Jungi TW, Schweizer M. BVDV and innate immunity. Biologicals. 2003;31(2):107-112. doi:10.1016/S1045-1056(03)00024-1spa
dc.relation.referencesRajput MKS, Darweesh MF, Braun LJ, Mansour SMG, Chase CCL. Comparative humoral immune response against cytopathic or non-cytopathic bovine viral diarrhea virus infection. Research in Veterinary Science. 2020;129:109-116. doi:10.1016/j.rvsc.2020.01.012spa
dc.relation.referencesFulton RW, d’Offay JM, Eberle R, et al. Bovine herpesvirus-1: Evaluation of genetic diversity of subtypes derived from field strains of varied clinical syndromes and their relationship to vaccine strains. Vaccine. 2015;33(4):549-558. doi:10.1016/j.vaccine.2014.11.033spa
dc.relation.referencesMetzler AE, Schudel AA, Engels M. Bovine herpesvirus 1: Molecular and antigenic characteristics of variant viruses isolated from calves with neurological disease. Archives of Virology. 1986;87(3-4):205-217. doi:10.1007/BF01315300spa
dc.relation.referencesMetzler AE, Matile H, Gassmann U, Engels M, Wyler R. European isolates of bovine herpesvirus 1: A comparison of restriction endonuclease sites, polypeptides, and reactivity with monoclonal antibodies. Archives of Virology. 1985;85(1-2):57-69. doi:10.1007/BF01317006spa
dc.relation.referencesBiswas S, Bandyopadhyay S, Dimri U, Patra PH. Bovine herpesvirus-1 (BHV-1) - a re-emerging concern in livestock: a revisit to its biology, epidemiology, diagnosis, and prophylaxis. Vet Q. 2013;33(2):68-81. doi:10.1080/01652176.2013.799301spa
dc.relation.referencesMuylkens B, Thiry J, Kirten P, Schynts F, Thiry E. Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis. Vet Res. 2007;38(2):181-209. doi:10.1051/vetres:2006059spa
dc.relation.referencesAlphaherpesvirinae ~ ViralZone. Accessed February 20, 2023. https://viralzone.expasy.org/15spa
dc.relation.referencesGuo W, Xie J, Liu J, Chen H, Jung YS. The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in China. Frontiers in Microbiology. 2022;13.spa
dc.relation.referencesThiry J, Keuser V, Muylkens B, et al. Ruminant alphaherpesviruses related to bovine herpesvirus 1. Vet Res. 2006;37(2):169-190. doi:10.1051/vetres:2005052spa
dc.relation.referencesSilvestro C, Bratanich A. The latency related gene of bovine herpesvirus types 1 and 5 and its modulation of cellular processes. Arch Virol. 2016;161(12):3299-3308. doi:10.1007/s00705-016-3067-5spa
dc.relation.referencesJones C, Geiser V, Henderson G, et al. Functional analysis of bovine herpesvirus 1 (BHV-1) genes expressed during latency. Veterinary Microbiology. 2006;113(3):199-210. doi:10.1016/j.vetmic.2005.11.009spa
dc.relation.referencesRuiz J, Jaime J, Vera V. Latencia del herpesvirus bovino-1: el papel de los transcritos relacionados con latencia (RL). Acta Biológica Colombiana. 2008;13(1):3-22.spa
dc.relation.referencesMartínez Cuesta L, Nieto Farías MV, Romeo F, Verna A, Pérez S. Expression of apoptosis-related genes at different stages of BoHV-1 and 5 infection of bovine neural tissue. Comparative Immunology, Microbiology and Infectious Diseases. 2022;90-91:101906. doi:10.1016/j.cimid.2022.101906spa
dc.relation.referencesSwiss Institute of Bioinformatics. Alphaherpesvirinae ~ ViralZone. Published 2023. Accessed February 20, 2023. https://viralzone.expasy.org/15spa
dc.relation.referencesFlint J, Racaniello VR, Rall GF, Hatziioannou T, Skalka AM. Principles of Virology, Volume 1: Molecular Biology. Vol 1. John Wiley & Sons; 2020.spa
dc.relation.referencesThiry J, Keuser V, Muylkens B, et al. Ruminant alphaherpesviruses related to bovine herpesvirus 1. Vet Res. 2006;37(2):169-190. doi:10.1051/vetres:2005052spa
dc.relation.referencesStraub OC. Advances in BHV1 (IBR) research. Dtsch Tierarztl Wochenschr. 2001;108(10):419-422.spa
dc.relation.referencesOMSA - Organización Mundial de Sanidad Animal. Código Sanitario para los Animales Terrestres. Capítulo 11.8. Rinotraqueítis Infecciosa Bovina/ Vulvovaginitis Pustular Infecciosa. OMSA - Organización Mundial de Sanidad Animal. Published 2022.spa
dc.relation.referencesInstituto Colombiano Agropecuario - ICA. Resolución 3714 de 2015 “Por la cual se establecen las enfermedades de declaración obligatoria en Colombia". Published 2015. Accessed August 1, 2023. https://www.ica.gov.co/normatividad/normas-ica/resoluciones-oficinas-nacionales/2015/2015r3714spa
dc.relation.referencesRaaperi K, Orro T, Viltrop A. Epidemiology and control of bovine herpesvirus 1 infection in Europe. The Veterinary Journal. 2014;201(3):249-256. doi:10.1016/j.tvjl.2014.05.040spa
dc.relation.referencesSayers RG, Byrne N, O’Doherty E, Arkins S. Prevalence of exposure to bovine viral diarrhoea virus (BVDV) and bovine herpesvirus-1 (BoHV-1) in Irish dairy herds. Research in Veterinary Science. 2015;100:21-30. doi:10.1016/j.rvsc.2015.02.011spa
dc.relation.referencesRomero Salas D, Ahuja Aguirre C, Montiel Palacios F, García Vázquez Z, Cruz Romero A, Aguilar Domínguez M. Seroprevalence and risk factors associated with infectious bovine rhinotracheitis in unvaccinated cattle in southern Veracruz, Mexico. http://www.academicjournals.org/AJMR. 2013;7(17):1716-1722.spa
dc.relation.referencesCampos FS, Franco AC, Hübner SO, et al. High prevalence of co-infections with bovine herpesvirus 1 and 5 found in cattle in southern Brazil. Veterinary Microbiology. 2009;139(1):67-73. doi:10.1016/j.vetmic.2009.05.015spa
dc.relation.referencesJones C, Chowdhury S. A review of the biology of bovine herpesvirus type 1 (BHV-1), its role as a cofactor in the bovine respiratory disease complex and development of improved vaccines. Animal Health Research Reviews. Published online 2007.spa
dc.relation.referencesHinkley S, Hill AB, Srikumaran S. Bovine herpesvirus-1 infection affects the peptide transport activity in bovine cells. Virus Res. 1998;53(1):91-96. doi:10.1016/s0168-1702(97)00128-7spa
dc.relation.referencesWinkler MT, Doster A, Jones C. Bovine herpesvirus 1 can infect CD4(+) T lymphocytes and induce programmed cell death during acute infection of cattle. J Virol. 1999;73(10):8657-8668. doi:10.1128/JVI.73.10.8657-8668.1999spa
dc.relation.referencesHariharan MJ, Nataraj C, Srikumaran S. Down regulation of murine MHC class I expression by bovine herpesvirus 1. Viral Immunol. 1993;6(4):273-284. doi:10.1089/vim.1993.6.273spa
dc.relation.referencesJones C. Herpes Simplex Virus Type 1 and Bovine Herpesvirus 1 Latency. Clin Microbiol Rev. 2003;16(1):79-95. doi:10.1128/CMR.16.1.79-95.2003spa
dc.relation.referencesSchang LM, Jones C. Analysis of bovine herpesvirus 1 transcripts during a primary infection of trigeminal ganglia of cattle. J Virol. 1997;71(9):6786-6795. doi:10.1128/JVI.71.9.6786-6795.1997spa
dc.relation.referencesInman M, Lovato L, Doster A, Jones C. A mutation in the latency-related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves. J Virol. 2002;76(13):6771-6779. doi:10.1128/jvi.76.13.6771-6779.2002spa
dc.relation.referencesCiacci-Zanella J, Stone M, Henderson G, Jones C. The Latency-Related Gene of Bovine Herpesvirus 1 Inhibits Programmed Cell Death. J Virol. 1999;73(12):9734-9740. Accessed July 7, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC113020/spa
dc.relation.referencesSilva MS, Brum MCS, Loreto ELS, Weiblen R, Flores EF. Molecular and antigenic characterization of Brazilian bovine herpesvirus type 1 isolates recovered from the brain of cattle with neurological disease. Virus Research. 2007;129(2):191-199. doi:10.1016/j.virusres.2007.07.014spa
dc.relation.referencesMarin MS, Leunda MR, Verna AE, Morán PE, Odeón AC, Pérez SE. Distribution of bovine herpesvirus type 1 in the nervous system of experimentally infected calves. The Veterinary Journal. 2016;209:82-86. doi:10.1016/j.tvjl.2015.10.034spa
dc.relation.referencesDonovan GA, Dohoo IR, Montgomery DM, Bennett FL. Calf and disease factors affecting growth in female holstein calves in Florida, USA. Preventive Veterinary Medicine. 1998;33(1-4):1-10. doi:10.1016/S0167-5877(97)00059-7spa
dc.relation.referencesVirtala AM, Gröhn YT, Mechor GD, Erb HN. The effect of maternally derived immunoglobulin G on the risk of respiratory disease in heifers during the first 3 months of life. Prev Vet Med. 1999;39(1):25-37. doi:10.1016/s0167-5877(98)00140-8spa
dc.relation.referencesWindeyer MC, Leslie KE, Godden SM, Hodgins DC, Lissemore KD, LeBlanc SJ. Factors associated with morbidity, mortality, and growth of dairy heifer calves up to 3 months of age. Preventive Veterinary Medicine. 2014;113(2):231-240. doi:10.1016/j.prevetmed.2013.10.019spa
dc.relation.referencesMaier GU, Love WJ, Karle BM, et al. Management factors associated with bovine respiratory disease in preweaned calves on California dairies: The BRD 100 study. Journal of Dairy Science. 2019;102(8):7288-7305. doi:10.3168/jds.2018-14773spa
dc.relation.referencesBayona YP, Chaux LF, Torres ID. Perfil Epidemiológico de Enfermedades Causadas por los Virus Respiratorio Sincitial Bovino (BRSV) y Parainfluenza Bovina (PI 3), en Ganadería de Dos Municipios de Sucre, Colombia. Published online June 21, 2022. Accessed July 4, 2023. https://repositorio.udes.edu.co/entities/publication/0b6c3379-f98d-475a-9f51-404917e4f308spa
dc.relation.referencesPérez J, Pinheiro D, Hanssen H. Estudio serológico de la infección por virus de parainfluenza en bovinos de Antioquia, Colombia, 1976.spa
dc.relation.referencesBetancur-Hurtado C, Castañeda-Ternera J, González-Tous M. Inmunopatología del complejo respiratorio bovino en terneros neonatos en Montería-Colombia. Revista Científica. 2017;XXVII(2):95-102.spa
dc.relation.referencesFernández MA, Bulla DM, Díaz AM, Pulido MO. Seroprevalencia y factores de riesgo del virus de parainfluenza 3 (VPI-3) en bovinos de Colombia. Revista veterinaria. 2020;31(2):155-159. doi:10.30972/vet.3124737spa
dc.relation.referencesBetancur Hurtado C, Orrego Uribe A, González Tous M. Seroepidemiological study of parainfluenza 3 virus in bovines with reproductive failure, from Monteria-Colombia. Revista de Medicina Veterinaria. 2010;(20):63-70. Accessed July 4, 2023. http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0122-93542010000200006&lng=en&nrm=iso&tlng=esspa
dc.relation.referencesBallesteros González AC, Briñez Castiblanco KG. Prevalencia y factores de riesgo asociados a complejo respiratorio en bovinos de Villavicencio, Colombia. Published online 2022. Accessed July 4, 2023. https://repository.udca.edu.co/handle/11158/4916spa
dc.relation.referencesRojas JM, Pinilla JC. Seroprevalencia del virus respiratorio sincitial bovino (VRSB) en bovinos ubicados en el municipio Valledupar, Cesar. Resultados preliminares. Rev Fac Cienc Salud UDES. 2017;4(2.S1):15. doi:10.20320/rfcsudes.v4i2.s1.r02spa
dc.relation.referencesRojas J, Pinilla J. Seroprevalencia del virus respiratorio sincitial bovino (VRSB) en bovinos ubicados en el municipio Valledupar, Cesar. Resultados preliminares | Rojas | Revista Facultad de Ciencias de la Salud UDES. Published 2017. Accessed April 29, 2021. https://www.journalhealthsciences.com/index.php/UDES/article/view/175/pdfspa
dc.relation.referencesDueñez Ruiz DA. Seroprevalencia y Factores de Riesgo Asociados a la Infección por el Virus Respiratorio Sincitial Bovino (VRSB) en Tres Municipios del Departamento Cesar, Colombia. Universidad De Santander, Facultad De Ciencias Exactas, Naturales Y Agropecuarias; 2020. https://repositorio.udes.edu.co/bitstream/001/5129/1/Seroprevalencia%20y%20factores%20de%20riesgo%20asociados%20a%20la%20infecci%C3%B3n%20por%20el%20virus%20respiratorio%20sincitial%20bovino%20%28VRSB%29%20en%20tres%20municipios%20de%20depart.pdfspa
dc.relation.referencesGálvis García T, Bautista Amorocho H, Vázquez MC. Prevalencia de anticuerpos contra diarrea viral bovina, virus sincitial bovino, rinotraqueitis infecciosa bovina, leucosis bovina, Neospora caninum, parainfluenza bovina (PI3) y paratuberculosis, en ganadería bovina de fincas ubicadas en Aguachica y Rio de Oro, Cesar. Revista Facultad de Ciencias de la Salud UDES. 2016;3(1. S1):36. doi:10.20320/rfcsudes.v3i1.s1.p022spa
dc.relation.referencesDoria-Ramos M, Oviedo-Socarras T, Oviedo-Pastrana M, et al. Seroprevalencia de agentes virales del Complejo Respiratorio Bovino en razas criollas del Centro de Investigación Turipaná de AGROSAVIA. Revista mexicana de ciencias pecuarias. 2020;11(3):771-782. doi:10.22319/rmcp.v11i3.5154spa
dc.relation.referencesBetancur H C, Rodas G J, González T M. Estudio seroepidemiológico del virus respiratorio sincitial bovino en el municipio de Montería, Colombia. Rev MVZ Córdoba. Published online September 6, 2011:2778-2784. doi:10.21897/rmvz.278spa
dc.relation.referencesVargas Bermúdez DS. Construcción de un adenovector que exprese proteínas inmunogénicas del virus de la diarrea viral bovina (BVDV). Published online 2010. Accessed July 2, 2023. https://repositorio.unal.edu.co/handle/unal/70485spa
dc.relation.referencesVillamil VV, Ramírez GC, Vera VJ, Jaime JA. Primera evidencia del Virus de Diarrea Viral Bovina (VDVB) genotipo 2 en Colombia. Rev Med Vet Zoot. 2018;65(1). doi:10.15446/rfmvz.v65n1.72020spa
dc.relation.referencesGóngora A, Villamil LC, Vera VJ, Ramírez GC, Parra JL. Diagnóstico de las principales enfermedades reproductivas en toros de la Sabana de Bogotá. Énfasis en rinotraqueitis infecciosa bovina (RIB). Revista de la Facultad de Medicina Veterinaria y de Zootecnia. 1995;43(1):37-42. Accessed July 3, 2023. https://revistas.unal.edu.co/index.php/remevez/article/view/47566spa
dc.relation.referencesNavarrete 0. J, Vera M. VJ, Ramírez G, Villamil LC. Anticuerpos monoclonales contra proteínas de la nucleocápside del virus ibr y su evaluación por elisa. Published online 2002. Accessed July 3, 2023. https://repositorio.unal.edu.co/handle/unal/40933spa
dc.relation.referencesVera A V, Betancur H C. Aislamiento del virus herpes bovino tipo 1 en bovinos del departamento de Córdoba - Colombia. Revista MVZ Córdoba. 2008;13(3):1495-1503. Accessed July 3, 2023. http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0122-02682008000300009&lng=en&nrm=iso&tlng=esspa
dc.relation.referencesPiedrahita D, Ramírez G, Vera V. Detección y caracterización por métodos moleculares de aislamientos colombianos de herpesvirus bovino tipo 1. Published online 2005. Accessed July 4, 2023. https://repositorio.unal.edu.co/handle/unal/31365spa
dc.relation.referencesZapata JC, Ossa JE, Bedoya G, Mv FNZ. Rinotraqueitis Infecciosa Bovina (RIB). Caracterización Molecular de una cepa Colombiana de Herpesvirus Bovino tipo. 2002;15.spa
dc.relation.referencesRuiz Sáenz J. Aislamiento y caracterización de cepas nativas del Herpesvirus Bovino-1 (BHV-1) para la generación de un biológico vacunal inactivado y/o recombinante. Published online 2012. Accessed July 3, 2023. https://repositorio.unal.edu.co/handle/unal/11563spa
dc.relation.referencesZambrano Trujillo LA. Seroprevalencia y factores de riesgo asociados a la exposición al Virus de la Diarrea Viral Bovina en ganaderías doble propósito en Calamar (Guaviare, Colombia). Published online March 23, 2021. Accessed July 2, 2023. https://repository.ces.edu.co/handle/10946/5215spa
dc.relation.referencesMotta Giraldo JL, Waltero García I, Abeledo MA. Prevalencia de anticuerpos al virus de la diarrea viral bovina, Herpesvirus bovino 1 y Herpesvirus bovino 4 en bovinos y búfalos en el Departamento de Caquetá, Colombia. Revista de Salud Animal. 2013;35(3):174-181. Accessed July 2, 2023. http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0253-570X2013000300005&lng=es&nrm=iso&tlng=esspa
dc.relation.referencesMoreno Figueredo G, Benavides Ortiz E, Guerrero B, Cruz Carrillo A. Asociación entre seropositividad al virus de la diarrea viral bovina, leptospira interrogans y neospora caninum, y la ocurrencia de abortos en fincas de pequeños productores del cordón lechero de Boyacá, Colombia. Revista de Investigaciones Veterinarias del Perú. 2017;28(4):1002-1009. doi:10.15381/rivep.v28i4.12850spa
dc.relation.referencesGonzález-Bautista ED, Bulla-Castañeda DM, Díaz-Anaya AM, et al. Determinación de anticuerpos antidiarrea viral bovina (DVB) en vacas lecheras de un municipio de Boyacá (Colombia). Revista de Medicina Veterinaria. 2021;(43):117-126. doi:10.19052/mv.vol1.iss43.11spa
dc.relation.referencesCarrillo AC, Figueredo GM, Medrano KG, Contreras JAM. Determinación de la presencia de anticuerpos contra Neospora caninum y el Virus de Diarrea Viral Bovina y su relación con el desempeño reproductivo de hembras bovinas del municipio de Oicatá (Boyacá). CES Medicina Veterinaria y Zootecnia. 2014;9(2):238-247. Accessed July 2, 2023. https://revistas.ces.edu.co/index.php/mvz/article/view/3180spa
dc.relation.referencesGuerrero LFN, Colorado NR, Araque JM, Guerrero LFN, Colorado NR, Araque JM. Prevalencia de diarrea viral bovina, neosporosis bovina, leucosis bovina enzoótica y paratuberculosis bovina en vacas de doble propósito en condiciones del trópico colombiano. Revista de Investigaciones Veterinarias del Perú. 2022;33(2). doi:10.15381/rivep.v33i2.20694spa
dc.relation.referencesBetancur H, Gogorza LM, Martinez FG. Seroepidemiología de la diarrea viral bovina en Montería (Córdoba, Colombia). Seroepidemiology of the bovine viral diarrhea in the municipality of Montería-Córdoba-Colombia. 2007;27, no. 2. Accessed July 2, 2023. http://sedici.unlp.edu.ar/handle/10915/11204spa
dc.relation.referencesParra L, Vera A V, Villamil LC, Ramirez G. Seroepidemiologia de la Diarrea Viral Bovina en explotaciones lecheras de la Saban de Bogotá. Revista de la Facultad de Medicina Veterinaria y de Zootecnia. 1994;42(1):29-44. Accessed July 2, 2023. https://revistas.unal.edu.co/index.php/remevez/article/view/48064spa
dc.relation.referencesBuitrago Horta ER. Determinación de la prevalencia de animales persistentemente infectados con el virus de diarrea viral bovina (DVB) y factores de riesgo asociados con la exposición al virus en terneras de hatos lecheros de la Sabana de Bogotá. Published online 2015. Accessed July 3, 2023. https://repositorio.unal.edu.co/handle/unal/55348spa
dc.relation.referencesCifuentes Sánchez LY, Hurtado Ibáñez LA. Factores asociados a la presentación de Diarrea Viral Bovina (VDVB) en hatos bovinos del municipio de Tauramena, Casanare 2015. Published online November 2019. Accessed July 2, 2023. https://repositorio.unicolmayor.edu.co/handle/unicolmayor/271spa
dc.relation.referencesRivera DC, Rincón JC, Echeverry JC. Prevalencia de algunas enfermedades infecciosas en bovinos de resguardos indígenas del Cauca, Colombia, 2017. Rev UDCA Act & Div Cient. 2018;21(2). doi:10.31910/rudca.v21.n2.2018.983spa
dc.relation.referencesPuertas Revelo YA. Análisis de la seroprevalencia del virus de diarrea viral bovina y rinotraqueitis infecciosa bovina del municipio de Guachucal (Nariño) muestreados dentro del “proyecto piloto de excelencia sanitaria en ganadería de leche” realizado por vecol entre junio-agosto del año 2014. Published 2017. Accessed July 2, 2023. https://biblioteca.udenar.edu.co/atenea/91525.pdfspa
dc.relation.referencesCedeño Quevedo D, Benavides Benavides B, Cárdenas G, Herrera C. Seroprevalence and risk factors associated to BHV-1 and DVBV in dairy herds in Pasto, Colombia, in 2011. Revista Lasallista de Investigación. 2011;8(2):61-68. Accessed July 3, 2023. http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S1794-44492011000200007&lng=en&nrm=iso&tlng=esspa
dc.relation.referencesNavas Suárez P. Determinación de anticuerpos anti-diarrea viral bovina DVB mediante Elisa competitivo en una población cautiva de venados cola blanca Odocoileus virginianus en Cundinamarca, Colombia. Medicina Veterinaria. Published online January 1, 2013. https://ciencia.lasalle.edu.co/medicina_veterinaria/18spa
dc.relation.referencesMotta Giraldo JL, Waltero García I, Abeledo MA, Fernández O. Estudio retrospectivo de agentes infecciosos que afectan la reproducción bovina en el departamento del Caquetá, Colombia. Revista de Salud Animal. 2012;34(3):159-164. Accessed July 2, 2023. http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0253-570X2012000300004&lng=es&nrm=iso&tlng=enspa
dc.relation.referencesVargas-Niño A, R JV, Parra-Martin JA, R MCV, O AG, Mogollón-Waltero EM. Estado serológico para IBR, DVB, Leucosis, Leptospira y Neospora caninum en hembras bovinas del Departamento de Santander, Colombia. Revista MVZ Córdoba. 2018;23(2):6671-6680. doi:10.21897/rmvz.1341spa
dc.relation.referencesRuiz-Sáenz J, Jaime J, Vera VJ. Prevalencia serológica y aislamiento del Herpesvirus Bovino-1 (BHV-1) en hatos ganaderos de Antioquia y del Valle del Cauca. Revista Colombiana de Ciencias Pecuarias. 2010;23(3):299-307. Accessed July 3, 2023. http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-06902010000300005&lng=en&nrm=iso&tlng=esspa
dc.relation.referencesVargas D, Bohórquez A, Parra J, Jaime J, Góngora A. Evaluacion serologica de herpesvirus bovino 1 y 5 en sistemas de cria en la Altillanura Colombiana. Revista MVZ (Medicina Veterinaria y Zootecnia). 2016;21(2):5381-5390.spa
dc.relation.referencesLancheros-Buitrago DJ, Bulla-Castañeda DM, Pulido-Medellin MO, López Buitrago HA, Díaz-Anaya AM, Garcia-Corredor DJ. Serodiagnosis and Risk Factors Associated with Infectious Agents of Reproductive Diseases in Bovines of Chiquinquirá, District of Boyacá (Colombia). Veterinary Medicine International. 2022;2022:e7436651. doi:10.1155/2022/7436651spa
dc.relation.referencesOrtiz-González AD, Buitrago HAL, Bulla-Castañeda DM, et al. Seroprevalence and risk factors associated with bovine herpesvirus 1 in dairy herds of Colombia. Vet World. 2022;15(6):1550-1556. doi:10.14202/vetworld.2022.1550-1556spa
dc.relation.referencesFlórez LMM, Echeverry OAC, Ordóñez FJP. Estudio seroepidemiológico del Herpesvirus Bovino 1 (BoHV-1) en ganado destinado al sacrificio en la región del Magdalena Medio colombiano. Revista Veterinaria y Zootecnia (On Line). 2011;5(2):82-87.spa
dc.relation.referencesBetancur H C, González T M, Reza G. L. Seroepidemiología de la Rinotraqueitis Infecciosa Bovina en el municipio de Montería, Colombia. Revista MVZ Córdoba. 2006;11(2):830-836. Accessed July 3, 2023. http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0122-02682006000200008&lng=en&nrm=iso&tlng=esspa
dc.relation.referencesPiedrahita LE, Montoya LM, Pedraza FJ. Herpes Virus Bovino tipo 1 (BoHV-1) como posible causa de encefalitis en bovinos de la región del Magdalena Medio Colombiano: Estudio serológico y análisis epidemiológico. Revista Colombiana de Ciencias Pecuarias. 2010;23(2):191-198. Accessed July 3, 2023. http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-06902010000200008&lng=en&nrm=iso&tlng=esspa
dc.relation.referencesAytogu G, Toker EB, Kadiroglu B, Ates O, Goktuna PT. First Isolation And Characterization Of Bovine Herpesvirus 1.2b (BoHV-1.2b ) Strain From Upper Respiratory Tract Of Cattle In Türkiye. Published online 2022.spa
dc.relation.referencesCooper VL, Brodersen BW. Respiratory Disease Diagnostics of Cattle. Veterinary Clinics of North America: Food Animal Practice. 2010;26(2):409-416. doi:10.1016/j.cvfa.2010.04.009spa
dc.relation.referencesAngen Ø, Thomsen J, Larsen LE, et al. Respiratory disease in calves: Microbiological investigations on trans-tracheally aspirated bronchoalveolar fluid and acute phase protein response. Veterinary Microbiology. 2009;137(1-2):165-171. doi:10.1016/j.vetmic.2008.12.024spa
dc.relation.referencesGodinho KS, Sarasola P, Renoult E, et al. Use of deep nasopharyngeal swabs as a predictive diagnostic method for natural respiratory infections in calves. Vet Rec. 2007;160(1):22-25. doi:10.1136/vr.160.1.22spa
dc.relation.referencesCaswell JL, Hewson J, Slavić Ð, DeLay J, Bateman K. Laboratory and Postmortem Diagnosis of Bovine Respiratory Disease. Veterinary Clinics of North America: Food Animal Practice. 2012;28(3):419-441. doi:10.1016/j.cvfa.2012.07.004spa
dc.relation.referencesPowell JG, Richeson JT, Kegley EB, et al. Immunologic, health, and growth responses of beef calves administered pentavalent modified-live virus respiratory vaccine in the presence of maternal antibody versus a traditional vaccination regimen | The Bovine Practitioner. Published online December 18, 2019. Accessed July 5, 2023. https://bovine-ojs-tamu.tdl.org/bovine/article/view/2807spa
dc.relation.referencesZhang M, Hill JE, Godson DL, Ngeleka M, Fernando C, Huang Y. The pulmonary virome, bacteriological and histopathological findings in bovine respiratory disease from western Canada. Transbound Emerg Dis. 2020;67(2):924-934. doi:10.1111/tbed.13419 195. Caswell JL, Williams KJ. Respiratory system. In: Jubb, Kennedy & Palmer’s Pathology of Domestic Animals: Volume 2. Elsevier; 2016:465-591.e4. doi:10.1016/B978-0-7020-5318-4.00011-5spa
dc.relation.referencesTheurer ME, Larson RL, White BJ. Systematic review and meta-analysis of the effectiveness of commercially available vaccines against bovine herpesvirus, bovine viral diarrhea virus, bovine respiratory syncytial virus, and parainfluenza type 3 virus for mitigation of bovine respiratory disease complex in cattle. J Am Vet Med Assoc. 2015;246(1):126-142. doi:10.2460/javma.246.1.126spa
dc.relation.referencesKleiboeker SB, Lee SM, Jones CA, Estes DM. Evaluation of shedding of bovine herpesvirus 1, bovine viral diarrhea virus 1, and bovine viral diarrhea virus 2 after vaccination of calves with a multivalent modified-live virus vaccine. Journal of the American Veterinary Medical Association. 2003;222(10):1399-1403. doi:10.2460/javma.2003.222.1399spa
dc.relation.referencesChamorro MF, Palomares RA. Bovine Respiratory Disease Vaccination Against Viral Pathogens. Veterinary Clinics of North America: Food Animal Practice. 2020;36(2):461-472. doi:10.1016/j.cvfa.2020.03.006spa
dc.relation.referencesVan Oirschot JT. Diva vaccines that reduce virus transmission. Journal of Biotechnology. 1999;73(2-3):195-205. doi:10.1016/S0168-1656(99)00121-2spa
dc.relation.referencesSvensson C, Hultgren J, Oltenacu PA. Morbidity in 3–7-month-old dairy calves in south-western Sweden, and risk factors for diarrhoea and respiratory disease. Preventive Veterinary Medicine. 2006;74(2):162-179. doi:10.1016/j.prevetmed.2005.11.008spa
dc.relation.referencesSvensson C, Hultgren J, Oltenacu PA. Morbidity in 3–7-month-old dairy calves in south-western Sweden, and risk factors for diarrhoea and respiratory disease. Preventive Veterinary Medicine. 2006;74(2):162-179. doi:10.1016/j.prevetmed.2005.11.008spa
dc.relation.referencesHoppe IBAL, Medeiros ASR de, Arns CW, Samara SI. Bovine respiratory syncytial virus seroprevalence and risk factors in non-vaccinated dairy cattle herds in Brazil. BMC Vet Res. 2018;14(1):208. doi:10.1186/s12917-018-1535-8spa
dc.relation.referencesRoche Diagnostics GmbH RAS. High Pure Viral Nucleic Acid Kit. High Pure Viral Nucleic Acid Kit Rapidly isolate highly purified viral DNA and RNA. https://lifescience.roche.com/documents/High-Pure-Viral-Nucleic-Acid-Kit.pdfspa
dc.relation.referencesRoche Diagnostics GmbH RAS. High Pure Viral Nucleic Acid Kit. High Pure Viral Nucleic Acid Kit Rapidly isolate highly purified viral DNA and RNA. https://lifescience.roche.com/documents/High-Pure-Viral-Nucleic-Acid-Kit.pdfspa
dc.relation.referencesHigh-Capacity RNA-to-cDNATM Kit. Accessed March 28, 2023. https://www.thermofisher.com/order/catalog/product/4387406spa
dc.relation.referencesZhang M, Hill JE, Godson DL, Ngeleka M, Fernando C, Huang Y. The pulmonary virome, bacteriological and histopathological findings in bovine respiratory disease from western Canada. Transbound Emerg Dis. 2020;67(2):924-934. doi:10.1111/tbed.13419spa
dc.relation.referencesRidpath JF, Fulton RW, Bauermann FV, Falkenberg SM, Welch J, Confer AW. Sequential exposure to bovine viral diarrhea virus and bovine coronavirus results in increased respiratory disease lesions: clinical, immunologic, pathologic, and immunohistochemical findings. J VET Diagn Invest. 2020;32(4):513-526. doi:10.1177/1040638720918561spa
dc.relation.referencesOliveira VHS, Dall Agnol AM, Fritzen JTT, Lorenzetti E, Alfieri AA, Alfieri AF. Microbial diversity involved in the etiology of a bovine respiratory disease outbreak in a dairy calf rearing unit. Comparative Immunology, Microbiology and Infectious Diseases. 2020;71:101494. doi:10.1016/j.cimid.2020.101494spa
dc.relation.referencesFulton RW, Neill JD, Saliki JT, Landis C, Burge LJ, Payton ME. Genomic and antigenic characterization of bovine parainfluenza-3 viruses in the United States including modified live virus vaccine (MLV) strains and field strains from cattle. Virus Res. 2017;235:77-81. doi:10.1016/j.virusres.2017.04.009spa
dc.relation.referencesMars MH, Bruschke CJ, van Oirschot JT. Airborne transmission of BHV1, BRSV, and BVDV among cattle is possible under experimental conditions. Vet Microbiol. 1999;66(3):197-207. doi:10.1016/s0378-1135(99)00009-7spa
dc.relation.referencesFulton RW, Briggs RE, Payton ME, et al. Maternally derived humoral immunity to bovine viral diarrhea virus (BVDV) 1a, BVDV1b, BVDV2, bovine herpesvirus-1, parainfluenza-3 virus bovine respiratory syncytial virus, Mannheimia haemolytica and Pasteurella multocida in beef calves, antibody decline by half-life studies and effect on response to vaccination. Vaccine. 2004;22(5-6):643-649. doi:10.1016/j.vaccine.2003.08.033spa
dc.relation.referencesPlatt R, Widel PW, Kesl LD, Roth JA. Comparison of humoral and cellular immune responses to a pentavalent modified live virus vaccine in three age groups of calves with maternal antibodies, before and after BVDV type 2 challenge. Vaccine. 2009;27(33):4508-4519. doi:10.1016/j.vaccine.2009.05.012spa
dc.relation.referencesLovato L, Inman M, Henderson G, Doster A, Jones C. Infection of Cattle with a Bovine Herpesvirus 1 Strain That Contains a Mutation in the Latency-Related Gene Leads to Increased Apoptosis in Trigeminal Ganglia during the Transition from Acute Infection to Latency. Journal of Virology. 2003;77(8):4848-4857. doi:10.1128/JVI.77.8.4848-4857.2003spa
dc.relation.referencesDias JA, Alfieri AA, Ferreira-Neto JS, Gonçalves VSP, Muller EE. Seroprevalence and risk factors of bovine herpesvirus 1 infection in cattle herds in the state of Paraná, Brazil. Transbound Emerg Dis. 2013;60(1):39-47. doi:10.1111/j.1865-1682.2012.01316.xspa
dc.relation.referencesWest K, Bogdan J, Hamel A, et al. A comparison of diagnostic methods for the detection of bovine respiratory syncytial virus in experimental clinical specimens. Can J Vet Res. 1998;62(4):245-250. Accessed August 1, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189489/spa
dc.relation.referencesKumagai A, Kanno T, Kawauchi K, Tanaka K, Ishihara R, Hatama S. Phylogenetic and antigenic analysis of bovine parainfluenza virus type 3 isolated in Japan between 2002 and 2019. Veterinary Microbiology. 2020;247:108774. doi:10.1016/j.vetmic.2020.108774spa
dc.relation.referencesRen Y, Tang C, Yue H. Prevalence and Molecular Characterization of Bovine Parainfluenza Virus Type 3 in Cattle Herds in China. Animals (Basel). 2023;13(5):793. doi:10.3390/ani13050793spa
dc.relation.referencesWang X, Hu J, Meng F, et al. Isolation, Identification, and Genetic Phylogenetic Analysis of Two Different Genotypes of Bovine Parainfluenza 3 Virus in China. Viruses. 2022;14(10):2221. doi:10.3390/v14102221spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacionalspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.subject.agrovocEnfermedades de los animalesspa
dc.subject.agrovocanimal diseaseseng
dc.subject.agrovocRebaño de lechespa
dc.subject.agrovocdairy herdseng
dc.subject.agrovocEnfermedades respiratoriasspa
dc.subject.agrovocrespiratory diseaseseng
dc.subject.ddc630 - Agricultura y tecnologías relacionadas::636 - Producción animalspa
dc.subject.proposalEnfermedad respiratoria bovinaspa
dc.subject.proposalEnfermedad respiratoria de los ternerosspa
dc.subject.proposalEnfermedades respiratoriasspa
dc.subject.proposalBRSVspa
dc.subject.proposalBPIV3spa
dc.subject.proposalBoHV-1spa
dc.subject.proposalBVDVspa
dc.subject.proposalBovine respiratory diseaseeng
dc.subject.proposalRespiratory disease of calveseng
dc.subject.proposalRespiratory diseaseseng
dc.subject.proposalBRSVeng
dc.subject.proposalBPIV3eng
dc.subject.proposalBoHV-1eng
dc.subject.proposalBVDVeng
dc.titleDetección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecherosspa
dc.title.translatedDetection of viruses associated with respiratory disease in calves from dairy herdseng
dc.typeTrabajo de grado - Maestríaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/masterThesisspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TMspa
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
dcterms.audience.professionaldevelopmentInvestigadoresspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa

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