Características clínicas de pacientes con anemia hemolítica autoinmune en hospitales de Bogotá
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Velásquez Quintero, Germán Andrés
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Trabajo de grado - Pregrado
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EspañolFecha de publicación
2015
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La AHAI es una enfermedad sobre la cual se desconocen muchos aspectos. No tenemos conocimiento de algún trabajo acerca de esta patología en nuestro país. Nuestro objetivo es describir las características clínicas, los resultados del tratamiento y las complicaciones asociadas a esta patología en pacientes atendidos en hospitales de Bogotá. Las características demográficas de los pacientes son similares a lo reportado en la literatura. Se encontró que la severidad de la anemia fue menor a lo reportado por otros autores . La terapia más usada como primera línea son los corticoides. Como terapia de segunda línea la terapia más usada fue la azatioprina .La mitad de los pacientes tuvieron una AHAI secundaria siendo las causas más comunes las enfermedades autoinmunes seguido de los síndromes linfoproliferativos. Se encontró una prevalencia más baja de trombosis que lo reportado en otras publicaciones
Abstract. Many characteristics about autoimmune hemolytic are unknown. To our best knowledge there are no studies about this disease in our country. Our aim is to describe clinical and laboratory characteristics , treatment results and complications associated with this disease in patients who were seen in Bogota hospitals . The demographics characteristics are similar to other studies reported in the literature . The anemia was less profound than previously reported in other studies. Most commonly used drug treatment were corticosteroids. As a second-line therapy azathioprine was the most frecuently used drug . Half of the patients had a secondary autoimmune hemolytic anemia and the most commonly secundary causes were connective tissue disorders followed by lymphoproliferative disorders . The thrombosis prevalence was lower than in previously reported studies
Abstract. Many characteristics about autoimmune hemolytic are unknown. To our best knowledge there are no studies about this disease in our country. Our aim is to describe clinical and laboratory characteristics , treatment results and complications associated with this disease in patients who were seen in Bogota hospitals . The demographics characteristics are similar to other studies reported in the literature . The anemia was less profound than previously reported in other studies. Most commonly used drug treatment were corticosteroids. As a second-line therapy azathioprine was the most frecuently used drug . Half of the patients had a secondary autoimmune hemolytic anemia and the most commonly secundary causes were connective tissue disorders followed by lymphoproliferative disorders . The thrombosis prevalence was lower than in previously reported studies