El habla de personas con enfermedad de Parkinson tras una neurocirugía: seguimiento de pacientes hispanohablantes en Bogotá durante un año

dc.contributor.advisorCamargo Mendoza, Maryluz
dc.contributor.advisorBernal Pacheco, Oscar
dc.contributor.authorCastillo Triana, Nicolás
dc.contributor.orcid0000-0003-0770-293Xspa
dc.contributor.researchgroupVoz, Habla y Degluciónspa
dc.contributor.scopus57196298692spa
dc.date.accessioned2022-11-28T22:16:36Z
dc.date.available2022-11-28T22:16:36Z
dc.date.issued2022
dc.descriptionilustraciones, gráficasspa
dc.description.abstractSe describieron las características del habla de un grupo de hispanohablantes con enfermedad de Parkinson (EP) que fueron tratados con estimulación cerebral profunda del núcleo subtalámico (STN-DBS). Se efectuó un estudio longitudinal con medidas PRE y POST implantación de la STN-DBS en 9 participantes con EP idiopática (4 mujeres y 5 hombres). Por cada participante se evaluó el deterioro del habla al inicio y al final del seguimiento y se tomaron medidas acústicas de la voz (f0, SDf0, intensidad, Jitter, RAP, Shimmer, NHR, HNR, LTAS y CPPs), tiempo máximo de fonación (TMF), de inteligibilidad del habla (% de palabras correctamente identificadas y grado de inteligibilidad), de velocidad del habla y de diadococinesia oral, antes de recibir la STN-DBS y cada 3 meses post intervención durante 1 año. Aunque no se encontraron cambios grupales POST que fueran estadísticamente significativos en ninguno de los parámetros de habla estudiados, ni un patrón de cambio identificable a lo largo del tiempo, un análisis de frecuencia de cambios POST intervención, así como de cambios individuales sostenidos en dos o más momentos de seguimiento POST constató cómo el efecto de la STN-DBS no fue el mismo para el habla de todos los participantes. Los datos muestran que estas diferencias podrían radicar en el sexo, el nivel de disartria PRE intervención, el estado de la medicación y los niveles de ciertos parámetros de estimulación cerebral, pues relacionadas con todas estas variables se evidenciaron cambios en el habla. Este es el primer estudio de su tipo en hispanohablantes y sus hallazgos garantizan investigación futura. (Texto tomado de la fuente)spa
dc.description.abstractThe aim of this study was to describe the speech characteristics of a sample of Spanish-speaking Parkinson´s disease (PD) patients treated with Subthalamic Nucleus Deep Brain Stimulation (STN-DBS). A follow-up study of PRE and POST treatment onset speech measures was carried out on nine idiopathic PD patients who underwent STN-DBS surgery (4 females and 5 males). The severity of dysarthria of every patient was assessed at the beginning and the end of the follow-up, acoustic measures of voice (fo, SDfo, intensity, Jitter, RAP, Shimmer, NHR, HNR, LTAS y CPPs), Maximum Phonation Time (MPT), measures of intelligibility of speech (grade of intelligibility and percentage of correctly identified words), speech rate, and oral diadochokinesia were calculated before surgery and every 3 months post-surgery during one year. Although statistical significative post-surgery group changes in any speech measure, or a recognizable pattern of speech change during follow-up were not found, an analysis of frequency of POST surgery and of sustained POST surgery changes revealed that STN-DBS influences speech in a different way depending on the speech measure, sex, medication status, pre-surgery level of dysarthria and stimulation parameters levels, all of which were found related with speech parameters variations in some way. Currently, all of the research in this field is from non-Spanish-speaking PD patients an all of the findings of this study warrant further research.eng
dc.description.degreelevelMaestríaspa
dc.description.degreenameMagíster en Neurocienciasspa
dc.description.methodsSeguimiento longitudinal; serie de casos.spa
dc.format.extent288 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameUniversidad Nacional de Colombiaspa
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombiaspa
dc.identifier.repourlhttps://repositorio.unal.edu.co/spa
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/82815
dc.language.isospaspa
dc.publisherUniversidad Nacional de Colombiaspa
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotáspa
dc.publisher.facultyFacultad de Medicinaspa
dc.publisher.placeBogotá, Colombiaspa
dc.publisher.programBogotá - Medicina - Maestría en Neurocienciasspa
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.licenseAtribución-NoComercial 4.0 Internacionalspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/spa
dc.subject.ddc610 - Medicina y saludspa
dc.subject.ddc410 - Lingüísticaspa
dc.subject.lembNeurocirugíaspa
dc.subject.lembNeurosurgeryeng
dc.subject.lembEnfermedades cerebralesspa
dc.subject.lembBrain - Diseaseseng
dc.subject.proposalParkinson´s diseaseeng
dc.subject.proposaldeep brain stimulationeng
dc.subject.proposaldysarthriaeng
dc.subject.proposalvoiceeng
dc.subject.proposalenfermedad de Parkinsonspa
dc.subject.proposalestimulación cerebral profundaspa
dc.subject.proposaldisartriaspa
dc.subject.proposalvozspa
dc.titleEl habla de personas con enfermedad de Parkinson tras una neurocirugía: seguimiento de pacientes hispanohablantes en Bogotá durante un añospa
dc.title.translatedSpeech outcome of people with Parkinson´s disease after a neurosurgery: one-year follow-up of Spanish-speaking patients in Bogotáeng
dc.typeTrabajo de grado - Maestríaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
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dc.type.driverinfo:eu-repo/semantics/masterThesisspa
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dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
dcterms.audience.professionaldevelopmentEstudiantesspa
dcterms.audience.professionaldevelopmentInvestigadoresspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa

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