Expresión de receptores para la hormona luteinizante y su ácido ribonucléico mensajero en folículos preovulatorios de vacas Romosinuano y Brahman - posible relación con los niveles séricos de progesterona
| dc.contributor.advisor | Hernández Vásquez, Aureliano | spa |
| dc.contributor.author | Vejarano Orjuela, Álvaro | spa |
| dc.contributor.researchgroup | Biología de la adaptación animal al trópico - Genética y Biotecnología de la reproducción . | spa |
| dc.date.accessioned | 2020-08-04T00:51:06Z | spa |
| dc.date.available | 2020-08-04T00:51:06Z | spa |
| dc.date.issued | 2019-06-23 | spa |
| dc.description.abstract | In order to identify and compare possible polymorphisms of the Luteinizing hormone receptor (LHR/LHCGR), the preovulatory follicle development (POF), the corpus luteum (CL) development and its progesterone (P4) secretion, as potential indicators of fertility in Romosinuano (RS) and Brahman (Br) breeds, an echographic follow up of ovarian dynamics during two consecutive estrous cycles (EC) was carried out in five females of each breed and their ovaries that contained the POF were surgically obtained. The POF was sectioned through its major diameter, as to obtain, from one half, histological preparations of 5 µm thick to calculate the volume occupied by the granulosa (GCV) and inner theca cells (ITCV). From the other half of the POF the total mRNA was extracted and the cDNA obtained as related to the gen that codifies for the LHCGR for sequential study in Macrogen. No differences were found (p>0.05) between the two breeds for the inter-estrous period, estrous duration, estrous – ovulation interval, the POF´s diameter, the GCV or TICV. Differences were encountered between breeds for the CL´s Diameter and the (P4) values at the seventh day of the estrous cycle. There was no correlation between corpus luteum diameter and (P4). The codding region of the LHCGR gen did not register variants related to the Gen Bank´s report in any of the 2 breeds studied. It is recommended to extend the present study to other physiological events, such as postpartum, by measuring the expression of the LHCGR gene and steroidogenesis in the same cell layers. | spa |
| dc.description.abstract | Para identificar y comparar posibles polimorfismos del gen del receptor de la hormona luteinizante (LHCGR), el desarrollo del folículo preovulatorio (FPO), el consecuente desarrollo del cuerpo lúteo (CL) y su secreción de progesterona (P4) como potenciales indicadores de fertilidad en bovinos Romosinuano (RS) y Brahman (Br), se realizó a cinco hembras de cada raza seguimiento ecográfico de la dinámica ovárica durante dos ciclos estrales consecutivos (CE); se obtuvieron quirúrgicamente los ovarios que contenían el FPO y este se seccionó diametralmente para obtener de una de las mitades preparados histológicos de 5 µm de grosor para calcular el volumen ocupado por la capa de células de la granulosa (VCG) y de la teca interna (VCTI). De la pared de la otra mitad del FPO se extrajo el ARNm total y se obtuvo el ADNc para el gen que codifica el LHCGR para secuenciación en Macrogen. No se encontraron diferencias significativas (p>0.05) entre las dos razas para periodo inter estros, duración del estro, intervalo estro – ovulación, el diámetro del FPO, ni para el VCG o VTI. No hubo correlación entre las variables Diámetro FPO y VCG o VCTI. Se hallaron diferencias en el diámetro del CL y (P4) en el día siete del CE. No se observó correlación entre DCL y (P4). La región codificante del gen LHCGR no registró variantes con respecto a los reportes del Gen Bank. Se recomienda ampliar el estudio a otros estados fisiológicos como el posparto, midiendo la expresión del gen del LHCGR y la esteroidogénesis en las mismas capas celulares. | spa |
| dc.description.additional | Línea de Investigación: Fisiología del Ciclo Estral y Mortalidad Embrionaria. | spa |
| dc.description.comments | avejaran@ut.edu.co | spa |
| dc.description.degreelevel | Doctorado | spa |
| dc.format.extent | 98 | spa |
| dc.format.mimetype | application/pdf | spa |
| dc.identifier.citation | Vejarano, O.A. | spa |
| dc.identifier.uri | https://repositorio.unal.edu.co/handle/unal/77910 | |
| dc.language.iso | spa | spa |
| dc.publisher.branch | Universidad Nacional de Colombia - Sede Bogotá | spa |
| dc.publisher.program | Bogotá - Medicina Veterinaria y de Zootecnia - Doctorado en Ciencias - Salud Animal o Producción Animal | spa |
| dc.relation.references | Chazal, G., Faudon, M., Gogan, F., & Laplante, E. (1974). Negative and positive effects of oestradiol upon luteinizing hormone secretion in the female rat. Journal of Endocrinology, 61(3), 511-512. | spa |
| dc.relation.references | Choi, Y., Yuan, D., & Rajkovic, A. (2008). Germ cell-specific transcriptional regulator sohlh2 is essential for early mouse folliculogenesis and oocyte-specific gene expression. Biology of Reproduction, 79(6), 1176-1182. | spa |
| dc.relation.references | Clelland, E., & Peng, C. (2009). Endocrine/paracrine control of zebrafish ovarian development. Molecular and Cellular Endocrinology, 312(1-2), 42-52. | spa |
| dc.relation.references | Combelles, C. M. (2013). The antral follicle: a microenvironment for oocyte differentiation. International Journal of Developmental Biology, 56(10-11-12), 819-831. | spa |
| dc.relation.references | Comin, A., Peric, T., Montillo, M., Cappa, A., Marchi, V., Veronesi, M. C., & Prandi, A. (2017). Luteal activity and effect of dietary energy restriction on follicular development in lactating cows. Reproduction in Domestic Animals. | spa |
| dc.relation.references | Cooke, R., & Arthington, J. (2009). Plasma progesterone concentrations as puberty criteria for Brahman-crossbred heifers. Livestock Science, 123(1), 101-105. | spa |
| dc.relation.references | Custer, E., Berardinelli, J., Short, R., Wehrman, M., & Adair, R. (1990). Postpartum interval to estrus and patterns of LH and progesterone in first-calf suckled beef cows exposed to mature bulls. Journal of animal science, 68(5), 1370-1377. | spa |
| dc.relation.references | Delemi, A. Identificaion of the expression level to LH-r Gene in dominant and cystic ovarian follicles cells of the cow. | spa |
| dc.relation.references | Delidow, B., Lynch, J., White, B., & Peluso, J. (1992). Regulation of proto-oncogene expression and deoxyribonucleic acid synthesis in granulosa cells of perifused immature rat ovaries. Biology of Reproduction, 47(3), 428-435. | spa |
| dc.relation.references | Di Rienzo, J., Casanoves, F., Balzarini, M., Gonzalez, L., Tablada, M., & Robledo, C. I. (2008). versión 2008. Córdoba (Argentina): Grupo InfoStat, FCA, Universidad Nacional de Córdoba. | spa |
| dc.relation.references | Dickinson, R. E., Stewart, A. J., Myers, M., Millar, R. P., & Duncan, W. C. (2009). Differential expression and functional characterization of luteinizing hormone receptor splice variants in human luteal cells: implications for luteolysis. Endocrinology, 150(6), 2873-2881. | spa |
| dc.relation.references | Donaldson, L., Bassett, J., & Thorburn, G. (1970). Peripheral plasma progesterone concentration of cows during puberty, oestrous cycles, pregnancy and lactation, and the effects of under-nutrition or exogenous oxytocin on progesterone concentration. Journal of Endocrinology, 48(4), 599-614. | spa |
| dc.relation.references | Dubey, P. K., & Sharma, G. T. (2016). Nitric oxide and ovarian folliculogenesis: a possible role in follicular atresia. Asian-Australasian Journal of Animal Sciences. | spa |
| dc.relation.references | Dufau, M. L., Tsai-Morris, C. H., Zhang, Z. H., & Buczko, E. (1995). Structure and regulation of the luteinizing hormone receptor gene. The Journal of steroid biochemistry and molecular biology, 53(1), 283-291. | spa |
| dc.relation.references | Durlinger, A. L., Gruijters, M. J., Kramer, P., Karels, B., Ingraham, H. A., Nachtigal, M. W., . . . Themmen, A. P. (2002). Anti-Mullerian hormone inhibits initiation of primordial follicle growth in the mouse ovary. Endocrinology, 143(3), 1076-1084. | spa |
| dc.relation.references | Edson, M. A., Nagaraja, A. K., & Matzuk, M. M. (2009). The mammalian ovary from genesis to revelation. Endocrine reviews, 30(6), 624-712. | spa |
| dc.relation.references | Enjoy, D., Endel, D., Cabrera, P., Vivas, I., & Díaz, T. (2012). Dinámica folicular ovárica durante el ciclo estral en vacas brahman. Revista de la Facultad de Ciencias Veterinarias, 53(1), 39-47. | spa |
| dc.relation.references | Eppig, J. J., Wigglesworth, K., & Chesnel, F. (1993). Secretion of cumulus expansion enabling factor by mouse oocytes: relationship to oocyte growth and competence to resume meiosis. Developmental biology, 158(2), 400-409. | spa |
| dc.relation.references | Espey, L. L. (1980). Ovulation as an inflammatory reaction-a hypothesis. Biology of Reproduction, 22(1), 73-106. | spa |
| dc.relation.references | Figueiredo, R., Barros, C., Pinheiro, O., & Soler, J. (1997). Ovarian follicular dynamics in Nelore breed (Bos indicus) cattle. Theriogenology, 47(8), 1489-1505. | spa |
| dc.relation.references | Forde, N., Beltman, M., Lonergan, P., Diskin, M., Roche, J., & Crowe, M. (2011). Oestrous cycles in Bos taurus cattle. Animal reproduction science, 124(3), 163-169. | spa |
| dc.relation.references | Forrest, D., Kaltenbach, C., & Dunn, T. (1981). Estriol-and estradiol-17 beta-induced luteinizing hormone release in ovariectomized cows and ewes. Journal of animal science, 52(5), 1106-1113. | spa |
| dc.relation.references | Fortune, J., Willis, E., Bridges, P., & Yang, C. (2009). The periovulatory period in cattle: progesterone, prostaglandins, oxytocin and ADAMTS proteases. Animal reproduction/Colegio Brasileiro de Reproducao Animal, 6(1), 60. | spa |
| dc.relation.references | Fricke, P. (2002). Scanning the future—Ultrasonography as a reproductive management tool for dairy cattle. Journal of dairy science, 85(8), 1918-1926. | spa |
| dc.relation.references | Galina, C., & Arthur, G. (1990). Review on cattle reproduction in the tropics. Part 4. Oestrous cycles. Paper presented at the Animal Breeding Abstracts. | spa |
| dc.relation.references | García-Guerra, A., Kirkpatrick, B. W., & Wiltbank, M. C. (2017). Follicular waves and hormonal profiles during the estrous cycle of carriers and non-carriers of the Trio allele, a major bovine gene for high ovulation and fecundity. Theriogenology. | spa |
| dc.relation.references | Gay, V., Midgley Jr, A., & Niswender, G. (1970). Patterns of gonadotrophin secretion associated with ovulation. Paper presented at the Federation proceedings. | spa |
| dc.relation.references | Gilbert, I. (2011). Étude de l'expression génique dans les cellules de la granulosa bovine durant la période pré-ovulatoire. | spa |
| dc.relation.references | Ginther, O. (2000). Selection of the dominant follicle in cattle and horses. Animal reproduction science, 60, 61-79. | spa |
| dc.relation.references | Ginther, O., Bergfelt, D., Beg, M., & Kot, K. (2001). Follicle Selection in Cattle: Role of Luteinizing Hormone 1. Biology of Reproduction, 64(1), 197-205. | spa |
| dc.relation.references | Ginther, O., Bergfelt, D., Kulick, L., & Kot, K. (1998). Pulsatility of systemic FSH and LH concentrations during follicular-wave development in cattle. Theriogenology, 50(4), 507-519. | spa |
| dc.relation.references | Ginther, O., Wiltbank, M., Fricke, P., Gibbons, J., & Kot, K. (1996). Selection of the dominant follicle in cattle. Biology of Reproduction, 55, 1187-1194. | spa |
| dc.relation.references | Góngora, A., & Hernández, A. (2006). Comportamiento sexual, duración del estro y del ciclo estral en novillas criollas sanmartineras y brahman del piedemonte llanero colombiano. Livestock Research for Rural Development, 18(1). | spa |
| dc.relation.references | Góngora, A., & Hernández, A. (2010). La reproducción de la vaca se afecta por las altas temperaturas ambientales. Revista UDCA Actualidad & Divulgación Científica, 13(2), 141-151. | spa |
| dc.relation.references | GonzaIez-Padilla, E., Wiltbank, J., & Niswender, G. (1975). Puberty in beef heifers. I. The interrelationship between pituitary, hypothalamic and ovarian hormones. Journal of animal science, 40(6), 1091-1104. | spa |
| dc.relation.references | Grado-Ahuir, J., Aad, P., & Spicer, L. (2011). New insights into the pathogenesis of cystic follicles in cattle: microarray analysis of gene expression in granulosa cells. Journal of animal science, 89(6), 1769-1786. | spa |
| dc.relation.references | Grajales, H. (2008). Comportamiento reproductivo de grupos raciales bovinos en trópico cálido húmedo colombiano: pubertad, ciclo estral, preñez temprana, posparto, niveles de hormonas esteroides y su relación con la eficiencia reproductiva. . (Doctor en Ciencias), Universidad Nacional de Colombia. | spa |
| dc.relation.references | Grajales, H., Hernández, A., & Prieto, E. (2006). Determinación de parámetros reproductivos basado en los niveles de progesterona en novillas doble propósito en el trópico Colombiano. Livest Res Rural Develop, 18. | spa |
| dc.relation.references | Grazul-Bilska, A., Navanukraw, C., Johnson, M., Vonnahme, K., Ford, S., Reynolds, L., & Redmer, D. (2007). Vascularity and expression of angiogenic factors in bovine dominant follicles of the first follicular wave. Journal of animal science, 85(8), 1914-1922. | spa |
| dc.relation.references | Green, M., Hunter, M., & Mann, G. (2005). Relationships between maternal hormone secretion and embryo development on day 5 of pregnancy in dairy cows. Animal reproduction science, 88(3-4), 179-189. | spa |
| dc.relation.references | Gregson, E., Webb, R., Sheldrick, E. L., Campbell, B. K., Mann, G. E., Liddell, S., & Sinclair, K. D. (2016). Molecular determinants of a competent bovine corpus luteum: first-vs final-wave dominant follicles. Reproduction, 151(6), 563-575. | spa |
| dc.relation.references | Hammond, A., Olson, T., Chase, C., Bowers, E., Randel, R., Murphy, C., . . . Tewolde, A. (1996). Heat tolerance in two tropically adapted Bos taurus breeds, Senepol and Romosinuano, compared with Brahman, Angus, and Hereford cattle in Florida. Journal of animal science, 74(2), 295-303. | spa |
| dc.relation.references | Han, Z.-B., Lan, G.-C., Wu, Y.-G., Han, D., Feng, W.-G., Wang, J.-Z., & Tan, J.-H. (2006). Interactive effects of granulosa cell apoptosis, follicle size, cumulus–oocyte complex morphology, and cumulus expansion on the developmental competence of goat oocytes: a study using the well-in-drop culture system. Reproduction, 132(5), 749-758. | spa |
| dc.relation.references | Han, Z. B., Lan, G. C., Wu, Y. G., Han, D., Feng, W. G., Wang, J. Z., & Tan, J. H. (2006). Interactive effects of granulosa cell apoptosis, follicle size, cumulus-oocyte complex morphology, and cumulus expansion on the developmental competence of goat oocytes: a study using the well-in-drop culture system. Reproduction, 132(5), 749. | spa |
| dc.relation.references | Hansen, T. R., Bott, R., Romero, J., Antoniazzi, A., & Davis, J. S. (2017). Corpus luteum and early pregnancy in ruminants The Life Cycle of the Corpus Luteum (pp. 205-225): Springer. | spa |
| dc.relation.references | Henricks, D., Dickey, J., & Niswender, G. (1970). Serum luteinizing hormone and plasma progesterone levels during the estrous cycle and early pregnancy in cows. Biology of Reproduction, 2(3), 346-351. | spa |
| dc.relation.references | Hernández, A., & Jiménez, C. (2008). El ciclo estral. En: Reproducción en la vaca. Fisiología y aplicaciones. : Editorial Universidad Nacional de Colombia. | spa |
| dc.relation.references | Hirshfield, A. N. (1990). Development of follicles in the mammalian ovary. International review of cytology, 124, 43-101. | spa |
| dc.relation.references | Holdridge, L. R. (1967). Life zone ecology. Life zone ecology.(rev. ed.). | spa |
| dc.relation.references | Hsueh, A. J., Kawamura, K., Cheng, Y., & Fauser, B. C. (2015). Intraovarian control of early folliculogenesis. Endocrine reviews, 36(1), 1-24. | spa |
| dc.relation.references | Hurst, P. R., Mora, J. M., & Fenwick, M. A. (2006). Caspase-3, TUNEL and ultrastructural studies of small follicles in adult human ovarian biopsies. Human Reproduction, 21(8), 1974-1980. | spa |
| dc.relation.references | Jimenez-Krassel, F., Folger, J., Ireland, J., Smith, G., Hou, X., Davis, J., . . . Ireland, J. (2009). Evidence that high variation in ovarian reserves of healthy young adults has a negative impact on the corpus luteum and endometrium during estrous cycles in cattle. Biology of Reproduction, 80(6), 1272-1281. | spa |
| dc.relation.references | Johnson, A., Bridgham, J., & Wagner, B. (1996). Characterization of a chicken luteinizing hormone receptor (cLH-R) complementary deoxyribonucleic acid, and expression of cLH-R messenger ribonucleic acid in the ovary. Biology of Reproduction, 55(2), 304-309. | spa |
| dc.relation.references | Kaczmarek, M. M., Schams, D., & Ziecik, A. J. (2005). Role of vascular endothelial growth factor in ovarian physiology–an overview. Reprod Biol, 5(2), 111-136. | spa |
| dc.relation.references | Kaneko, H., Todoroki, J., Noguchi, J., Kikuchi, K., Mizoshita, K., Kubota, C., & Yamakuchi, H. (2002). Perturbation of estradiol-feedback control of luteinizing hormone secretion by immunoneutralization induces development of follicular cysts in cattle. Biology of Reproduction, 67(6), 1840-1845. | spa |
| dc.relation.references | Kaveh, A., Khelejani, M. V., Noei, F., Shahryari, A., Kordelar, M. J., Isaloo, P., . . . Irany, A. (2013). Evaluation of Relationship between Serum Progesterone levels and Size of Normal and Vacuolated Corpus Luteum and Comparison of Fertility in Holstein dairy cows. Bull. Env. Pharmacol. Life Sci, 3(1), 33-36. | spa |
| dc.relation.references | Kawate, N. (2004). Studies on the regulation of expression of luteinizing hormone receptor in the ovary and the mechanism of follicular cyst formation in ruminants. Journal of Reproduction and Development, 50(1), 1-8. | spa |
| dc.relation.references | Kayacik, V., Salmanoǧlu, M. R., Polat, B., & Özluer, A. (2006). Evaluation of the corpus luteum size throughout the cycle by ultrasonography and progesterone assay in cows. Turkish Journal of Veterinary and Animal Sciences, 29(6), 1311-1316. | spa |
| dc.relation.references | Kim, J. Y. (2012). Control of ovarian primordial follicle activation. Clinical and experimental reproductive medicine, 39(1), 10-14. | spa |
| dc.relation.references | Kotwica, J., Rekawiecki, R., & Duras, M. (2004). Stimulatory influence of progesterone on its own synthesis in bovine corpus luteum. BULLETIN-VETERINARY INSTITUTE IN PULAWY, 48(2), 139-146. | spa |
| dc.relation.references | Kotwica, J., & Williams, G. (1982). Relationship of plasma testosterone concentrations to pituitary-ovarian hormone secretion during the bovine estrous cycle and the effects of testosterone propionate administered during luteal regression. Biology of Reproduction, 27(4), 790-801. | spa |
| dc.relation.references | Kumar, R., Alwani, M., Kosta, S., Kaur, R., & Agarwal, S. (2017). BMP15 and GDF9 Gene Mutations in Premature Ovarian Failure. Journal of Reproduction & Infertility, 18(1), 185-189. | spa |
| dc.relation.references | Kumar, T. R., Wang, Y., Lu, N., & Matzuk, M. M. (1997). Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. Nature genetics, 15(2), 201-204. | spa |
| dc.relation.references | Larsson, B. (1987). Determination of Ovulation by Ultrasound Examination and its Relation to the LH‐Peak in Heifers. Journal of Veterinary Medicine Series A, 34(1‐10), 749-754. | spa |
| dc.relation.references | Lei, Z., Chegini, N., & Rao, C. V. (1991). Quantitative cell composition of human and bovine corpora lutea from various reproductive states. Biology of Reproduction, 44(6), 1148-1156. | spa |
| dc.relation.references | Li, P., Meng, J., Zhu, Z., Folger, J. K., & Lyu, L. (2018). Detection of Genes Associated with Follicle Development Through Transcriptome Analysis of Bovine Ovarian Follicles GCs. Current Bioinformatics, 13(2), 127-140. | spa |
| dc.relation.references | Liu, K.-C., Lin, S.-W., & Ge, W. (2011). Differential regulation of gonadotropin receptors (fshr and lhcgr) by estradiol in the zebrafish ovary involves nuclear estrogen receptors that are likely located on the plasma membrane. Endocrinology, 152(11), 4418-4430. | spa |
| dc.relation.references | Lodish, H. (2005). Biología celular y molecular: Ed. Médica Panamericana. | spa |
| dc.relation.references | Ma, T., Xiong, Q., Yuan, B., Jiang, H., Gao, Y., Xu, J., . . . Zhao, Y. (2012). Luteinizing hormone receptor splicing variants in bovine Leydig cells. Genet. Mol. Res., 11, 1721-1730. | spa |
| dc.relation.references | Mamluk, R., Wolfenson, D., & Meidan, R. (1998). LH receptor mRNA and cytochrome P450 side-chain cleavage expression in bovine theca and granulosa cells luteinized by LH or forskolin. Domestic Animal Endocrinology, 15(2), 103-114. | spa |
| dc.relation.references | Mann, G. (2009). Corpus luteum size and plasma progesterone concentration in cows. Animal reproduction science, 115(1), 296-299. | spa |
| dc.relation.references | Mann, G., Fray, M., & Lamming, G. (2006). Effects of time of progesterone supplementation on embryo development and interferon-τ production in the cow. The Veterinary Journal, 171(3), 500-503. | spa |
| dc.relation.references | Mann, G., Lamming, G., & Fray, M. (1995). Plasma oestradiol and progesterone during early pregnancy in the cow and the effects of treatment with buserelin. Animal reproduction science, 37(2), 121-131. | spa |
| dc.relation.references | Marsters, P., Kendall, N., & Campbell, B. (2015). Pre-translational regulation of luteinizing hormone receptor in follicular somatic cells of cattle. Animal reproduction science, 163, 63-74. | spa |
| dc.relation.references | Martínez-Villate, G. C., Martínez-Correal, G., & Manrique-Perdomo, C. (2009). Estimación de parámetros genéticos de características de crecimiento predestete del bovino criollo de raza sanmartinero (SM). Orinoquia, 13(2). | spa |
| dc.relation.references | McArdle, C., & Roberson, M. (2015). Gonadotropes and gonadotropin-releasing hormone signaling. Knobil and Neill’s Physiology of Reproduction, 4, 335-397. | spa |
| dc.relation.references | McCracken, J. A., Custer, E. E., & Lamsa, J. C. (1999). Luteolysis: a neuroendocrine-mediated event. Physiological reviews, 79(2), 263-323. | spa |
| dc.relation.references | McGee, E. A., & Hsueh, A. J. (2000). Initial and cyclic recruitment of ovarian follicles 1. Endocrine reviews, 21(2), 200-214. | spa |
| dc.relation.references | Medan, M. S., & El-Aty, A. A. (2010). Advances in ultrasonography and its applications in domestic ruminants and other farm animals reproduction. Journal of Advanced Research, 1(2), 123-128. | spa |
| dc.relation.references | Micevych, P., & Sinchak, K. (2008). Synthesis and function of hypothalamic neuroprogesterone in reproduction. Endocrinology, 149(6), 2739-2742. | spa |
| dc.relation.references | Micevych, P. E., Chaban, V., Ogi, J., Dewing, P., Lu, J. K., & Sinchak, K. (2007). Estradiol stimulates progesterone synthesis in hypothalamic astrocyte cultures. Endocrinology, 148(2), 782-789. | spa |
| dc.relation.references | Milazzotto, M., Rahal, P., Nichi, M., Miranda-Neto, T., Teixeira, L., Ferraz, J., . . . Garcia, J. (2008). New molecular variants of hypothalamus–pituitary–gonad axis genes and their association with early puberty phenotype in Bos taurus indicus (Nellore). Livestock Science, 114(2), 274-279. | spa |
| dc.relation.references | Mishra, S., Bharati, J., Rajesh, G., Chauhan, V., Sharma, G. T., Bag, S., . . . Sarkar, M. (2017). Fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor A (VEGFA) synergistically promote steroidogenesis and survival of cultured buffalo granulosa cells. Animal reproduction science, 179, 88-97. | spa |
| dc.relation.references | Monget, P., & Bondy, C. (2000). Importance of the IGF system in early folliculogenesis. Molecular and Cellular Endocrinology, 163(1), 89-93. | spa |
| dc.relation.references | Monget, P., Fabre, S., Mulsant, P., Lecerf, F., Elsen, J.-M., Mazerbourg, S., . . . Monniaux, D. (2002). Regulation of ovarian folliculogenesis by IGF and BMP system in domestic animals. Domestic Animal Endocrinology, 23(1), 139-154. | spa |
| dc.relation.references | Monsivais, D., Matzuk, M. M., & Pangas, S. A. (2017). The TGF-β Family in the Reproductive Tract. Cold Spring Harbor Perspectives in Biology, a022251. | spa |
| dc.relation.references | Mossa, F., Jimenez-Krassel, F., Folger, J. K., Ireland, J., Smith, G., Lonergan, P., . . . Ireland, J. J. (2010). Evidence that high variation in antral follicle count during follicular waves is linked to alterations in ovarian androgen production in cattle. Reproduction, 140(5), 713. | spa |
| dc.relation.references | Mukasa-Mugerwa, E., & Tegegne, A. (1989). Peripheral plasma progesterone concentration in zebu (Bos indicus) cows during pregnancy. Reproduction Nutrition Development, 29(3), 303-306. | spa |
| dc.relation.references | Nejad, S. Z., Tehrani, F. R., & Zadeh-Vakili, A. (2017). The Role of Kisspeptin in Female Reproduction. International Journal of Endocrinology and Metabolism(In Press). | spa |
| dc.relation.references | Niemann, H., Sacher, B., & Elsaesser, F. (1985). Pregnancy rates relative to recipient plasma progesterone levels on the day of nonsurgical transfer of frozen/thawed bovine embryos. Theriogenology, 23(4), 631-639. | spa |
| dc.relation.references | Niswender, G., Schwall, R., Fitz, T., Farin, C., & Sawyer, H. (2013). Regulation of luteal function in domestic ruminants: new concepts. Recent Prog Horm Resl985, 41, 101-151. | spa |
| dc.relation.references | Niswender, G. D., Juengel, J. L., Silva, P. J., Rollyson, M. K., & McIntush, E. W. (2000). Mechanisms controlling the function and life span of the corpus luteum. Physiological reviews, 80(1), 1-29. | spa |
| dc.relation.references | Nivet, A. L., Vigneault, C., Blondin, P., & Sirard, M. A. (2018). Influence of luteinizing hormone support on granulosa cells transcriptome in cattle. Animal Science Journal, 89(1), 21-30. | spa |
| dc.relation.references | Nogueira, M., Buratini, J., Price, C., Castilho, A., Pinto, M., & Barros, C. (2007). Expression of LH receptor mRNA splice variants in bovine granulosa cells: changes with follicle size and regulation by FSH in vitro. Molecular reproduction and development, 74(6), 680-686. | spa |
| dc.relation.references | Nogueira, M. F. G., Fernandes, P., Ereno, R. L., Simões, R. A. L., Buratini Júnior, J., & Barros, C. M. (2010). Luteinizing Hormone Receptor (LHR): basic concepts in cattle and other mammals. A review. Animal Reproduction, 51-64. | spa |
| dc.relation.references | O'shea, J. (1986). Heterogeneous cell types in the corpus luteum of sheep, goats and cattle. Journal of reproduction and fertility. Supplement, 34, 71-85. | spa |
| dc.relation.references | O'shea, J., Rodgers, R., & D'occhio, M. (1989). Cellular composition of the cyclic corpus luteum of the cow. Journal of reproduction and fertility, 85(2), 483-487. | spa |
| dc.relation.references | Osorio, M., & León, F. (1998). Diversidad y relaciones filogenéticas del ganado criollo colomiano. Retrieved from | spa |
| dc.relation.references | Ossa, G. A., & Suárez, M. A. (2007). Factores ambientales y genéticos que influyen la edad al primer parto y el intervalo entre partos en hembras de la raza criolla Romosinuano. Corpoica Ciencia y Tecnología Agropecuaria, 8(2), 74-80. | spa |
| dc.relation.references | Parr, R., Davis, I., Miles, M., & Squires, T. (1993). Liver blood flow and metabolic clearance rate of progesterone in sheep. Research in Veterinary Science, 55(3), 311-316. | spa |
| dc.relation.references | Peiró, J. R., Nogueira, G. M., Nogueira, G. P., Perri, S. H., & Cardoso, D. (2009). Ovariectomy by left flank approach in prepubertal Nelore (Bos indicus) heifers. Canadian Journal of Veterinary Research, 73(3), 237. | spa |
| dc.relation.references | Peng, X.-R., Hsue, A. J., Lapolt, P. S., Bjerrsing, L., & Ny, T. (1991). Localization of luteinizing hormone receptor messenger ribonucleic acid expression in ovarian cell types during follicle development and ovulation. Endocrinology, 129(6), 3200-3207. | spa |
| dc.relation.references | Peña, M., Góngora, A., & Estrada, J. (2007). Growth factors in the follicular development, embryonic early and implantation. Implications in the production of bovine embryos. Revista MVZ Córdoba, 12(1), 942-954. | spa |
| dc.relation.references | Perry, G. A., Smith, M. F., Lucy, M. C., Green, J. A., Parks, T. E., MacNeil, M. D., . . . Geary, T. W. (2005). Relationship between follicle size at insemination and pregnancy success. Proceedings of the National Academy of Sciences of the United States of America, 102(14), 5268-5273. | spa |
| dc.relation.references | Pierson, R., & Ginther, O. (1984). Ultrasonography of the bovine ovary. Theriogenology, 21(3), 495-504. | spa |
| dc.relation.references | Pierson, R., & Ginther, O. (1988). Ultrasonic imaging of the ovaries and uterus in cattle. Theriogenology, 29(1), 21-37. | spa |
| dc.relation.references | Pinheiro, O., Barros, C., Figueiredo, R., Do Valle, E., Encarnação, R., & Padovani, C. (1998). Estrous behavior and the estrus-to-ovulation interval in nelore cattle (Bosindicus with natural estrus or estrus induced with prostaglandin F2α or norgestomet and estradiol valerate. Theriogenology, 49(3), 667-681. | spa |
| dc.relation.references | Plasse, D., Warnick, A., Reese, R., & Koger, M. (1968). Reproductive Behavior of Bos Indicus Females in a Subtropical Environment. II. Gestation Length in Brahman Cattle 1. Journal of animal science, 27(1), 101-104. | spa |
| dc.relation.references | Rahe, C., Owens, R., Fleeger, J., Newton, H., & Harms, P. (1980). Pattern of plasma luteinizing hormone in the cyclic cow: dependence upon the period of the cycle. Endocrinology, 107(2), 498-503. | spa |
| dc.relation.references | Rajakoski, E. (1960). The ovarian follicular system in sexually mature heifers with special reference to seasonal, cyclical, and left-right variations. Acta endocrinologica, 34(3 Suppl), S7-S68. | spa |
| dc.relation.references | Rajamahendran, R., Ambrose, D. J., & Burton, B. (1994). Clinical and research applications of real-time ultrasonography in bovine reproduction: a review. The Canadian Veterinary Journal, 35(9), 563. | spa |
| dc.relation.references | Rawan, A., Yoshioka, S., Abe, H., & Acosta, T. (2015). Insulin‐Like Growth Factor‐1 Regulates the Expression of Luteinizing Hormone Receptor and Steroid Production in Bovine Granulosa Cells. Reproduction in Domestic Animals, 50(2), 283-291. | spa |
| dc.relation.references | Rekawiecki, R., & Kotwica, J. (2007). Molecular regulation of progesterone synthesis in the bovine corpus luteum. VETERINARNI MEDICINA-PRAHA-, 52(9), 405. | spa |
| dc.relation.references | Rekawiecki, R., Kowalik, M., Slonina, D., & Kotwica, J. (2008). Regulation of progesterone synthesis and action in bovine corpus luteum. J Physiol Pharmacol, 59(suppl 9), 75-89. | spa |
| dc.relation.references | Remsen, L., Roussel, J., & Karihaloo, A. (1982). Pregnancy rates relating to plasma progesterone levels in recipient heifers at day of transfer. Theriogenology, 18(3), 365-372. | spa |
| dc.relation.references | Rhodes, F., De'Ath, G., & Entwistle, K. (1995). Animal and temporal effects on ovarian follicular dynamics in Brahman heifers. Animal reproduction science, 38(4), 265-277. | spa |
| dc.relation.references | Richards, J., & Hedin, L. (1988). Molecular aspects of hormone action in ovarian follicular development, ovulation, and luteinization. Annual Review of Physiology, 50(1), 441-463. | spa |
| dc.relation.references | Rimon-Dahari, N., Yerushalmi-Heinemann, L., Alyagor, L., & Dekel, N. (2016). Ovarian Folliculogenesis Molecular Mechanisms of Cell Differentiation in Gonad Development (pp. 167-190): Springer. | spa |
| dc.relation.references | Rizov, M., Andreeva, P., & Dimova, I. (2017). Molecular regulation and role of angiogenesis in reproduction. Taiwanese Journal of Obstetrics and Gynecology, 56(2), 127-132. | spa |
| dc.relation.references | Robert, C., Gagne, D., Lussier, J., Bousquet, D., Barnes, F., & Sirard, M. (2003). Presence of LH receptor mRNA in granulosa cells as a potential marker of oocyte developmental competence and characterization of the bovine splicing isoforms. Reproduction, 125(3), 437-446. | spa |
| dc.relation.references | Robertson, H. (1972). Sequential changes in plasma progesterone in the cow during the estrous cycle, pregnancy, at parturition, and post-partum. Canadian journal of animal science, 52(4), 645-658. | spa |
| dc.relation.references | Robinson, R., Hammond, A., Hunter, M., & Mann, G. (2005). The induction of a delayed post-ovulatory progesterone rise in dairy cows: a novel model. Domestic Animal Endocrinology, 28(3), 285-295. | spa |
| dc.relation.references | Robker, R., Russell, D., Espey, L. L., Lydon, J., O'Malley, B., & Richards, J. (2000). Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases. Proceedings of the National Academy of Sciences, 97(9), 4689-4694. | spa |
| dc.relation.references | Rodgers, R. J., & Irving-Rodgers, H. F. (2010). Formation of the ovarian follicular antrum and follicular fluid. Biology of Reproduction, 82(6), 1021-1029. | spa |
| dc.relation.references | Rodriguez, A., Matzuk, M. M., & Pangas, S. A. (2019). Growth Factors and Reproduction Yen and Jaffe's Reproductive Endocrinology (Eighth Edition) (pp. 132-148. e134): Elsevier. | spa |
| dc.relation.references | Rybska, M., Knap, S., Jankowski, M., Jeseta, M., Bukowska, D., Antosik, P., . . . Jaśkowski, J. M. (2018). Characteristic of factors influencing the proper course of folliculogenesis in mammals. Medical Journal of Cell Biology, 6(1), 33-38. | spa |
| dc.relation.references | Sartori, Spies, C., & Wiltbank, M. C. (2017). Effects of dry matter and energy intake on quality of oocytes and embryos in ruminants. Reproduction, Fertility and Development, 29(1), 58-65. | spa |
| dc.relation.references | Sartori, R., Bastos, M., Baruselli, P., Gimenes, L., Ereno, R., & Barros, C. (2010). Physiological differences and implications to reproductive management of Bos taurus and Bos indicus cattle in a tropical environment. Reprod Domest Rumin Vii, 67, 357-375. | spa |
| dc.relation.references | Sartori, R., Fricke, P. M., Ferreira, J. C., Ginther, O., & Wiltbank, M. C. (2001). Follicular deviation and acquisition of ovulatory capacity in bovine follicles. Biology of Reproduction, 65(5), 1403-1409. | spa |
| dc.relation.references | Sartori, R., Rosa, G., & Wiltbank, M. (2002). Ovarian structures and circulating steroids in heifers and lactating cows in summer and lactating and dry cows in winter. Journal of dairy science, 85(11), 2813-2822. | spa |
| dc.relation.references | Schams, D., Hoffmann, B., Fischer, S., Marz, E., & Karg, H. (1972). Simultaneous determination of LH and progesterone in peripheral bovine blood during pregnancy, normal and corticoid-induced parturition and the post-partum period. Journal of reproduction and fertility, 29(1), 37-48. | spa |
| dc.relation.references | Schams, D., & Karg, H. (1969). Radioimmunologische LH-Bestimmung im Blutserum vom Rind unter besonderer Berücksichtigung des Brunstzyklus. Acta endocrinologica, 61(1), 96-103. | spa |
| dc.relation.references | Schoenemann, H., Humphrey, W., Crowder, M., Nett, T., & Reeves, J. (1985). Pituitary luteinizing hormone-releasing hormone receptors in ovariectomized cows after challenge with ovarian steroids. Biology of Reproduction, 32(3), 574-583. | spa |
| dc.relation.references | Senger. (2012). Pathways to pregnancy and parturition. Redmond: Current Conceptions: Inc. | spa |
| dc.relation.references | Senger, P. L. (1997). Pathways to pregnancy and parturition: Current Conceptions, Inc., 1615 NE Eastgate Blvd. | spa |
| dc.relation.references | Shi, Y. (2002). Mechanisms of caspase activation and inhibition during apoptosis. Molecular cell, 9(3), 459-470. | spa |
| dc.relation.references | Shirasuna, K., Jiemtaweeboon, S., Raddatz, S., Nitta, A., Schuberth, H.-J., Bollwein, H., . . . Miyamoto, A. (2012). Rapid accumulation of polymorphonuclear neutrophils in the corpus luteum during prostaglandin F 2α-induced luteolysis in the cow. PloS one, 7(1), e29054. | spa |
| dc.relation.references | Silva, J., Figueiredo, J., & Van den Hurk, R. (2009). Involvement of growth hormone (GH) and insulin-like growth factor (IGF) system in ovarian folliculogenesis. Theriogenology, 71(8), 1193-1208. | spa |
| dc.relation.references | Siqueira, L. G. B., Torres, C. A., Amorim, L. S., Souza, E. D., Camargo, L. S. A., Fernandes, C. A., & Viana, J. H. M. (2009). Interrelationships among morphology, echotexture, and function of the bovine corpus luteum during the estrous cycle. Animal reproduction science, 115(1-4), 18-28. | spa |
| dc.relation.references | Sirois, J., & Fortune, J. (1988). Ovarian follicular dynamics during the estrous cycle in heifers monitored by real-time ultrasonography. Biology of Reproduction, 39(2), 308-317. | spa |
| dc.relation.references | Skarzynski, D., Ferreira‐Dias, G., & Okuda, K. (2008). Regulation of luteal function and corpus luteum regression in cows: hormonal control, immune mechanisms and intercellular communication. Reproduction in Domestic Animals, 43(s2), 57-65. | spa |
| dc.relation.references | Sleiter, N., Pang, Y., Park, C., Horton, T. H., Dong, J., Thomas, P., & Levine, J. E. (2009). Progesterone receptor A (PRA) and PRB-independent effects of progesterone on gonadotropin-releasing hormone release. Endocrinology, 150(8), 3833-3844. | spa |
| dc.relation.references | Smith, M., McIntush, E., & Smith, G. (1994). Mechanisms associated with corpus luteum development. Journal of animal science, 72(7), 1857-1872. | spa |
| dc.relation.references | Song, Y. S., Ji, I., Beauchamp, J., Isaacs, N. W., & Ji, T. H. (2001). Hormone Interactions to Leu-rich Repeats in the Gonadotropin Receptors I. ANALYSIS OF LEU-RICH REPEATS OF HUMAN LUTEINIZING HORMONE/CHORIONIC GONADOTROPIN RECEPTOR AND FOLLICLE-STIMULATING HORMONE RECEPTOR. Journal of Biological Chemistry, 276(5), 3426-3435. | spa |
| dc.relation.references | Spell, A., Beal, W., Corah, L., & Lamb, G. (2001). Evaluating recipient and embryo factors that affect pregnancy rates of embryo transfer in beef cattle. Theriogenology, 56(2), 287-297. | spa |
| dc.relation.references | Spicer, L., & Echternkamp, S. (1986). Ovarian follicular growth, function and turnover in cattle: a review. Journal of animal science, 62(2), 428-451. | spa |
| dc.relation.references | Spicer, L. J., Aad, P. Y., Allen, D. T., Mazerbourg, S., Payne, A. H., & Hsueh, A. J. (2008). Growth differentiation factor 9 (GDF9) stimulates proliferation and inhibits steroidogenesis by bovine theca cells: influence of follicle size on responses to GDF9. Biology of Reproduction, 78(2), 243-253. | spa |
| dc.relation.references | Stabenfeldt, G., Ewing, L., & McDonald, L. (1969). Peripheral plasma progesterone levels during the bovine oestrous cycle. Journal of reproduction and fertility, 19(3), 433-442. | spa |
| dc.relation.references | Taylor, P., Wilson, H., Hillier, S., Wiegand, S., & Fraser, H. (2007). Effects of inhibition of vascular endothelial growth factor at time of selection on follicular angiogenesis, expansion, development and atresia in the marmoset. Molecular human reproduction, 13(10), 729-736. | spa |
| dc.relation.references | Tena-Sempere, M. (2006). GPR54 and kisspeptin in reproduction. Human Reproduction Update, 12(5), 631-639. | spa |
| dc.relation.references | Thompson, I. R., & Kaiser, U. B. (2014). GnRH pulse frequency-dependent differential regulation of LH and FSH gene expression. Molecular and Cellular Endocrinology, 385(1), 28-35. | spa |
| dc.relation.references | Tomac, J., Cekinović, Đ., & Arapović, J. (2011). Biology of the corpus luteum. Periodicum biologorum, 113(1), 43-49. | spa |
| dc.relation.references | Tortorella, R. D., de Paula Nogueira, G., Modesto, M. R., Silva, P. C. P., da Silva, J. P., Neves, J. P., & Ramos, A. F. (2017). Characterizing emergence and divergence in the first follicular wave in a tropically adapted Bos taurus breed. Theriogenology, 88, 9-17. | spa |
| dc.relation.references | Totty, M., Morrell, B., & Spicer, L. (2017). Fibroblast growth factor 9 (FGF9) regulation of cyclin D1 and cyclin-dependent kinase-4 in ovarian granulosa and theca cells of cattle. Molecular and Cellular Endocrinology, 440, 25-33. | spa |
| dc.relation.references | Townson, D., Tsang, P., Butler, W., Frajblat, M., Griel, L., Johnson, C., . . . Pate, J. (2002). Relationship of fertility to ovarian follicular waves before breeding in dairy cows. Journal of animal science, 80(4), 1053-1058. | spa |
| dc.relation.references | Tsutsui, K. (2008). Progesterone biosynthesis and action in the developing neuron. Endocrinology, 149(6), 2757-2761. | spa |
| dc.relation.references | Van Tol, H., Van Eijk, M., Mummery, C., Van Den Hurk, R., & Bevers, M. (1996). Influence of FSH and hCG on the resumption of meiosis of bovine oocytes surrounded by cumulus cells connected to membrana granulosa. Molecular reproduction and development, 45(2), 218-224. | spa |
| dc.relation.references | Vasconcelos, J., Sartori, R., Oliveira, H., Guenther, J., & Wiltbank, M. (2001). Reduction in size of the ovulatory follicle reduces subsequent luteal size and pregnancy rate. Theriogenology, 56(2), 307-314. | spa |
| dc.relation.references | Vejarano A, O. F., Gómez VH, Vélez G, Suárez AA, Villa NA. (2003). Estudio de la dinámica ovárica durante un ciclo estral en novillas Brahman y su relación con los niveles de progesterona. . Paper presented at the IV Seminario internacional de reproducción en grandes animales. | spa |
| dc.relation.references | Villavicencio, J. L. E., Pérez, R. O., Palacios-Espinosa, A., Méndez, J. V., & Flores, C. F. A. (2007). Crecimiento folicular ovárico en animales domésticos: una revisión. Interciencia: Revista de ciencia y tecnología de América, 32(2), 93-99. | spa |
| dc.relation.references | Walker, S., Smith, R., Jones, D., Routly, J., & Dobson, H. (2008). Chronic stress, hormone profiles and estrus intensity in dairy cattle. Hormones and Behavior, 53(3), 493-501. | spa |
| dc.relation.references | Walker, W., Nebel, R., & McGilliard, M. (1996). Time of ovulation relative to mounting activity in dairy cattle. Journal of dairy science, 79(9), 1555-1561. | spa |
| dc.relation.references | Woad, K. J. Luteal angiogenesis and its control. Theriogenology, 86(1), 221. | spa |
| dc.relation.references | Woad, K. J., & Robinson, R. S. (2016). Luteal angiogenesis and its control. Theriogenology, 86(1), 221-228. | spa |
| dc.relation.references | Xu, Z., Garverick, H. A., Smith, G. W., Smith, M. F., Hamilton, S. A., & Youngquist, R. S. (1995). Expression of follicle-stimulating hormone and luteinizing hormone receptor messenger ribonucleic acids in bovine follicles during the first follicular wave. Biology of Reproduction, 53(4), 951-957. | spa |
| dc.relation.references | Yang, M., Cushman, R., & Fortune, J. (2017). Anti-Müllerian hormone inhibits activation and growth of bovine ovarian follicles in vitro and is localized to growing follicles. Molecular human reproduction, 1. | spa |
| dc.relation.references | Yang, M. Y., & Fortune, J. E. (2007). Vascular endothelial growth factor stimulates the primary to secondary follicle transition in bovine follicles in vitro. Mol Reprod Dev, 74(9), 1095-1104. doi:10.1002/mrd.20633 | spa |
| dc.relation.references | Young, J., & McNeilly, A. S. (2010). Theca: the forgotten cell of the ovarian follicle. Reproduction, 140(4), 489-504. | spa |
| dc.relation.references | Youngquist, R. S., & Threlfall, W. R. (2006). Current therapy in large animal theriogenology: Elsevier Health Sciences. | spa |
| dc.relation.references | Yung, M., VandeHaar, M., Fogwell, R., & Sharma, B. (1996). Effect of energy balance and somatotropin on insulin-like growth factor I in serum and on weight and progesterone of corpus luteum in heifers. Journal of animal science, 74(9), 2239-2244. | spa |
| dc.relation.references | Abdennebi, L., Lesport, A., Remy, J., Grebert, D., Pisselet, C., Monniaux, D., & Salesse, R. (2002). Differences in splicing of mRNA encoding LH receptor in theca cells according to breeding season in ewes. Reproduction, 123(6), 819-826. | spa |
| dc.relation.references | Abel, M. H., Wootton, A. N., Wilkins, V., Huhtaniemi, I., Knight, P. G., & Charlton, H. M. (2000). The Effect of a Null Mutation in the Follicle-Stimulating Hormone Receptor Gene on Mouse Reproduction 1. Endocrinology, 141(5), 1795-1803. | spa |
| dc.relation.references | Abreu, F., da Silva, M. C., Cruppe, L., Mussard, M., Bridges, G., Harstine, B., . . . Day, M. (2018). Role of progesterone concentrations during early follicular development in beef cattle: I. Characteristics of LH secretion and oocyte quality. Animal reproduction science, 196, 59-68. | spa |
| dc.relation.references | Acosta, T. J. (2007). Studies of follicular vascularity associated with follicle selection and ovulation in cattle. Journal of Reproduction and Development, 53(1), 39-44. | spa |
| dc.relation.references | Adams, G., Jaiswal, R., Singh, J., & Malhi, P. (2008). Progress in understanding ovarian follicular dynamics in cattle. Theriogenology, 69(1), 72-80. | spa |
| dc.relation.references | Adams, G. P., Matteri, R., Kastelic, J., Ko, J., & Ginther, O. (1992). Association between surges of follicle-stimulating hormone and the emergence of follicular waves in heifers. Journal of reproduction and fertility, 94(1), 177-188. | spa |
| dc.relation.references | Adams, G. P., & Singh, J. (2015). Ovarian follicular and luteal dynamics in cattle. Bovine reproduction, 219-244. | spa |
| dc.relation.references | Aerts, J., & Bols, P. (2010). Ovarian follicular dynamics. A review with emphasis on the bovine species. Part II: Antral development, exogenous influence and future prospects. Reproduction in Domestic Animals, 45(1), 180-187. | spa |
| dc.relation.references | Araújo, V., Silva, G., Duarte, A., Magalhães, D., Almeida, A., Gonçalves, R., . . . Rodrigues, A. (2011). Vascular endothelial growth factor-A165 (VEGF-A165) stimulates the in vitro development and oocyte competence of goat preantral follicles. Cell and tissue research, 346(2), 273-281. | spa |
| dc.relation.references | Araújo, V. R., Duarte, A. B. G., Bruno, J. B., Lopes, C. A. P., & de Figueiredo, J. R. (2013). Importance of vascular endothelial growth factor (VEGF) in ovarian physiology of mammals. Zygote, 21(3), 295. | spa |
| dc.relation.references | Asadi, E., Najafi, A., Moeini, A., Pirjani, R., Hassanzadeh, G., Mikaeili, S., . . . Khosravi, F. (2017). Ovarian tissue culture in the presence of VEGF and fetuin stimulates follicle growth and steroidogenesis. Journal of Endocrinology, 232(2), 205-219. | spa |
| dc.relation.references | Badinga, L., Collier, R. J., Thatcher, W., & Wilcox, C. (1985). Effects of climatic and management factors on conception rate of dairy cattle in subtropical environment. Journal of dairy science, 68(1), 78-85. | spa |
| dc.relation.references | Bao, B., Garverick, H. A., Smith, G. W., Smith, M. F., Salfen, B. E., & Youngquist, R. S. (1997). Changes in messenger ribonucleic acid encoding luteinizing hormone receptor, cytochrome P450-side chain cleavage, and aromatase are associated with recruitment and selection of bovine ovarian follicles. Biology of Reproduction, 56(5), 1158-1168. | spa |
| dc.relation.references | Barros, C. M., Ereno, R. L., Simões, R. A., Fernandes, P., Buratini, J., & Nogueira, M. F. (2009). Use of knowledge regarding LH receptors to improve superstimulatory treatments in cattle. Reproduction, Fertility and Development, 22(1), 132-137. | spa |
| dc.relation.references | Beg, M., & Ginther, O. (2006). Follicle selection in cattle and horses: role of intrafollicular factors. Reproduction, 132(3), 365-377. | spa |
| dc.relation.references | Berardinelli, J., Dailey, R., Butcher, R., & Inskeep, E. (1979). Source of progesterone prior to puberty in beef heifers. Journal of animal science, 49(5), 1276-1280. | spa |
| dc.relation.references | Berisha, B., & Schams, D. (2005). Ovarian function in ruminants. Domestic Animal Endocrinology, 29(2), 305-317. | spa |
| dc.relation.references | Berisha, B., Schams, D., Rodler, D., & Pfaffl, M. W. (2015). Angiogenesis in the ovary–the most important regulatory event for follicle and corpus luteum development and function in cow–An overview. Anatomia, histologia, embryologia. | spa |
| dc.relation.references | Borges, A., Torres, C., Rocha Júnior, V., Ruas, J., Gioso, M., Fonseca, J., . . . Maffili, V. (2004). Follicular dynamic and ovulation time of non-lactating Gir and Nelore cows during two seasons of the year. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 56(3), 346-354. | spa |
| dc.relation.references | Braun, T., Schofield, P. R., & Sprengel, R. (1991). Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity. The EMBO journal, 10(7), 1885. | spa |
| dc.relation.references | Bulman, D. C., & Lamming, G. (1978). Milk progesterone levels in relation to conception, repeat breeding and factors influencing acyclicity in dairy cows. Journal of reproduction and fertility, 54(2), 447-458. | spa |
| dc.relation.references | Cacioppo, J. A., Lin, P.-C. P., Hannon, P. R., McDougle, D. R., Gal, A., & Ko, C. (2017). Granulosa cell endothelin-2 expression is fundamental for ovulatory follicle rupture. Scientific reports, 7. | spa |
| dc.relation.references | Cadagan, D., & Towlson, C. (2017). Mechanisms of Luteinising Hormone Regulation in Female Steroidogenesis. American Journal of Medical Case Reports, 5(3), 65-68. | spa |
| dc.relation.references | Casarini, L., Huhtaniemi, I., Simoni, M., & Rivero-Müller, A. (2017). Gonadotrophin Receptors. Endocrinology of the Testis and Male Reproduction, 1-46. | spa |
| dc.relation.references | Casarini, L., Pignatti, E., & Simoni, M. (2011). Effects of polymorphisms in gonadotropin and gonadotropin receptor genes on reproductive function. Reviews in Endocrine and Metabolic Disorders, 12(4), 303. | spa |
| dc.relation.references | Casarini, L., Santi, D., Gary, R. M., & Simoni, M. (2018). LH (Luteinizing Hormone). | spa |
| dc.relation.references | Castilho, A., Price, C., Dalanezi, F., Ereno, R., Machado, M., Barros, C., . . . Buratini, J. (2017). Evidence that fibroblast growth factor 10 plays a role in follicle selection in cattle. Reproduction, Fertility and Development, 29(2), 234-243. | spa |
| dc.relation.references | Cattanach, B., Iddon, C. A., Charlton, H., Chiappa, S. A., & Fink, G. (1977). Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism. Nature, 269(5626), 338-340. | spa |
| dc.relation.references | Cavalieri, J., Rubio, I., Kinder, J., Entwistle, K., & Fitzpatrick, L. (1997). Synchronization of estrus and ovulation and associated endocrine changes in Bos indicus cows. Theriogenology, 47(4), 801-814. | spa |
| dc.rights | Derechos reservados - Universidad Nacional de Colombia | spa |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.license | Atribución-NoComercial-SinDerivadas 4.0 Internacional | spa |
| dc.rights.spa | Acceso abierto | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | spa |
| dc.subject.ddc | 636 - Producción animal (Zootecnia) | spa |
| dc.subject.proposal | LHR/LHCGR | eng |
| dc.subject.proposal | LHR/LHCGR | spa |
| dc.subject.proposal | bovinos | spa |
| dc.subject.proposal | bovine | eng |
| dc.subject.proposal | granulosa cells | eng |
| dc.subject.proposal | granulosa | spa |
| dc.subject.proposal | teca interna | spa |
| dc.subject.proposal | inner theca cells | eng |
| dc.title | Expresión de receptores para la hormona luteinizante y su ácido ribonucléico mensajero en folículos preovulatorios de vacas Romosinuano y Brahman - posible relación con los niveles séricos de progesterona | spa |
| dc.type | Trabajo de grado - Doctorado | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_db06 | spa |
| dc.type.coarversion | http://purl.org/coar/version/c_ab4af688f83e57aa | spa |
| dc.type.content | Text | spa |
| dc.type.driver | info:eu-repo/semantics/doctoralThesis | spa |
| dc.type.version | info:eu-repo/semantics/acceptedVersion | spa |
| oaire.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |