Algas pardas de la Isla de San Andrés, Caribe Colombiano: Caracterización metabolómica

Vista sencilla de ítem
dc.contributor.advisorRamos Rodriguez, Freddy Alejandro
dc.contributor.advisorPuyana Hegedus, Mónica
dc.contributor.authorde la Roche Zogby, Felipe
dc.contributor.researchgroupEstudio y Aprovechamiento de Productos Naturales Marinos y Frutas de Colombiaspa
dc.coverage.citySan Andrés - Isla
dc.coverage.countryColombia
dc.date.accessioned2023-07-31T21:07:08Z
dc.date.available2023-07-31T21:07:08Z
dc.date.issued2022
dc.descriptionilustraciones, diagramas, fotografíasspa
dc.description.abstractDesde finales de los años 70 los arrecifes coralinos del Mar Caribe han sufrido un deterioro notable y progresivo, causado por factores como la contaminación, sobrepesca y el cambio climático, esta situación ha generado que las poblaciones de corales sean reemplazadas por otros organismos bentónicos principalmente por algas pardas, las cuales presentan rápido crecimiento y la producción de metabolitos especializados los cuales cumplen funciones ecológicas. Debido a su alta abundancia y potencial bioactivo se realizó un se estudiaron las algas pardas que habitan los ecosistemas marinos someros al norte de la isla de San Andrés. En este estudio, a partir del análisis de la abundancia, riqueza y perfilado metabólico de las especies de algas pardas más abundantes, recolectadas en 5 colectas distintas, se pudo determinar que especies como Dictyoperis delicatula o Padina gymnospora produjeron compuestos lipídicos principalmente, mientras que otras como Stypopodium zonale produjeron meroditerpenos como metabolitos especializados. En esta especie, los perfiles metabólicos se vieron influenciados por el sustrato de colecta. La especie Canistrocarpus crispatus fue seleccionada para un estudio químico más detallado ya que presentó perfiles metabólicos ricos en diterpenos, además de ser el alga más abundante en dos fechas de colecta. A partir de C. crispatus se identificaron los diterpenos pachydictyol A, isopachydictyol A y acetato de dictyol B, compuestos con potentes propiedades disuasorios de la herbivoría contra peces y varios tipos de invertebrados, además de la fucoxantina, pigmento fotosintético característico de las algas pardas. Este trabajo representa la primera aproximación a la descripción de la composición química de las algas pardas de la Isla de San Andrés. Palabras (Texto tomado de la fuente)spa
dc.description.abstractSince the end of the 1970s, coral reefs in the Caribbean Sea have suffered a notable and progressive decline, generated by factors such as pollution, overfishing, and climate change. This situation has caused coral populations to be replaced by other benthic organisms, mainly brown algae, which have rapid growth and the production of specialized metabolites which fulfill ecological functions. Due to its high abundance and bioactive potential, a study was made of the brown algae that inhabit the shallow marine ecosystems north of the island of San Andrés. In this study, based on the analysis of the abundance, richness, and metabolic profile of the most abundant brown algae species, collected in 5 different collections, it was possible to determine which species such as Dictyoperis delicatula or Padina gymnospora produced mainly lipid compost, while others such as Stypopodium zonale produced meroditerpenes as specialized metabolites. In this species, the metabolic profiles were influenced by the collection substrate. The species Canistrocarpus crispatus was selected for a more detailed chemical study since it presented metabolic profiles rich in diterpenes, in addition to being the most abundant algae in two collection dates. From C. crispatus, the diterpenes pachydictyol A, isopachydictyol A, and dictyol B acetate were identified, compounds with powerful herbivory deterrent properties against fish and various types of invertebrates, in addition to fucoxanthin, a photosynthetic pigment characteristic of brown algae. This work represents the first approach to the description of the chemical composition of the brown algae of San Andrés Island.eng
dc.description.degreelevelMaestríaspa
dc.description.researchareaLínea de Investigación en Productos Naturalesspa
dc.format.extent158 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameUniversidad Nacional de Colombiaspa
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombiaspa
dc.identifier.repourlhttps://repositorio.unal.edu.co/spa
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/84384
dc.language.isospaspa
dc.publisherUniversidad Nacional de Colombiaspa
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotáspa
dc.publisher.facultyFacultad de Cienciasspa
dc.publisher.placeBogotá,Colombiaspa
dc.publisher.programBogotá - Ciencias - Maestría en Ciencias - Químicaspa
dc.relation.referencesKumar, H.; Singh, H. A Textbook on Algae; Affiliated East-West Press, 1976spa
dc.relation.referencesThe Algae World; Sahoo, D., Seckbach, J., Eds.; Cellular origin, life in extreme habitats and astrobiology; Springer: Dordrecht Heidelberg New York London, 2015spa
dc.relation.referencesLee, R. E. Phycology, Fourth Edition, 4th ed.; Cambridge University Press: New York, 2008spa
dc.relation.referencesGraham, J.; Wilcox, L.; Graham, L. Algae, segunda.; Benjamin Cummings: San Francisco, Estados Unidos, 2008spa
dc.relation.referencesGerasimenko, N. I.; Skriptsova, A. V.; Busarova, N. G.; Moiseenko, O. P. Effects of the Season and Growth Stage on the Contents of Lipids and Photosynthetic Pigments in Brown Alga Undaria Pinnatifida. Russ. J. Plant Physiol. 2011, 58 (5), 885–891.spa
dc.relation.referencesD’Orazio, N.; Gemello, E.; Gammone, M.; de Girolamo, M.; Ficoneri, C.; Riccioni, G. Fucoxantin: A Treasure from the Sea. Mar. Drugs 2012, 10 (12), 604–616spa
dc.relation.referencesSulistiyani, Y.; Sabdono, A.; Afiati, N.; Haeruddin, H. Fucoxanthin Identification and Purification of Brown Algae Commonly Found in Lombok Island, Indonesia. Biodiversitas J. Biol. Divers. 2021, 22 (3)spa
dc.relation.referencesKloareg, B.; Quatrano, R. Structure of the Cell Walls of Marine Algae and Ecophysiological Functions of the Matrix Polysaccharides. Oceanogr. Mar. Biol. Annu. Rev. 1988, 26, 259-315spa
dc.relation.referencesCai, J.; Lovatelli, A.; Garrido, E.; Geehuan, J.; Lucente, D.; Mair, G. Seaweeds and Microalgae: An Overview for Unlocking Their Potential in Global Aquaculture Development; 1229; FAO Fisheries and Aquaculture Circular: Rome, 2021; p 36spa
dc.relation.referencesHoltkamp, A. D.; Kelly, S.; Ulber, R.; Lang, S. Fucoidans and Fucoidanases—Focus on Techniques for Molecular Structure Elucidation and Modification of Marine Polysaccharides. Appl. Microbiol. Biotechnol. 2009, 82 (1), 1–11spa
dc.relation.referencesKadam, S. U.; Tiwari, B. K.; O’Donnell, C. P. Extraction, Structure and Biofunctional Activities of Laminarin from Brown Algae. Int. J. Food Sci. Technol. 2015, 50 (1), 24–31spa
dc.relation.referencesArnold, T. M.; Targett, N. M. Marine Tannins: The Importance of a Mechanistic Framework for Predicting Ecological Roles. J. Chem. Ecol. 2002, 16spa
dc.relation.referencesBringloe, T. T.; Starko, S.; Wade, R. M.; Vieira, C.; Kawai, H.; De Clerck, O.; Cock, J. M.; Coelho, S. M.; Destombe, C.; Valero, M.; Neiva, J.; Pearson, G. A.; Faugeron, S.; Serrão, E. A.; Verbruggen, H. Phylogeny and Evolution of the Brown Algae. Crit. Rev. Plant Sci. 2020, 39 (4), 281–321spa
dc.relation.referencesAraújo, R. M.; Assis, J.; Aguillar, R.; Airoldi, L.; Bárbara, I.; Bartsch, I.; Bekkby, T.; Christie, H.; Davoult, D.; Derrien-Courtel, S.; Fernandez, C.; Fredriksen, S.; Gevaert, F.; Gundersen, H.; Le Gal, A.; Lévêque, L.; Mieszkowska, N.; Norderhaug, K. M.; Oliveira, P.; Puente, A.; Rico, J. M.; Rinde, E.; Schubert, H.; Strain, E. M.; Valero, M.; Viard, F.; Sousa-Pinto, I. Status, Trends and Drivers of Kelp Forests in Europe: An Expert Assessment. Biodivers. Conserv. 2016, 25 (7), 1319–1348spa
dc.relation.referencesMerzouk, A.; Johnson, L. E. Kelp Distribution in the Northwest Atlantic Ocean under a Changing Climate. J. Exp. Mar. Biol. Ecol. 2011, 400 (1–2), 90–98spa
dc.relation.referencesSantelices, B. The Discovery of Kelp Forests in Deep-Water Habitats of Tropical Regions. Proc. Natl. Acad. Sci. 2007, 104 (49), 19163–19164spa
dc.relation.referencesTroncoso-Pantoja, C.; Aguirre-Céspedes, C.; Sotomayor-Castro, M.; Alarcón-Riveros, M. Durvillaea Antárctica: Revalorando Un Alimento Patrimonial. Rev. Chil. Nutr. 2019. 46(2) 215-216spa
dc.relation.referencesEngelen, A. H.; Åberg, P.; Olsen, J. L.; Stam, W. T.; Breeman, A. M. Effects of Wave Exposure and Depth on Biomass, Density and Fertility of the Fucoid Seaweed Sargassum Polyceratium (Phaeophyta, Sargassaceae). Eur. J. Phycol. 2005, 40 (2), 149–158spa
dc.relation.referencesStiger, V.; Deslandes, E.; Payri, C. E. Phenolic Contents of Two Brown Algae, Turbinaria ornata and Sargassum mangarevense on Tahiti (French Polynesia): Interspecific, Ontogenic and Spatio-Temporal Variations. Bot. Mar. 2004, 47 (5)spa
dc.relation.referencesAndrefouet, S.; Zubia, M.; Payri, C. Mapping and Biomass Estimation of the Invasive Brown Algae Turbinaria Ornata (Turner) J. Agardh and Sargassum mangarevense (Grunow) Setchell on Heterogeneous Tahitian Coral Reefs Using 4-Meter Resolution IKONOS Satellite Data. Coral Reefs 2004, 23 (1), 26–38.spa
dc.relation.referencesSmetacek, V.; Zingone, A. Green and Golden Seaweed Tides on the Rise. Nature 2013, 504 (7478), 84–88.spa
dc.relation.referencesSchell, J.; Goodwin, D.; Siuda, A. Recent Sargassum Inundation Events in the Caribbean: Shipboard Observations Reveal Dominance of a Previously Rare Form. Oceanography 2015, 28 (3), 8–10.spa
dc.relation.referencesMcLawrence, J.; Sealy, H.; Roberts, D. The Impacts and Challenges of the 2015 Sargassum Seaweed Invasion in the Caribbean. Int. J. Ecol. Environ. Sci. 2017, 43 (4), 309–317.spa
dc.relation.referencesMilledge, J. J.; Nielsen, B. V.; Bailey, D. High-Value Products from Macroalgae: The Potential Uses of the Invasive Brown Seaweed, Sargassum muticum. Rev. Environ. Sci. Biotechnol. 2016, 15 (1), 67–88.spa
dc.relation.referencesTronholm, A.; Sansón, M.; Afonso-Carrillo, J.; De Clerck, O. Distinctive Morphological Features, Life-Cycle Phases and Seasonal Variations in Subtropical Populations of Dictyota dichotoma (Dictyotales, Phaeophyceae). Bot. Mar. 2008, 51 (2), 132-144.spa
dc.relation.referencesTronholm, A.; Sansón, M.; Afonso-Carrillo, J.; Verbruggen, H.; De Clerck, O. Niche Partitioning And The Coexistence Of Two Cryptic Dictyota (Dictyotales, Phaeophyceae) Species From The Canary Islands. J. Phycol. 2010, 46 (6), 1075–1087.spa
dc.relation.referencesTronholm, A.; Steen, F.; Tyberghein, L.; Leliaert, F.; Verbruggen, H.; Antonia Ribera Siguan, M.; De Clerck, O. Species Delimitation, Taxonomy, And Biogeography Of Dictyota In Europe (Dictyotales, Phaeophyceae). J. Phycol. 2010, 46 (6), 1301–1321.spa
dc.relation.referencesTronholm, A.; Afonso-Carrillo, J.; Sansón, M.; Leliaert, F.; Fernández-García, C.; De Clerck, O. Taxonomy of the Dictyota ciliolata–crenulata Complex (Dictyotales, Phaeophyceae). Phycologia 2013, 52 (2), 171–181.spa
dc.relation.referencesBeach, K.; Walters, L.; Borgeas, H.; Smith, C.; Coyer, J.; Vroom, P. The Impact of Dictyota Spp. on Halimeda Populations of Conch Reef, Florida Keys. J. Exp. Mar. Biol. Ecol. 2003, 297 (2), 141–159.spa
dc.relation.referencesHeilbron, I. Some Aspects of Algal Chemistry. J. Chem. Soc. 1964, 74 (4), 79–89.spa
dc.relation.referencesMautner, H. The Chemistry of Brown Algae. Econ. Bot. 1954, 8 (2), 174–192.spa
dc.relation.referencesLin, T.-Y.; Hassid, W. Z. Pathway of Alginic Acid Synthesis in the Marine Brown Alga, Fucus gardneri Silva. J. Biol. Chem. 1966, 241 (22), 5284–5297.spa
dc.relation.referencesAnno, K.; Terahata, H.; Hayashi, Y.; Seno, N. Isolation and Purification of Fucoidin from Brown Seaweed Pelvetia wrightii. Agric. Biol. Chem. 1966, 30 (5), 495–499.spa
dc.relation.referencesSteinberg, P. D. Biogeographical Variation in Brown Algal Polyphenolics and Other Secondary Metabolites: Comparison between Temperate Australasia and North America. Oecologia 1989, 78 (3), 373–382.spa
dc.relation.referencesSteinberg, P. D. Seasonal Variation in the Relationship between Growth Rate and Phlorotannin Production in the Kelp Ecklonia radiata. Oecologia. 1995, 102 (2), 169–173.spa
dc.relation.referencesJennings, J. G.; Steinberg, P. D. Phlorotannins versus Other Factors Affecting Epiphyte Abundance on the Kelp Ecklonia radiata. Oecologia. 1997, 109 (3), 461–473.spa
dc.relation.referencesLüder, U. H.; Clayton, M. N. Induction of Phlorotannins in the Brown Macroalga Ecklonia radiata (Laminariales, Phaeophyta) in Response to Simulated Herbivory—the First Microscopic Study. Planta 2004, 218 (6), 928–937.spa
dc.relation.referencesVan Alstyne, K. L. Effects of Wounding by the Herbivorous Snails Littorina sitkana and L. scutulata (Mollusca) on Growth and Reproduction of the Intertidal Alga Fucus Distichus (Phaeophyta)1. J. Phycol. 1990, 26 (3), 412–416.spa
dc.relation.referencesHay, M. Marine Chemical Ecology: What’s Known and What’s next? J. Exp. Mar. Biol. Ecol. 1996, 200, 103–134.spa
dc.relation.referencesPaul, V. J.; Puglisi, M. P.; Ritson-Williams, R. Marine Chemical Ecology. Nat. Prod. Rep. 2006, 23 (2), 153.spa
dc.relation.referencesLittler, M. M.; Littler, D. S. The Nature of Macroalgae and Their Interactions on Reefs. Smithson. Contrib. Mar. Sci. 2013, 39.spa
dc.relation.referencesBarbosa, J. P.; Teixeira, V. L.; Pereira, R. C. A Dolabellane Diterpene from the Brown Alga Dictyota pfaffii as Chemical Defense against Herbivores. Bot. Mar. 2004, 47 (2)spa
dc.relation.referencesHay, M.; Duffy, J. E.; Fenical, W. Host-Plant Specialization Decreases Predation on a Marine Amphipod: An Herbivore in Plant’s Clothing. Ecology. 1990, 71 (2), 733–743.spa
dc.relation.referencesDuffy, J. E.; Hay, M. E. Seaweed Adaptations to Herbivory. BioScience. 1990. 40 (5), 368–375.spa
dc.relation.referencesHay, M.; Fenical, W.; Gustafson, K. Chemical Defense Against Diverse Coral-Reef Herbivores. Ecology. 1987, 68 (6), 1591–1591.spa
dc.relation.referencesRasher, D. B.; Stout, E. P.; Engel, S.; Kubanek, J.; Hay, M. E. Macroalgal Terpenes Function as Allelopathic Agents against Reef Corals. Proc. Natl. Acad. Sci. 2011, 108 (43), 17726–17731.spa
dc.relation.referencesBox, S.; Mumby, P. Effect of Macroalgal Competition on Growth and Survival of Juvenile Caribbean Corals. Mar. Ecol. Prog. Ser. 2007, 342, 139–149.spa
dc.relation.referencesKuffner, I.; Walters, L.; Becerro, M.; Paul, V.; Ritson-Williams, R.; Beach, K. Inhibition of Coral Recruitment by Macroalgae and Cyanobacteria. Mar. Ecol. Prog. Ser. 2006, 323, 107–117.spa
dc.relation.referencesChen, J.; Li, H.; Zhao, Z.; Xia, X.; Li, B.; Zhang, J.; Yan, X. Diterpenes from the Marine Algae of the Genus Dictyota. Mar. Drugs. 2018, 16 (5), 159.spa
dc.relation.referencesRushdi, M. I.; Abdel-Rahman, I. A. M.; Saber, H.; Attia, E. Z.; Madkour, H. A.; Abdelmohsen, U. R. A Review on the Pharmacological Potential of the Genus Padina. South Afr. J. Bot. 2021, 141, 37–48.spa
dc.relation.referencesTeixeira, V. L.; Kelecom, A. A Chemotaxonomic Study of Diterpenes from Marine Brown Algae of the Genus Dictyota. Sci. Total Environ. 1988, 75 (2–3), 271–283.spa
dc.relation.referencesPardo-Vargas, A.; de Barcelos Oliveira, I.; Stephens, P.; Cirne-Santos, C.; de Palmer Paixão, I.; Ramos, F.; Jiménez, C.; Rodríguez, J.; Resende, J.; Teixeira, V.; Castellanos, L. Dolabelladienols A–C, New Diterpenes Isolated from Brazilian Brown Alga Dictyota pfaffii. Mar. Drugs. 2014, 12 (7), 4247–4259.spa
dc.relation.referencesMenezes, M.; Bicudo, C. E. M.; Moura, C. W. N.; Alves, A. M.; Santos, A. A.; Pedrini, A. de G.; Araújo, A.; Tucci, A.; Fajar, A.; Malone, C.; Kano, C. H.; Sant’Anna, C. L.; Branco, C. Z.; Odebrecht, C.; Peres, C. K.; Neuhaus, E. B.; Eskinazi-Leça, E.; Aquino, E.; Nauer, F.; Santos, G. N.; Amado Filho, G. M.; Lyra, G. M.; Borges, G. C. P.; Costa, I. O.; Nogueira, I. de S.; Oliveira, I. B.; Paula, Joel. C. de; Nunes, J. M. de C.; Lima, J. C.; Santos, K. R. S.; Ferreira, L. C.; Gestinari, L. M. S.; Cardoso, L. S.; Figueiredo, M. A. O.; Silva, M. H.; Barreto, M. B. B. B.; Henriques, M. C. O.; Cunha, M. da G. G. S.; Bandeira-Pedrosa, M. E.; Oliveira-Carvalho, M. F.; Széchy, M. T. M.; Azevedo, M. T. P.; Oliveira, M. C. de; Cabezudo, M. M.; Santiago, M. F.; Bergesh, M.; Fujii, M. T.; Bueno, N. C.; Necchi Jr., O.; Jesus, P. B.; Bahia, R. G.; Khader, S.; Alves-da-Silva, S. M.; Guimarães, S. M. P. B.; Pereira, S. M. B.; Caires, T. A.; Meurer, T.; Cassano, V.; Werner, V. R.; Gama Jr., W. A. da; Silva, W. J. da. Update of the Brazilian Floristic List of Algae and Cyanobacteria. Rodriguésia. 2015, 66 (4), 1047–1062.spa
dc.relation.referencesDe-Paula, J. C.; Pedrini, A. de G.; Pinheiro, M. D.; Pereira, R. C.; Teixeira, V. L. Chemical Similarity between the Brown Algae Dictyota Cervicornis and D. Pardalis (Dictyotales, Phaeophyta). Biochem. Syst. Ecol. 2001, 29 (4), 425–427.spa
dc.relation.referencesPereira, H. de S.; Leão-Ferreira, L. R.; Moussatché, N.; Teixeira, V. L.; Cavalcanti, D. N.; da Costa, L. J.; Diaz, R.; Frugulhetti, I. C. Effects of Diterpenes Isolated from the Brazilian Marine Alga Dictyota menstrualis on HIV-1 Reverse Transcriptase. Planta Med. 2005, 71 (11), 1019–1024.spa
dc.relation.referencesDe-Paula, J.; Bueno, L.; Cavalcanti, D.; Yoneshigue-Valentin, Y.; Teixeira, V. Diterpenes from the Brown Alga Dictyota crenulata. Molecules. 2008, 13 (6), 1253–1262.spa
dc.relation.referencesCavalcanti, D. N.; de Oliveira, M.-A. R.; De-Paula, J. C.; Barbosa, L. S.; Fogel, T.; Pinto, M. A.; de Palmer Paixão, I. C. N.; Teixeira, V. L. Variability of a Diterpene with Potential Anti-HIV Activity Isolated from the Brazilian Brown Alga. Dictyota menstrualis. J. Appl. Phycol. 2011, 23 (5), 873–876.spa
dc.relation.referencesSimas, D. L. R.; Kaiser, C. R.; Gestinari, L. M.; Duarte, H. M.; de Paula, J. C.; Soares, A. R. Diterpenes from the Brown Seaweed Dictyota caribaea (Dictyotaceae, Phaeophyceae): The Ecological and Taxonomic Significance. Biochem. Syst. Ecol. 2014, 52, 33–37.spa
dc.relation.referencesGarrido, V.; Barros, C.; Melchiades, V. A.; Fonseca, R. R.; Pinheiro, S.; Ocampo, P.; Teixeira, V. L.; Cavalcanti, D. N.; Giongo, V.; Ratcliffe, N. A.; Teixeira, G.; Paixão, I. C. N. P. Subchronic Toxicity and Anti-HSV-1 Activity in Experimental Animal of Dolabelladienetriol from the Seaweed, Dictyota pfaffii. Regul. Toxicol. Pharmacol. 2017, 86, 193–198.spa
dc.relation.referencesAnk, G.; da Gama, B. A. P.; Pereira, R. C. Polyphenols from Stypopodium zonale (Phaeophyceae): Intrapopulational Variation, Induction by Simulated Herbivory, and Epibiosis Effects. Aquat. Bot. 2013, 111, 125–129.spa
dc.relation.referencesSoares, A. R.; Duarte, H. M.; Tinnoco, L. W.; Pereira, R. C.; Teixeira, V. L. Intraspecific Variation of Meroditerpenoids in the Brown Alga Stypopodium zonale Guiding the Isolation of New Compounds. Rev. Bras. Farmacogn. 2015, 25 (6), 627–633.spa
dc.relation.referencesDiaz-Pulido, G.; Díaz-Ruíz, M. Diversity of Benthic Marine Algae of the Colombian Atlantic. Biota Colomb. 2003, 4 (2), 203–246.spa
dc.relation.referencesRincón- Díaz, M. N.; Ramos, F. Macroalgas Marinas El Universo Productivo de La Reserva de Biosfera Seaflower. En Biodiversidad del mar de los siete colores; 84; Serie de Publicaciones Generales del INVEMAR: Santa Marta, 2016; p 229.spa
dc.relation.referencesEchavarria, B.; Franco, A.; Martinez, M. Evaluación De La Actividad Antioxidante Y Determinación Del Contenido De Compuestos Fenólicos En Extractos De Macroalgas Del Caribe Colombiano. Vitae. 2009, 16 (1), 126–131.spa
dc.relation.referencesPardo, A. Bioprospección de Productos Naturales Marinos de Organismos Bentónicos Del Litoral Brasileño y Caribe Colombiano- Fase I Tribu Dictyoteae. Título magister en ciencias, Universidad Nacional de Colombia, Bogota, 2013.spa
dc.relation.referencesRubiano, P. Estudio de Diterpenos Marinos de Algas Del Género Dictyota Del Caribe Colombiano. Tesis Maestria, Universidad Nacional de Colombia, Bogota, 2018spa
dc.relation.referencesAbril-Howard, A.; Bolaños, N.; Lasso, I.; Gómez, I.; Ward, V. Actualización Del Conocimiento de Los Ecosistemas Marinos En La Reserva de Biósfera Seaflower, Con Énfasis En Las Islas de San Andrés y Providencia. In Atlas de la Reserva de Biósfera Seaflower. Archipiélago de San Andrés, Providencia y Santa Catalina; 28; Serie de Publicaciones Generales del INVEMAR: Santa Marta, 2012; p 180.spa
dc.relation.referencesInforme Del Estado de Los Ambientes y Recursos Marinos y Costeros En Colombia 2021; Garay, J., Series Ed.; Serie de Publicaciones Periódicas; INVEMAR: Santa Marta, 2022; p 254.spa
dc.relation.referencesLozano-Cortés, D. F.; Zapata, F. A. Abundance and Composition of Juvenile Scleractinian Corals on a Fringing Reef (Little Reef) off San Andres Island, Colombian Caribbean. Mar. Biol. Res. 2015, 11 (3), 304–312.spa
dc.relation.referencesHughes, T. P. Community Structure and Diversity of Coral Reefs: The Role of History. Ecology 1989, 70 (1), 275–279spa
dc.relation.referencesBourne, D. G.; Munn, C. B. Diversity of Bacteria Associated with the Coral Pocillopora Damicornis from the Great Barrier Reef. Environ. Microbiol. 2005, 7 (8), 1162–1174.spa
dc.relation.referencesPandolfi, J. Coral Community Dynamics at Multiple Scales. Coral Reefs 2002, 21 (1), 13–23.spa
dc.relation.referencesCole, A. J.; Pratchett, M. S.; Jones, G. P. Diversity and Functional Importance of Coral-Feeding Fishes on Tropical Coral Reefs. Fish. 2008, 9 (3), 286–307.spa
dc.relation.referencesBirrell, C.; Mccook, L.; Willis, B.; Diaz-Pulido, G. Effects Of Benthic Algae On The Replenishment Of Corals And The Implications For The Resilience Of Coral Reefs. In Oceanography and Marine Biology; Gibson, R., Atkinson, R., Gordon, J., Eds.; CRC Press, 2008; pp 25–63spa
dc.relation.referencesRodríguez, K. M. S.; Zapata, F. A.; Mejia-Landino, L. M. Diversity And Distribution Of Fishes Along The Depth Gradient Of A Coral Reef Wall At San Andrés Island, Colombian Caribbean. Boletin Investig. Mar. Costeras. 2016, 45 (1), 15–39.spa
dc.relation.referencesBaine, M.; Howard, M.; Kerr, S.; Edgar, G.; Toral, V. Coastal and Marine Resource Management in the Galapagos Islands and the Archipelago of San Andres: Issues, Problems and Opportunities. Ocean Coast. Manag. 2007, 50 (3–4), 148–173.spa
dc.relation.referencesKleypas, J. A.; Mcmanus, J. W.; Meñez, L. A. B. Environmental Limits to Coral Reef Development: Where Do We Draw the Line? Am. Zool. 1999, 39 (1), 146–159.spa
dc.relation.referencesSzmant, A. M. Nutrient Enrichment on Coral Reefs: Is It a Major Cause of Coral Reef Decline? Estuaries. 2002, 25 (4), 743–766.spa
dc.relation.referencesEdmunds, P. J.; Carpenter, R. C. Recovery of Diadema Antillarum Reduces Macroalgal Cover and Increases Abundance of Juvenile Corals on a Caribbean Reef. Proc. Natl. Acad. Sci. 2001, 98 (9), 5067–5071.spa
dc.relation.referencesLessios, H. A. The Great Diadema antillarum Die-Off: 30 Years Later. Annu. Rev. Mar. Sci. 2016, 8 (1), 267–283.spa
dc.relation.referencesPuyana, M. The Fate of Corals: Will They Overcome Competition with Algae and Cyanobacteria in a Changing Environment? In Corals in a Changing World; Beltran, C. D., Camacho, E. T., Eds.; InTech, 2018. 122-142spa
dc.relation.referencesBeach, K.; Walters, L.; Borgeas, H.; Smith, C.; Coyer, J.; Vroom, P. The Impact of Dictyota spp. on Halimeda Populations of Conch Reef, Florida Keys. J. Exp. Mar. Biol. Ecol. 2003, 297 (2), 141–159.spa
dc.relation.referencesMcManus, J. Coral Reef Fishing and Coral-Algal Phase Shifts: Implications for Global Reef Status. ICES J. Mar. Sci. 2000, 57 (3), 572–578.spa
dc.relation.referencesMcManus, J. W.; Polsenberg, J. F. Coral–Algal Phase Shifts on Coral Reefs: Ecological and Environmental Aspects. Prog. Oceanogr. 2004, 60 (2–4), 263–279.spa
dc.relation.referencesZea, S.; Geister, J.; Garzón-Ferreira, J.; Diaz, J. Biotic Changes In The Reef Complex Of San Andres Island (Southeastern Caribbean Sea, Columbia) Occurring Over Nearly Three Decades. Atoll Res. Bull. 1998, 456, 1–30.spa
dc.relation.referencesWoesik, R.; Ripple, K.; Miller, S. L. Macroalgae Reduces Survival of Nursery-Reared Acropora Corals in the Florida Reef Tract: Macroalgae Suppresses Coral Survival. Restor. Ecol. 2018, 26 (3), 563–569.spa
dc.relation.referencesAlbis-Salas, M. R.; Gavio, B. Notes on Marine Algae in the International Biosphere Reserve Seaflower, Caribbean Colombian I: New Records of Macroalgal Epiphytes on the Seagrass Thalassia testudinum. Bot. Mar. 2011, 54 (6).spa
dc.relation.referencesGavio, B.; Reyes-Gómez, V. P.; Wynne, M. J. Crouania Pumila Sp. Nov. (Callithamniaceae: Rhodophyta), a New Species of Marine Red Algae from the Seaflower International Biosphere Reserve, Caribbean Colombia. Rev Biol Trop. 2013, 61 (3), 1015–1023.spa
dc.relation.referencesRincón-Díaz, M. N.; Gavio, B.; Santos-Martínez, A. Occurrence Of Tetrasporangia In Ceramium bisporum (Ceramiales, Rhodophyta). Acta Biológica Colomb. 2014, 19 (2), 315.spa
dc.relation.referencesRincón-Díaz, M. N.; Gavio, B.; Wynne, M. J.; Santos-Martínez, A. Notes on Marine Algae in the International Biosphere Reserve Seaflower, Caribbean Colombia, VII: Additions to the Benthic Flora of San Andrés Island. Caldasia. 2018, 40 (1), 97–111.spa
dc.relation.referencesReyes-Gómez, V. P.; Velásquez Pomar, H.; Gavio, B. Notes on the Marine Algae of the International Biosphere Reserve Seaflower, Caribbean Colombia VIII: New Records of Red Algae (Rhodophyta) from San Andres, Old Providence, and Saint Cataline, Colombia. Acta Bot. Mex. 2021spa
dc.relation.referencesOrtiz, J. F.; Gavio, B. Notes on the Marine Algae of the International Biosphere Reserve Seaflower, Caribbean Colombia II: Diversity of Drift Algae in San Andres Island, Caribbean Colombia. Caribb. J. Sci. 2012, 46 (2–3), 313–321.spa
dc.relation.referencesGavio, B.; Rincón-Díaz, M. N.; Santos-Martínez, A. Massive Quantities Of Pelagic Sargassum On The Shores Of San Andres Island, Southwestern Caribbean. Acta Biológica Colomb. 2015, 20 (1), 3.spa
dc.relation.referencesVega Sequeda, J.; Díaz Sánchez, C. M.; Gómez Campo, K.; López Londoño, T.; Díaz Ruiz, M.; Gómez-López, D. I. Biodiversidad Marina En Bajo Nuevo, Bajo Alicia Y Banco Serranilla, Reserva De Biosfera Seaflower. Bull. Mar. Coast. Res. 2015, 44 (1).spa
dc.relation.referencesGavio, B.; Cifuentes Ossa, M. A.; Wynne, M. J. Notes On The Marine Algae Of The International Biosphere Reserve Seaflower, Caribbean Colombia V: First Study Of The Algal Flora Of Quitasueño Bank. Bull. Mar. Coast. Res. 2015, 44 (1).spa
dc.relation.referencesBula-Meyer, G. Las Macroalgas Marinas En La Agronomía Y El Uso Potencial Del Sargassum Flotante En La Producción De Fertilizantes En El Archipiélago De San Andrés Y Providencia, Colombia. Rev. Intropica. 2004, 1, 91–103.spa
dc.relation.referencesLittler, D. S.; Littler, M. M. Caribbean Reef Plants. OffShore Graphics. Washington DC, 2000.spa
dc.relation.referencesGuiry, M. AlgaeBase: Listing the World’s Algae. AlgaeBase. https://www.algaebase.org/ (accessed 2022-10-05).spa
dc.relation.referencesMonroy, J.; Pico, S.; Dagua, C.; Herrera, P. Boletín Meteomarino Mensual Del Caribe Colombiano No.73/Enero de 2019; Boletín Meteomarino Mensual del Caribe Colombiano; 73; CIOH: Cartagena, 2019; p 50.spa
dc.relation.referencesMonroy, J.; Avellaneda, N.; Dagua, C.; Herera, P. Boletín Meteomarino Mensual Del Caribe Colombiano No.65/ Mayo de 2018; Boletín Meteomarino Mensual del Caribe Colombiano; 65; CIOH: Cartagena, 2018; p 53.spa
dc.relation.referencesMoreno, M.; Pico, S.; Dagua, C.; Herrera, P. Boletín Meteomarino Mensual Del Caribe Colombiano No.82 / Octubre de 2019; Boletín Meteomarino Mensual del Caribe Colombiano; 82; CIOH: Cartagena, 2019; p 48.spa
dc.relation.referencesMoreno, M.; Pico, S.; Dagua, C.; Herrera, P. Boletín Meteomarino Mensual Del Caribe Colombiano No.77/ Mayo de 2019; Boletín Meteomarino Mensual del Caribe Colombiano; 77; CIOH: Cartagena, 2019; p 53.spa
dc.relation.referencesMoreno, M.; Pico, S.; Dagua, C.; Herrera, P. Boletín Meteomarino Mensual Del Caribe Colombiano No.97 / Enero de 2021; Boletín Meteomarino Mensual del Caribe Colombiano; 97; CIOH: Cartagena, 2021; p 47.spa
dc.relation.referencesInforme Del Estado de Los Ambientes y Recursos Marinos y Costeros En Colombia 2013; Garay, J., Series Ed.; Serie de Publicaciones Periódicas; INVEMAR: Santa Marta, 2014; p 192.spa
dc.relation.referencesInforme Del Estado de Los Ambientes y Recursos Marinos y Costeros En Colombia 2017; Garay, J., Series Ed.; Serie de Publicaciones Periódicas; INVEMAR: Santa Marta, 2018; p 180.spa
dc.relation.referencesDiaz-Pulido, G.; Díaz-Ruíz, M. Diversity of Benthic Marine Algae of the Colombian Atlantic. Biota Colomb. 2003, 4 (2), 203–246.spa
dc.relation.referencesDe-Paula, J. C.; Cassano, V.; Yoneshigue-Valentin, Y.; Teixeira, V. L. Diterpenes from the Brazilian Brown Alga Dictyota crispata (Dictyotaceae, Phaeophyta). Nat. Prod. Commun. 2007, 2 (2), 135–137.spa
dc.relation.referencesHay, M.; Duffy, J.; Fenical, W.; Gustafson, K. Chemical Defense in the Seaweed Dictyopteris delicatula: Differential Effects against Reef Fishes and Amphipods. Mar. Ecol. Prog. Ser. 1988, 48, 185–192.spa
dc.relation.referencesWright, A. D.; Coll, J. C.; Price, I. R. Tropical Marine Algae, VII. The Chemical Composition of Marine Algae from North Queensland Waters. J. Nat. Prod. 1990, 53 (4), 845–861.spa
dc.relation.referencesMarques, C. T.; Azevedo, T. C. G. de; Nascimento, M. S.; Medeiros, V. P.; Alves, L. G.; Benevides, N. M. B.; Rocha, H. A. O.; Leite, E. L. Sulfated Fucans Extracted from Algae Padina gymnospora Have Anti-Inflammatory Effect. Rev. Bras. Farmacogn. 2012, 22 (1), 115–122.spa
dc.relation.referencesSilva, T. M. A.; Alves, L. G.; Queiroz, K. C. S. de; Santos, M. G. L.; Marques, C. T.; Chavante, S. F.; Rocha, H. A. O.; Leite, E. L. Partial Characterization and Anticoagulant Activity of a Heterofucan from the Brown Seaweed Padina gymnospora. Braz. J. Med. Biol. Res. 2005, 38 (4), 523–533.spa
dc.relation.referencesSethupathy, S.; Shanmuganathan, B.; Kasi, P. D.; Karutha Pandian, S. Alpha-Bisabolol from Brown Macroalga Padina gymnospora Mitigates Biofilm Formation and Quorum Sensing Controlled Virulence Factor Production in Serratia Marcescens. J. Appl. Phycol. 2016, 28 (3), 1987–1996.spa
dc.relation.referencesShanmuganathan, B.; Sathya, S.; Balasubramaniam, B.; Balamurugan, K.; Devi, K. P. Amyloid-β Induced Neuropathological Actions Are Suppressed by Padina gymnospora (Phaeophyceae) and Its Active Constituent α-Bisabolol in Neuro2a Cells and Transgenic Caenorhabditis Elegans Alzheimer’s Model. Nitric Oxide. 2019, 91, 52–66.spa
dc.relation.referencesGerwick, W.; Fenical, W.; Fritsch, N.; Clardy, J. Stypotriol And Stypoldione; Ichthyotoxins Of Mixed Biogenesis. Tetrahedron Lett. 1979, 2, 145–148.spa
dc.relation.referencesGerwick, W.; Fenical, W. Ichthyotoxic and Cytotoxic Metabolites of the Tropical Brown Alga Stypopodium zonale (Lamouroux) Papenfuss. J. Org. Chem. 1981, 46 (1), 22–27.spa
dc.relation.referencesLittler, M. M.; Taylor, P. R.; Littler, D. S. Algal Resistance to Herbivory on a Caribbean Barrier Reef. Coral Reefs. 1983, 2 (2), 111–118.spa
dc.relation.referencesJacobs, R. S.; Culver, P.; Langdon, R.; O’Brien, T.; White, S. Some Pharmacological Observations on Marine Natural Products. Tetrahedron. 1985, 41 (6), 981–984.spa
dc.relation.referencesHay, M.; Fenical, W.; Gustafson, K. Chemical Defense Against Diverse Coral-Reef Herbivores. Ecology. 1987, 68 (6), 1591–1591.spa
dc.relation.referencesPereira, R. C.; Soares, A. R.; Teixeira, V. L.; Villaça, R.; Gama, B. A. P. da. Variation in Chemical Defenses against Herbivory in Southwestern Atlantic Stypopodium zonale (Phaeophyta). Bot. Mar. 2004, 47 (3).spa
dc.relation.referencesWhite, S.; Jacobs, R. Effect of Stypoldione on Cell Cycle Progression, DNA and Protein Synthesis, and Cell Division in Cultured Sea Urchin Embryos. Mol. Pharmacol. 1983, 24 (3), 500–508.spa
dc.relation.referencesO’Brien, E.; White, S.; Jacob, R.; Boder, G.; Wilson, l. Pharmacological Properties of a Marine Natural Product, Stypoldione, Obtained from the Brown Alga Stypopodium Zonale; Springer: Holanda. 1984; pp 141–145.spa
dc.relation.referencesWalter, L. O.; Maioral, M. F.; Silva, L. O.; Speer, D. B.; Campbell, S. C.; Gallimore, W.; Falkenberg, M. B.; Santos‐Silva, M. C. Involvement of the NF‐ΚB and PI3K /Akt/ MTOR Pathways in Cell Death Triggered by Stypoldione, an O‐quinone Isolated from the Brown Algae Stypopodium zonale. Environ. Toxicol. 2022, 37 (6), 1297–1309.spa
dc.relation.referencesWessels, M.; König, G. M.; Wright, A. D. A New Tyrosine Kinase Inhibitor from the Marine Brown Alga Stypopodium zonale. J. Nat. Prod. 1999, 62 (6), 927–930.spa
dc.relation.referencesMendes, G.; Soares, A. R.; Sigiliano, L.; Machado, F.; Kaiser, C.; Romeiro, N.; Gestinari, L.; Santos, N.; Romanos, M. T. V. In Vitro Anti-HMPV Activity of Meroditerpenoids from Marine Alga Stypopodium zonale (Dictyotales). Molecules. 2011, 16 (10), 8437–8450.spa
dc.relation.referencesSoares, D.; Szlachta, M.; Teixeira, V.; Soares, A.; Saraiva, E. The Brown Alga Stypopodium zonale (Dictyotaceae): A Potential Source of Anti-Leishmania Drugs. Mar. Drugs. 2016, 14, 163.spa
dc.relation.referencesPenicooke, N.; Walford, K.; Badal, S.; Delgoda, R.; Williams, L. A. D.; Joseph-Nathan, P.; Gordillo-Román, B.; Gallimore, W. Antiproliferative Activity and Absolute Configuration of Zonaquinone Acetate from the Jamaican Alga Stypopodium zonale. Phytochemistry. 2013, 87, 96–101.spa
dc.relation.referencesEngelen, A. H.; Åberg, P.; Olsen, J. L.; Stam, W. T.; Breeman, A. M. Effects of Wave Exposure and Depth on Biomass, Density and Fertility of the Fucoid Seaweed Sargassum polyceratium (Phaeophyta, Sargassaceae). Eur. J. Phycol. 2005, 40 (2), 149–158.spa
dc.relation.referencesEngelen, a; Olsen, J.; Breeman, A.; Stam, W. Genetic Differentiation in Sargassum polyceratium (Fucales: Phaeophyceae) around the Island of Curaçao (Netherlands Antilles). Mar. Biol. 2001, 139 (2), 267–277.spa
dc.relation.referencesGonzález-Nieto, D.; Oliveira, M. C.; Núñez Resendiz, M. L.; Dreckmann, K. M.; Mateo-Cid, L. E.; Sentíes, A. Molecular Assessment of the Genus Sargassum (Fucales, Phaeophyceae) from the Mexican Coasts of the Gulf of Mexico and Caribbean, with the Description of S. Xochitlae Sp. Nov. Phytotaxa. 2020, 461 (4), 254–274.spa
dc.relation.referencesBrodie, J.; Norris, K. Life History and Morphology of Liagora Afr. ceranoides (Liagoraceae, Rhodophyta) from the Florida Keys. Phycologia. 1992, 31 (5), 419–430.spa
dc.relation.referencesLin, S.-M.; Huisman, J. M.; Payri, C. Characterization of Liagora ceranoides (Liagoraceae, Rhodophyta) on the Basis of Rbc L Sequence Analyses and Carposporophyte Development, Including Yoshizakia Indopacifica Gen. et Sp. Nov. from the Indo-Pacific Region. Phycologia. 2013, 52 (2), 161–170spa
dc.relation.referencesPasdaran, A.; Hamedi, N. Antibacterial and Insecticidal Activity of Volatile Compounds of Three Algae Species of Oman Sea. Int. J. Second. Metab. 2016, 3 (2), 66–73.spa
dc.relation.referencesLiu, X.; Locasale, J. W. Metabolomics: A Primer. Trends Biochem. Sci. 2017, 42 (4), 274–284.spa
dc.relation.referencesSchripsema, J.; Dagnino, D. Metabolomics: Experimental Design, Methodology, and Data Analysis. In Encyclopedia of Analytical Chemistry; Meyers, R. A., Ed.; Wiley, 2019; pp 1–22.spa
dc.relation.referencesKorman, A.; Oh, A.; Raskind, A.; Banks, D. Statistical Methods in Metabolomics. In Evolutionary Genomics: Statistical and Computational Methods, Volume 2; Anisimova, M., Ed.; Humana Press: Totowa, NJ, 2012; pp 381–413.spa
dc.relation.referencesIvanišević, J.; Thomas, O. P.; Lejeusne, C.; Chevaldonné, P.; Pérez, T. Metabolic Fingerprinting as an Indicator of Biodiversity: Towards Understanding Inter-Specific Relationships among Homoscleromorpha Sponges. Metabolomics. 2011, 7 (2), 289–304.spa
dc.relation.referencesJaramillo, K. B.; Reverter, M.; Guillen, P. O.; McCormack, G.; Rodriguez, J.; Sinniger, F.; Thomas, O. P. Assessing the Zoantharian Diversity of the Tropical Eastern Pacific through an Integrative Approach. Sci. Rep. 2018, 8 (1), 7138.spa
dc.relation.referencesMooney, B. D.; Nichols, P. D.; de Salas, M. F.; Hallegraeff, G. M. Lipid, Fatty Acid, And Sterol Composition Of Eight Species Of Kareniaceae (Dinophyta): Chemotaxonomy And Putative Lipid Phycotoxins. J. Phycol. 2007, 43 (1), 101–111.spa
dc.relation.referencesMolina, S. L.; Forero, A. M.; Ayala, F. I.; Puyana, M.; Zea, S.; Castellanos, L.; Muñoz, D.; Arboleda, G.; Sandoval-Hernández, A. G.; Ramos, F. A. Metabolic Profiling of the Soft Coral Erythropodium caribaeorum (Alcyonacea: Anthothelidae) from the Colombian Caribbean Reveals Different Chemotypes. Mar. Drugs. 2019, 18 (1), 4.spa
dc.relation.referencesFelline, S.; Del Coco, L.; Kaleb, S.; Guarnieri, G.; Fraschetti, S.; Terlizzi, A.; Fanizzi, F. P.; Falace, A. The Response of the Algae Fucus virsoides (Fucales, Ochrophyta) to Roundup® Solution Exposure: A Metabolomics Approach. Environ. Pollut. 2019, 254spa
dc.relation.referencesGhallab, D. S.; Shawky, E.; Ibrahim, R. S.; Mohyeldin, M. M. Comprehensive Metabolomics Unveil the Discriminatory Metabolites of Some Mediterranean Sea Marine Algae in Relation to Their Cytotoxic Activities. Sci. Rep. 2022, 12 (1), 8094.spa
dc.relation.referencesBundy, J. G.; Davey, M. P.; Viant, M. R. Environmental Metabolomics: A Critical Review and Future Perspectives. Metabolomics. 2009, 5 (1), 3–21.spa
dc.relation.referencesNylund, G. M.; Weinberger, F.; Rempt, M.; Pohnert, G. Metabolomic Assessment of Induced and Activated Chemical Defence in the Invasive Red Alga Gracilaria vermiculophylla. PLoS ONE. 2011, 6 (12).spa
dc.relation.referencesGaubert, J.; Greff, S.; Thomas, O. P.; Payri, C. E. Metabolomic Variability of Four Macroalgal Species of the Genus Lobophora Using Diverse Approaches. Phytochemistry. 2019, 162, 165–172.spa
dc.relation.referencesGaubert, J.; Payri, C. E.; Vieira, C.; Solanki, H.; Thomas, O. P. High Metabolic Variation for Seaweeds in Response to Environmental Changes: A Case Study of the Brown Algae Lobophora in Coral Reefs. Sci. Rep. 2019, 9 (1), 993.spa
dc.relation.referencesEchavarria, B.; Franco, A.; Martinez, M. Evaluación De La Actividad Antioxidante Y Determinación Del Contenido De Compuestos Fenólicos En Extractos De Macroalgas Del Caribe Colombiano. Vitae. 2009, 16 (1), 126–131.spa
dc.relation.referencesPardo, A. Bioprospección de Productos Naturales Marinos de Organismos Bentónicos Del Litoral Brasileño y Caribe Colombiano- Fase I Tribu Dictyoteae. Título magister en ciencias, Universidad Nacional de Colombia, Bogota, 2013.spa
dc.relation.referencesPardo-Vargas, A.; de Barcelos Oliveira, I.; Stephens, P.; Cirne-Santos, C.; de Palmer Paixão, I.; Ramos, F.; Jiménez, C.; Rodríguez, J.; Resende, J.; Teixeira, V.; Castellanos, L. Dolabelladienols A–C, New Diterpenes Isolated from Brazilian Brown Alga Dictyota pfaffii. Mar. Drugs 2014, 12 (7), 4247–4259.spa
dc.relation.referencesRestrepo, N. Extracción, Purificación y Análisis Del Contenido de Fucoxantina En Algas Pardas Del Caribe Colombiano. Tesis Biologo Marino, Universidad Jorge Tadeo Lozano, Bogota, 2015.spa
dc.relation.referencesRubiano, P. Estudio de Diterpenos Marinos de Algas Del Género Dictyota Del Caribe Colombiano. Tesis Maestria, Universidad Nacional de Colombia, Bogota, 2017.spa
dc.relation.referencesRubiano-Buitrago, P.; Duque, F.; Puyana, M.; Ramos, F. A.; Castellanos, L. Bacterial Biofilm Inhibitor Diterpenes from Dictyota pinnatifida Collected from the Colombian Caribbean. Phytochem. Lett. 2019, 30, 74–80.spa
dc.relation.referencesSiamopoulou, P.; Bimplakis, A.; Iliopoulou, D.; Vagias, C.; Cos, P.; Vanden Berghe, D.; Roussis, V. Diterpenes from the Brown Algae Dictyota dichotoma and Dictyota linearis. Phytochemistry. 2004, 65 (14), 2025–2030.spa
dc.relation.referencesGerwick, W.; Fenical, W.; Fritsch, N.; Clardy, J. Stypotriol And Stypoldione; Ichthyotoxins Of Mixed Biogenesis. Tetrahedron Lett. 1979, 2, 145–148.spa
dc.relation.referencesGerwick, W.; Fenical, W. Ichthyotoxic and Cytotoxic Metabolites of the Tropical Brown Alga Stypopodium zonale (Lamouroux) Papenfuss. J. Org. Chem. 1981, 46 (1), 22–27.spa
dc.relation.referencesGerwick, W. Chemical Variation in the Tropical Seaweed Stypopodium zonale (Dictyotaceae). Phytochemistry. 1985, 24 (6), 1279–1283.spa
dc.relation.referencesDe-Paula, J. C.; Cassano, V.; Yoneshigue-Valentin, Y.; Teixeira, V. L. Diterpenes from the Brazilian Brown Alga Dictyota crispata (Dictyotaceae, Phaeophyta). Nat. Prod. Commun. 2007, 2 (2), 135–137.spa
dc.relation.referencesBianco, É. M.; Teixeira, V. L.; Pereira, R. C. Chemical Defenses of the Tropical Marine Seaweed Canistrocarpus cervicornis against Herbivory by Sea Urchin. Braz. J. Oceanogr. 2010, 58 (3), 213–218.spa
dc.relation.referencesDorta, E.; Dı́az-Marrero, A. R.; Cueto, M.; Darias, J. On the Relative Stereochemistry of Atomaric Acid and Related Compounds. Tetrahedron. 2003, 59 (12), 2059–2062.spa
dc.relation.referencesSoares, A. R.; Duarte, H. M.; Tinnoco, L. W.; Pereira, R. C.; Teixeira, V. L. Intraspecific Variation of Meroditerpenoids in the Brown Alga Stypopodium zonale Guiding the Isolation of New Compounds. Rev. Bras. Farmacogn. 2015, 25 (6), 627–633spa
dc.relation.referencesFreitas, O. do S. P.; de Oliveira, A. S.; De-Paula, J. C.; Pereira, R. C.; Cavalcanti, D. N.; Teixeira, V. L. Chemical Variation in the Diterpenes from the Brazilian Brown Alga Dictyota mertensii (Dictyotaceae, Phaeophyta). Nat. Prod. Commun. 2007, 2 (1),spa
dc.relation.referencesBianco, É. M.; Martins Francisco, T.; Basílio Pinheiro, C.; Bagueira de Vasconcellos Azeredo, R.; Laneuville Teixeira, V.; Crespo Pereira, R. 10 β -Acetoxy-8 α ,9 α -Epoxy-14 β -Hydroxy-7-Oxodolastane - A New Diterpene Isolated from the Brazilian Brown Macroalga Canistrocarpus cervicornis. Helv. Chim. Acta. 2015, 98 (6), 785–794.spa
dc.relation.referencesBogaert, K. A.; Delva, S.; De Clerck, O. Concise Review of the Genus Dictyota J.V. Lamouroux. J. Appl. Phycol. 2020, 32 (3), 1521–1543.spa
dc.relation.referencesPenicooke, N.; Walford, K.; Badal, S.; Delgoda, R.; Williams, L. A. D.; Joseph-Nathan, P.; Gordillo-Román, B.; Gallimore, W. Antiproliferative Activity and Absolute Configuration of Zonaquinone Acetate from the Jamaican Alga Stypopodium zonale. Phytochemistry. 2013, 87, 96–101spa
dc.relation.referencesPereira, R. C.; Soares, A. R.; Teixeira, V. L.; Villaça, R.; Gama, B. A. P. da. Variation in Chemical Defenses against Herbivory in Southwestern Atlantic Stypopodium zonale (Phaeophyta). Bot. Mar. 2004, 47 (3).spa
dc.relation.referencesSoares, A. R.; Teixeira, V. L.; Pereira, R. C.; Villaça, R. Variation on Diterpene Production by the Brazilian Alga Stypopodium zonale (Dictyotales, Phaeophyta). Biochem. Syst. Ecol. 2003, 31 (11), 1347–1350.spa
dc.relation.referencesSusanto, E.; Fahmi, A. S.; Abe, M.; Hosokawa, M.; Miyashita, K. Lipids, Fatty Acids, and Fucoxanthin Content from Temperate and Tropical Brown Seaweeds. Aquat. Procedia. 2016, 7, 66–75.spa
dc.relation.referencesJaswir, I. Isolation of Fucoxanthin and Fatty Acids Analysis of Padina australis and Cytotoxic Effect of Fucoxanthin on Human Lung Cancer (H1299) Cell Lines. Afr. J. Biotechnol. 2011, 10 (81).spa
dc.relation.referencesHay, M.; Duffy, J.; Fenical, W.; Gustafson, K. Chemical Defense in the Seaweed Dictyopteris delicatula: Differential Effects against Reef Fishes and Amphipods. Mar. Ecol. Prog. Ser. 1988, 48, 185–192.spa
dc.relation.referencesMagalhaes, K. D.; Costa, L. S.; Fidelis, G. P.; Oliveira, R. M.; Nobre, L. T. D. B.; Dantas-Santos, N.; Camara, R. B. G.; Albuquerque, I. R. L.; Cordeiro, S. L.; Sabry, D. A.; Costa, M. S. S. P.; Alves, L. G.; Rocha, H. A. O. Anticoagulant, Antioxidant and Antitumor Activities of Heterofucans from the Seaweed Dictyopteris delicatula. Int. J. Mol. Sci. 2011, 12 (5), 3352–3365.spa
dc.relation.referencesTeixeira, V. L.; Kelecom, A. A Chemotaxonomic Study of Diterpenes from Marine Brown Algae of the Genus Dictyota. Sci. Total Environ. 1988, 75 (2–3), 271–283.spa
dc.relation.referencesDe Clerck, O.; Leliaert, F.; Verbruggen, H.; Lane, C. E.; De Paula, J. C.; Payo, D. A.; Coppejans, E. A Revised Classification Of The Dictyoteae (Dictyotales, Phaeophyceae) Based On Rbc L And 26s Ribosomal DNA Sequence Analyses. J. Phycol. 2006, 42 (6), 1271–1288.spa
dc.relation.referencesRushdi, M. I.; Abdel-Rahman, I. A. M.; Attia, E. Z.; Saber, H.; Saber, A. A.; Bringmann, G.; Abdelmohsen, U. R. The Biodiversity of the Genus Dictyota: Phytochemical and Pharmacological Natural Products Prospectives. Molecules. 2022, 27 (3), 672.spa
dc.relation.referencesHay, M. Marine Chemical Ecology: What’s Known and What’s next? Annu. Rev. Ecol. Syst. 1988, 19, 32.spa
dc.relation.referencesDuffy, E.; Hay, M. Seaweed Adaptations to Herbivory. BioScience. 1990, 40 (5), 368–375.spa
dc.relation.referencesRasher, D. B.; Stout, E. P.; Engel, S.; Kubanek, J.; Hay, M. E. Macroalgal Terpenes Function as Allelopathic Agents against Reef Corals. Proc. Natl. Acad. Sci. 2011, 108 (43), 17726–17731.spa
dc.relation.referencesSchmitt, T. M.; Lindquist, N.; Hay, M. E. Seaweed Secondary Metabolites as Antifoulants: Effects of Dictyota Spp. Diterpenes on Survivorship, Settlement, and Development of Marine Invertebrate Larvae. Chemoecology. 1998, 8 (3), 125–131.spa
dc.relation.referencesRubiano-Buitrago, P.; Duque, F.; Puyana, M.; Ramos, F. A.; Castellanos, L. Bacterial Biofilm Inhibitor Diterpenes from Dictyota Pinnatifida Collected from the Colombian Caribbean. Phytochem. Lett. 2019, 30, 74–80.spa
dc.relation.referencesPardo-Vargas, A.; de Barcelos Oliveira, I.; Stephens, P.; Cirne-Santos, C.; de Palmer Paixão, I.; Ramos, F.; Jiménez, C.; Rodríguez, J.; Resende, J.; Teixeira, V.; Castellanos, L. Dolabelladienols A–C, New Diterpenes Isolated from Brazilian Brown Alga Dictyota pfaffii. Mar. Drugs 2014, 12 (7), 4247–4259.spa
dc.relation.referencesCaamal-Fuentes, E.; Moo-Puc, R.; Freile-Pelegrín, Y.; Robledo, D. Cytotoxic and Antiproliferative Constituents from Dictyota ciliolata, Padina sanctae-crucis and Turbinaria tricostata. Pharm. Biol. 2014, 52 (10), 1244–1248.spa
dc.relation.referencesBeach, K.; Walters, L.; Borgeas, H.; Smith, C.; Coyer, J.; Vroom, P. The Impact of Dictyota Spp. on Halimeda Populations of Conch Reef, Florida Keys. J. Exp. Mar. Biol. Ecol. 2003, 297 (2), 141–159.spa
dc.relation.referencesPuyana, M. The Fate of Corals: Will They Overcome Competition with Algae and Cyanobacteria in a Changing Environment? In Corals in a Changing World; Beltran, C. D., Camacho, E. T., Eds.; InTech, 2018.spa
dc.relation.referencesLittler, D. S.; Littler, M. M. Caribbean Reef Plants, First edition.; OffShore Graphics: Washington DC, 2000.spa
dc.relation.referencesNunes Pinheiro, A. D.; Pereira Lopes-Filho, E. A.; De-Paula, J. C.; Pereira Netto, A. D.; Teixeira, V. L. Diterpenes from the Brown Alga Dictyota mertensii. Biochem. Syst. Ecol. 2019, 86, 103926.spa
dc.relation.referencesPaula, J. C.; Vallim, M. A.; Teixeira, V. L. What Are and Where Are the Bioactive Terpenoids Metabolites from Dictyotaceae (Phaeophyceae). Rev. Bras. Farmacogn. 2011, 21 (2), 216–228.spa
dc.relation.referencesAbou-El-Wafa, G.; Shaaban, M.; Shaaban, K.; El-Naggar, M.; Maier, A.; Fiebig, H.; Laatsch, H. Pachydictyols B and C: New Diterpenes from Dictyota dichotoma Hudson. Mar. Drugs. 2013, 11 (9), 3109–3123.spa
dc.relation.referencesCavalcanti, D. N.; de Oliveira, M.-A. R.; De-Paula, J. C.; Barbosa, L. S.; Fogel, T.; Pinto, M. A.; de Palmer Paixão, I. C. N.; Teixeira, V. L. Variability of a Diterpene with Potential Anti-HIV Activity Isolated from the Brazilian Brown Alga Dictyota menstrualis. J. Appl. Phycol. 2011, 23 (5), 873–876.spa
dc.relation.referencesPardo, A. Bioprospección de Productos Naturales Marinos de Organismos Bentónicos Del Litoral Brasileño y Caribe Colombiano- Fase I Tribu Dictyoteae. Título magister en ciencias, Universidad Nacional de Colombia, Bogota, 2013.spa
dc.relation.referencesHirschfeld, D. R.; Fenical, William.; Lin, G. H. Y.; Wing, R. M.; Radlick, Phillip.; Sims, J. J. Marine Natural Products. VIII. Pachydictyol A, an Exceptional Diterpene Alcohol from the Brown Alga, Pachydictyon coriaceum. J. Am. Chem. Soc. 1973, 95 (12), 4049–4050. https://doi.org/10.1021/ja00793a037.spa
dc.relation.referencesFattorusso, E.; Magno, S.; Mayol, L.; Santacroce, C.; Sica, D.; Amico, V.; Oriente, G.; Piattelli, M.; Tringali, C. Dictyol A and B, Two Novel Diterpene Alcohols from the Brown Alga Dictyota dichotoma. J. Chem. Soc. Chem. Commun. 1976, 14, 575.spa
dc.relation.referencesFaulkner, D. J.; Ravi, B. N.; Finer, J.; Clardy, J. Diterpenes from Dictyota dichotoma. Phytochemistry 1977, 16 (7), 991–993.spa
dc.relation.referencesDe Rosa, S.; De Stefano, S.; Zavodnik, N. Hydroazulenoid Diterpenes from the Brown Alga Dictyota dichotoma Var. Implexa. Phytochemistry. 1986, 25 (9), 2179–2181.spa
dc.relation.referencesWright, A. D.; König, G. M.; Sticher, O. New and Highly Oxidised Hydroazulenoid Diterpenes from the Tropical Marine Brown Alga Dictyota volubilis. Tetrahedron. 1993, 49 (3), 571–580.spa
dc.relation.referencesAyyad, S.-E. N.; Makki, M. S.; Al-kayal, N. S.; Basaif, S. A.; El-Foty, K. O.; Asiri, A. M.; Alarif, W. M.; Badria, F. A. Cytotoxic and Protective DNA Damage of Three New Diterpenoids from the Brown Alga Dictoyota dichotoma. Eur. J. Med. Chem. 2011, 46 (1), 175–182.spa
dc.relation.referencesDe Andrade Moura, L.; Marqui de Almeida, A. C.; Domingos, T. F.; Ortiz-Ramirez, F.; Cavalcanti, D. N.; Teixeira, V. L.; Fuly, A. L. Antiplatelet and Anticoagulant Effects of Diterpenes Isolated from the Marine Alga, Dictyota menstrualis. Mar. Drugs. 2014, 12 (5), 2471–2484.spa
dc.relation.referencesPereira, R.; Lourenço, A.; Terra, L.; Abreu, P.; Laneuville Teixeira, V.; Castro, H. Marine Diterpenes: Molecular Modeling of Thrombin Inhibitors with Potential Biotechnological Application as an Antithrombotic. Mar. Drugs. 2017, 15 (3), 79.spa
dc.relation.referencesSiless, G. E.; García, M.; Pérez, M.; Blustein, G.; Palermo, J. A. Large-Scale Purification of Pachydictyol A from the Brown Alga Dictyota dichotoma Obtained from Algal Wash and Evaluation of Its Antifouling Activity against the Freshwater Mollusk Limnoperna fortunei. J. Appl. Phycol. 2018, 30 (1), 629–636.spa
dc.relation.referencesDe-Paula, J.; Bueno, L.; Cavalcanti, D.; Yoneshigue-Valentin, Y.; Teixeira, V. Diterpenes from the Brown Alga Dictyota crenulata. Molecules. 2008, 13 (6), 1253–1262.spa
dc.relation.referencesCronin, G.; Hay, M. E. Within-Plant Variation in Seaweed Palatability and Chemical Defenses: Optimal Defense Theory versus the Growth-Differentiation Balance Hypothesis. Oecologia 1996, 105 (3), 361–368.spa
dc.relation.referencesFreitas, O. do S. P.; de Oliveira, A. S.; De-Paula, J. C.; Pereira, R. C.; Cavalcanti, D. N.; Teixeira, V. L. Chemical Variation in the Diterpenes from the Brazilian Brown Alga Dictyota mertensii (Dictyotaceae, Phaeophyta). Nat. Prod. Commun. 2007, 2 (1)spa
dc.relation.referencesHay, M.; Duffy, J. E.; Fenical, W. Host-Plant Specialization Decreases Predation on a Marine Amphipod: An Herbivore in Plant’s Clothing. Ecology. 1990, 71 (2), 733–743.spa
dc.relation.referencesCronin, G.; Hay, M. Susceptibility To Herbivores Depends On Recent History Of Both The Plant And Animau. 1996, 77, 13.spa
dc.relation.referencesDuffy, J. E.; Hay, M. E. Herbivore Resistance to Seaweed Chemical Defense: The Roles of Mobility and Predation Risk. Ecology. 1994, 75 (5), 1304–1319.spa
dc.relation.referencesPereira, R. C.; Cavalcanti, D. N.; Teixeira, V. L. Effects of Secondary Metabolites from the Tropical Brazilian Brown Alga Dictyota menstrualis on the Amphipod Parhyale hawaiensis. Mar. Ecol. Prog. Ser. 2000, 205, 95–100.spa
dc.relation.referencesAbraham, R. J.; Rowan, A. E. Nuclear Magnetic Resonance Spectroscopy of Chlorophyll. In Chlorophylls; CRC Press, 1991; pp 797–834.spa
dc.relation.referencesWright, S. W.; Jeffrey, S. W. Fucoxanthin Pigment Markers of Marine Phytoplankton Analysed by HPLC and HPTLC. Mar. Ecol. Prog. Ser. 1987, 38 (3), 259–266spa
dc.relation.referencesMori, K.; Ooi, T.; Hiraoka, M.; Oka, N.; Hamada, H.; Tamura, M.; Kusumi, T. Fucoxanthin and Its Metabolites in Edible Brown Algae Cultivated in Deep Seawater. Mar. Drugs. 2004, 2 (2), 63–72.spa
dc.relation.referencesKumar, H.; Singh, H. A Textbook on Algae; Affiliated East-West Press, 1976.spa
dc.relation.referencesLee, R. E. Phycology, Fourth Edition, 4th ed.; Cambridge University Press: New York, 2008.spa
dc.relation.referencesGraham, J.; Wilcox, L.; Graham, L. Algae, segunda.; Benjamin Cummings: San Francisco, Estados Unidos, 2008.spa
dc.relation.referencesThe Algae World; Sahoo, D., Seckbach, J., Eds.; Cellular origin, life in extreme habitats and astrobiology; Springer: Dordrecht Heidelberg New York London, 2015.spa
dc.relation.referencesMuradian, Kh.; Vaiserman, A.; Min, K.-J.; Fraifeld, V. E. Fucoxanthin and Lipid Metabolism: A Minireview. Nutr. Metab. Cardiovasc. Dis. 2015, 25 (10), 891–897.spa
dc.relation.referencesGammone, M. A.; D’Orazio, N. Anti-Obesity Activity of the Marine Carotenoid Fucoxanthin. Mar. Drugs. 2015, 13 (4), 2196–2214.spa
dc.relation.referencesPaul, V. J.; Puglisi, M. P.; Ritson-Williams, R. Marine Chemical Ecology. Nat. Prod. Rep. 2006, 23 (2), 153.spa
dc.relation.referencesChen, J.; Li, H.; Zhao, Z.; Xia, X.; Li, B.; Zhang, J.; Yan, X. Diterpenes from the Marine Algae of the Genus Dictyota. Mar. Drugs. 2018, 16 (5), 159.spa
dc.relation.referencesCheng, S.; Zhao, M.; Sun, Z.; Yuan, W.; Zhang, S.; Xiang, Z.; Cai, Y.; Dong, J.; Huang, K.; Yan, P. Diterpenes from a Chinese Collection of the Brown Alga Dictyota plectens. J. Nat. Prod. 2014, 77 (12), 2685–2693.spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacionalspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.subject.ddc540 - Química y ciencias afinesspa
dc.subject.lembAlgas marinasspa
dc.subject.lembMarine algaeeng
dc.subject.lembOrganismos marinosspa
dc.subject.lembMarine organismseng
dc.subject.proposalCanistrocarpusspa
dc.subject.proposalDiterpenosspa
dc.subject.proposalPachydictyol Aspa
dc.subject.proposalIsopachydictiol Aspa
dc.subject.proposalAcetato de dictyol Bspa
dc.subject.proposalPerfilado metabólicospa
dc.subject.proposalAlgas pardasspa
dc.subject.proposalSan Andrés islaspa
dc.subject.proposalCaribe colombianospa
dc.titleAlgas pardas de la Isla de San Andrés, Caribe Colombiano: Caracterización metabolómicaspa
dc.title.translatedBrown algae from San Andrés Island, Colombian Caribbean: Metabolomic characterizationeng
dc.typeTrabajo de grado - Maestríaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/masterThesisspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TMspa
dc.type.versioninfo:eu-repo/semantics/acceptedVersionspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa

Archivos

Bloque original

Mostrando 1 - 1 de 1
Miniatura
Nombre:
1123627401.2023.pdf
Tamaño:
8.18 MB
Formato:
Adobe Portable Document Format
Descripción:
Tesis de Maestría en Ciencias - Química
Descargar

Bloque de licencias

Mostrando 1 - 1 de 1
Miniatura
Nombre:
license.txt
Tamaño:
5.74 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Maestría en Ciencias - Química