Revisión bibliográfica de conceptos morfológicos en el desarrollo de Enfermedad de Hígado Graso no Alcohólico (EHGNA) y Esteatohepatitis no Alcohólica (EHNA)

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dc.contributor.advisorArias López, Luz Amparospa
dc.contributor.authorGonzález Arias, Julián Enriquespa
dc.date.accessioned2024-12-11T15:07:57Z
dc.date.available2024-12-11T15:07:57Z
dc.date.issued2024
dc.descriptionilustraciones, diagramasspa
dc.description.abstractLa Enfermedad de Hígado Graso no Alcohólico (EHGNA), es un tipo de hepatopatía crónica que actualmente está en crecimiento e impacta la vida de pacientes con comorbilidades metabólicas como la obesidad y la Diabetes Mellitus tipo II, que con el tiempo pueden desarrollar Esteatohepatitis no Alcohólica (EHNA), en el contexto de inflamación crónica que los pone en riesgo de desarrollar cirrosis y finalmente Hepatocarcinoma. Este tipo de patologías afecta a nivel funcional al hígado, afecciones explicables por alteraciones a múltiples niveles -molecular, celular, tisular y macroscópico-. El objetivo del presente trabajo de grado es realizar una revisión bibliográfica sobre conceptos morfológicos -en cuanto a la embriología, anatomía e histología- del hígado normal y de cómo la comprensión de estos conceptos nos permite entender los cambios patológicos y fisiopatológicos que sufre el hígado en estas patologías. Se encontraron múltiples interacciones complejas en los múltiples niveles mencionados que explican lo que sucede en la enfermedad, permitiendo identificar posibles perspectivas futuras para impactar de forma positiva a los pacientes (Texto tomado de la fuente).spa
dc.description.abstractNon-Alcoholic Fatty Liver Disease (NAFLD) is a type of chronic liver disease that is currently growing and impacts the lives of patients with metabolic comorbidities such as obesity and Type II Diabetes Mellitus, who over time can develop Non-Alcoholic Steatohepatitis. (NASH), in the context of chronic inflammation that puts them at risk of developing cirrhosis and finally Hepatocarcinoma. This type of pathology affects the liver at a functional level, conditions that can be explained by alterations at multiple levels - molecular, cellular, tissue and macroscopic-. The objective of this tesis is to carry out a bibliographic review on morphological concepts - in terms of embryology, anatomy and histology - of the normal liver and how the understanding of these concepts allows us to understand the pathological and pathophysiological changes that the liver undergoes in these pathologies. Multiple complex interactions were found at the multiple levels mentioned, that explain what happens in the disease, allowing the identification of possible future perspectives to positively impact patients.eng
dc.description.degreelevelMaestríaspa
dc.description.degreenameMagíster en Morfología Humanaspa
dc.description.researchareaTrabajo de Grado de Profundizaciónspa
dc.format.extent153 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameUniversidad Nacional de Colombiaspa
dc.identifier.reponameRepositorio Institucional Universidad Nacional de Colombiaspa
dc.identifier.repourlhttps://repositorio.unal.edu.co/spa
dc.identifier.urihttps://repositorio.unal.edu.co/handle/unal/87290
dc.language.isospaspa
dc.publisherUniversidad Nacional de Colombiaspa
dc.publisher.branchUniversidad Nacional de Colombia - Sede Bogotáspa
dc.publisher.facultyFacultad de Medicinaspa
dc.publisher.placeBogotá, Colombiaspa
dc.publisher.programBogotá - Medicina - Maestría en Morfología Humanaspa
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.licenseAtribución-NoComercial 4.0 Internacionalspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/spa
dc.subject.ddc610 - Medicina y salud::616 - Enfermedadesspa
dc.subject.decsEnfermedad del Hígado Graso no Alcohólicospa
dc.subject.decsNon-alcoholic Fatty Liver Diseaseeng
dc.subject.decsCarcinoma Hepatocelularspa
dc.subject.decsCarcinoma, Hepatocellulareng
dc.subject.decsEnfermedades del Sistema Digestivospa
dc.subject.decsDigestive System Diseaseseng
dc.subject.proposalEnfermedad por Hígado Graso No Alcohólicospa
dc.subject.proposalEsteatohepatitis no Alcohólicaspa
dc.subject.proposalAnatomíaspa
dc.subject.proposalEmbriologíaspa
dc.subject.proposalHistologíaspa
dc.subject.proposalNon-alcoholic Fatty Liver Diseaseeng
dc.subject.proposalNon-alcoholic Steatohepatitiseng
dc.subject.proposalAnatomyeng
dc.subject.proposalEmbryologyeng
dc.subject.proposalHistologyeng
dc.titleRevisión bibliográfica de conceptos morfológicos en el desarrollo de Enfermedad de Hígado Graso no Alcohólico (EHGNA) y Esteatohepatitis no Alcohólica (EHNA)spa
dc.title.translatedBibliographic review of morphological concepts in the development of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)eng
dc.typeTrabajo de grado - Maestríaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
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dcterms.audience.professionaldevelopmentInvestigadoresspa
dcterms.audience.professionaldevelopmentMaestrosspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa

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