Hidroxiprolina en enfermedades reumáticas
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Chalem B., Fernando
Peña C., Mario
Lizarazo P., Humberto
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EspañolFecha de publicación
1972
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Se presenta un estudio de 64 casos, 16 normales, 10 de artritis reumatoidea, 5 de lupus eritematoso sitémico, 30 de osteoporosis, 2 de raquitismo vitamino D resistente y 1 de osteomalacia, basado en el comportamiento de la hidroxiprolina, aminoácido derivado de la prolina que es considerado en la actualidad como de gran valor en el estudio del metabolismo del colágeno. Se analizan los resultados obtenidos en cada uno de los grupos de enfermedades y se comparan con los datos obtenidos en el grupo de individuos normales. Creemos que estos últimos son de gran utilidad para fijar los promedios normales de hidroxiprolina libre en el suelo y de hidroxiprolina total y libre en la orina, en nuestro medio ya que no hemos encontrado datos al respecto en la bibliografía nacional consultada.
A study based on the behaviour of hydroxyproline in 64 cases, 16 normal individuals, 10 with rheumatoid arthritis, 5 with systemic lupus erythematosus, 30 with osteoporois, 2 with vitamin D resistant rickets and 1 with osteomalacia, is presented, hydroxyproline is an amino acid derived from proline and is actually considered of great value in the study of collagen metabolism. The results obtained in each group of disease are presented and compared with those obtained in the normal individuals. We think that these late are very useful to establish in our medium, the average of normal free serum hydroxyproline and of total and free urine hydroxyproline, since we did not find related data in the consulted ational literature.
A study based on the behaviour of hydroxyproline in 64 cases, 16 normal individuals, 10 with rheumatoid arthritis, 5 with systemic lupus erythematosus, 30 with osteoporois, 2 with vitamin D resistant rickets and 1 with osteomalacia, is presented, hydroxyproline is an amino acid derived from proline and is actually considered of great value in the study of collagen metabolism. The results obtained in each group of disease are presented and compared with those obtained in the normal individuals. We think that these late are very useful to establish in our medium, the average of normal free serum hydroxyproline and of total and free urine hydroxyproline, since we did not find related data in the consulted ational literature.