Búsqueda de posibles compuestos con actividad insecticida a partir de cianobacterias del Caribe colombiano
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Resumen: Se estudiaron tres mats de cianobacterias usando fraccionamiento bioguiado con el ensayo larvicida contra Aedes aegypti. Como compuestos activos se aislaron ácidos grasos insaturados, dos nuevos análogos de dolastatina D y el ácido seco malyngólido (nuevo), también la neodysidenina que afectó el desarrollo larvario y un heptapéptido cíclico nuevo mostró actividad promisoria.
Abstract: Three cyanobacterial mats were chemical studied using a bioguide approach with larvicide assay against Aedes aegypti. Active isolated compounds correspond to unsaturated fatty acids, two novel dolastatine D analogs and malyngolide seco acid (new). Neodysidenin exhibited larvae growth disruption and novel cyclic heptapeptide showed a promising activity.
Abstract: Three cyanobacterial mats were chemical studied using a bioguide approach with larvicide assay against Aedes aegypti. Active isolated compounds correspond to unsaturated fatty acids, two novel dolastatine D analogs and malyngolide seco acid (new). Neodysidenin exhibited larvae growth disruption and novel cyclic heptapeptide showed a promising activity.